Gene expression in gastric biopsies from patients infected with Helicobacter pylori

Scandinavian Journal of Gastroenterology

Volumn 39, Issue 12, 2004, Pages 1192-1200

