Structure of the UNC5H2 death domain

Acta Crystallographica Section D: Biological Crystallography

Volumn 62, Issue 12, 2006, Pages 1502-1509

  Handa, Noriko ^a   Kukimoto Niino, Mutsuko ^a   Akasaka, Ryogo ^a   Murayama, Kazutaka ^a,b   Terada, Takaho ^a   Inoue, Makoto ^a   Yabuki, Takashi ^a   Aoki, Masaaki ^a   Seki, Eiko ^a   Matsuda, Takayoshi ^a   Nunokawa, Emi ^a   Tanaka, Akiko ^a   Hayashizaki, Yoshihide ^a   Kigawa, Takanori ^a,c   Shirouzu, Mikako ^a   Yokoyama, Shigeyuki ^a,d  

^a RIKEN YOKOHAMA INSTITUTE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

Apoptosis; Death domain; Homodimer; Netrin 1 receptors; Tumour suppressors; UNC5H2

Indexed keywords

CELL SURFACE RECEPTOR; NERVE GROWTH FACTOR; NETRIN 1; NETRIN RECEPTORS; NETRIN-1; TUMOR SUPPRESSOR PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CHEMISTRY; DIMERIZATION; MOLECULAR GENETICS; MOUSE; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; ANIMALS; DIMERIZATION; MICE; MOLECULAR SEQUENCE DATA; NERVE GROWTH FACTORS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; SEQUENCE ALIGNMENT; TUMOR SUPPRESSOR PROTEINS;

EID: 33845486751     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444906039369     Document Type: Article

References (59)

1. Arakawa, H. (2004). Nature Rev. Cancer, 4, 978-987.
2. Arakawa, H. (2005). Cell Death Differ. 12, 1057-1065.
3. Bang, S., Jeong, E. J., Kim, I. K., Jung, Y. K. & Kim, K. S. (2000). J. Biol. Chem. 275, 36217-36222.
4. Berglund, H., Olerenshaw, D., Sankar, A., Federwisch, M., McDonald, N. Q. & Driscoll, P. C. (2000). J. Mol. Biol. 302, 171-188.
5. Bredesen, D. E., Mehlen, P. & Rabizadeh, S. (2004). Physiol. Rev. 84, 411-430.
6. Brünger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J.-S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T. & Warren, G. L. (1998). Acta Cryst. D54, 905-921.
7. Carninci, P. et al. (2003). Genome Res. 13, 1273-1289.
8. Carrington, P. E., Sandu, C., Wei, Y., Hill, J. M., Morisawa, G., Huang, T., Gavathiotis, E., Wei, Y. & Werner, M. H. (2006). Mol. Cell, 22, 599-610.
9. Choi, C. & Benveniste, E. N. (2004). Brain Res. Brain Res. Rev. 44, 65-81.
10. Feinstein, E., Kimchi, A., Wallach, D., Boldin, M. & Varfolomeev, E. (1995). Trends Biochem. Sci. 20, 342-344.
11. Hill, J. M., Morisawa, G., Kim, T., Huang, T., Wei, Y., Wei, Y. & Werner, M. H. (2004). J. Biol. Chem. 279, 1474-1481.
12. Hofmann, K. & Tschopp, J. (1995). FEBS Lett. 371, 321-323.
13. Holm, L. & Sander, C. (1997). Nucleic Acids Res. 25, 231-234.
14. Hong, K., Hinck, L., Nishiyama, M., Poo, M. M., Tessier-Lavigne, M. & Stein, E. (1999). Cell, 97, 927-941.
15. Hsu, H., Xiong, J. & Goeddel, D. V. (1995). Cell, 81, 495-504.
16. Huang, B., Eberstadt, M., Olejniczak, E. T., Meadows, R. P. & Fesik, S. W. (1996). Nature (London), 384, 638-641.
17. Jeong, E. J., Bang, S., Lee, T. H., Park, Y. I., Sim, W. S. & Kim, K. S. (1999). J. Biol. Chem. 274, 16337-16342.
18. Keino-Masu, K., Masu, M., Hinck, L., Leonardo, E. D., Chan, S. S., Culotti, J. G. & Tessier-Lavigne, M. (1996). Cell, 87, 175-185.
19. Keleman, K. & Dickson, B. J. (2001). Neuron, 32, 605-617.
20. Kigawa, T., Yabuki, T., Matsuda, N., Matsuda, T., Nakajima, R., Tanaka, A. & Yokoyama, S. (2004). J. Struct. Funct. Genomics, 5, 63-68.
21. Kigawa, T., Yabuki, T. & Yokoyama, S. (1999). Tanpakushitsu Kakusan Koso, 44, 598-605.
22. Kigawa, T., Yabuki, T., Yoshida, Y., Tsutsui, M., Ito, Y., Shibata, T. & Yokoyama, S. (1999). FEBS Lett. 442, 15-19.
23. Kohl, A. & Grutter, M. G. (2004). C. R. Biol. 327, 1077-1086.
24. Koradi, R., Billeter, M. & Wuthrich, K. (1996). J. Mol. Graph. 14, 51-55.
25. Kraulis, P. J. (1991). J. Appl. Cryst. 24, 946-950.
26. Lasker, M. V., Gajjar, M. M. & Nair, S. K. (2005). J. Immunol. 175, 4175-4179.
27. Laskowski, R. A., Rullmannn, J. A., MacArthur, M. W., Kaptein, R. & Thornton, J. M. (1996). J. Biomol. NMR, 8, 477-486.
28. Laue, T. M., Shah, B., Ridgeway, T. M. & Pelletier, S. L. (1992). Analytical Ultracentrifugation in Biochemistry and Polymer Science, edited by S. E. Harding, A. D. Rowe & J. C. Horton, pp. 90-125. Cambridge: Royal Society of Chemistry.
29. Leonardo, E. D., Hinck, L., Masu, M., Keino-Masu, K., Ackerman, S. L. & Tessier-Lavigne, M. (1997). Nature (London), 386, 833-838.
30. Liepinsh, E., Ilag, L. L., Otting, G. & Ibanez, C. F. (1997). EMBO J. 16, 4999-5005.
31. Llambi, F., Causeret, F., Bloch-Gallego, E. & Mehlen, P. (2001). EMBO J. 20, 2715-2722.
32. Llambi, F., Laurenco, F. C., Gozuacik, D., Guix, C., Pays, L., Del Rio, G., Kimchi, A. & Mehlen, P. (2005). EMBO J. 24, 1192-1201.
33. Martin, D. A., Zheng, L., Siegel, R. M., Huang, B., Fisher, G. H., Wang, J., Jackson, C. E., Puck, J. M., Dale, J., Straus, S. E., Peter, M. E., Krammer, P. H., Fesik, S. & Lenardo, M. J. (1999). Proc. Natl Acad. Sci. USA, 96, 4552-4557.
34. Mazelin, L., Bernet, A., Bonod-Bidaud, C., Pays, L., Arnaud, S., Gespach, C., Bredesen, D. E., Scoazec, J. Y. & Mehlen, P. (2004). Nature (London), 431, 80-84.
35. Mehlen, P. & Furne, C. (2005). Cell. Mol. Life Sci. 62, 2599-2616.
36. Mehlen, P. & Mazelin, L. (2003). Biol. Cell, 95, 425-436.
37. Mehlen, P., Rabizadeh, S., Snipas, S. J., Assa-Munt, N., Salvesen, G. S. & Bredesen, D. E. (1998). Nature (London), 395, 801-804.
38. Merritt, E. A. & Murphy, M. E. (1994). Acta Cryst. D50, 869-873.
39. Otwinowski, Z. & Minor, W. (1997). Methods Enzymol. 276, 307-326.
40. Park, H. H. & Wu, H. (2006). J. Mol. Biol. 357, 358-364.
41. Plaizier-Vercammen, J. A. & De Neve, R. E. (1982). J. Pharm. Sci. 71, 552-556.
42. Qin, H., Srinivasula, S. M., Wu, G., Fernandes-Alnemri, T., Alnemri, E. S. & Shi, Y. (1999). Nature (London), 399, 549-557.
43. Schuck, P. (1998). Biophys. J. 75, 1503-1512.
44. Siegel, R. M., Frederiksen, J. K., Zacharias, D. A., Chan, F. K., Johnson, M., Lynch, D., Tsien, R. Y. & Lenardo, M. J. (2000). Science, 288, 2354-2357.
45. Smith, C. A., Farrah, T. & Goodwin, R. G. (1994). Cell, 76, 959-962.
46. Stein, E., Zou, Y., Poo, M. & Tessier-Lavigne, M. (2001). Science, 291, 1976-1982.
47. Straus, S. E. et al. (2001). Blood, 98, 194-200.
48. Sukits, S. F., Lin, L. L., Hsu, S., Malakian, K., Powers, R. & Xu, G. Y. (2001). J. Mol. Biol. 310, 895-906.
49. Tanikawa, C., Matsuda, K., Fukuda, S., Nakamura, Y. & Arakawa, H. (2003). Nature Cell Biol. 5, 216-223.
50. Telliez, J. B., Xu, G. Y., Woronicz, J. D., Hsu, S., Wu, J. L., Lin, L., Sukits, S. F., Powers, R. & Lin, L. L. (2000). J. Mol. Biol. 300, 1323-1333.
51. Terwilliger, T. (2004). J. Synchrotron Rad. 11, 49-52.
52. Terwilliger, T. C. & Berendzen, J. (1999). Acta Cryst. D55, 849-861.
53. Thiebault, K., Mazelin, L., Pays, L., Llambi, F., Joly, M. O., Scoazec, J. Y., Saurin, J. C., Romeo, G. & Mehlen, P. (2003). Proc. Natl Acad. Sci. USA, 100, 4173-4178.
54. Vaishnaw, A. K., Orlinick, J. R., Chu, J. L., Krammer, P. H., Chao, M. V. & Elkon, K. B. (1999). J. Clin. Invest. 103, 355-363.
55. Vaughn, D. E., Rodriguez, J., Lazebnik, Y. & Joshua-Tor, L. (1999). J. Mol. Biol. 293, 439-447.
56. Wada, T., Shirouzu, M., Terada, T., Ishizuka, Y., Matsuda, T., Kigawa, T., Kuramitsu, S., Park, S. Y., Tame, J. R. & Yokoyama, S. (2003). Acta Cryst. D59, 1213-1218.
57. Wang, J. J., Rabizadeh, S., Tasinato, A., Sperandio, S., Ye, X., Green, M., Assa-Munt, N., Spencer, D. & Bredesen, D. E. (2000). J. Neurosci. Res. 60, 587-593.
58. Weber, C. H. & Vincenz, C. (2001). Trends Biochem. Sci. 26, 475-481.
59. Xiao, T., Towb, P., Wasserman, S. A. & Sprang, S. R. (1999). Cell, 99, 545-555.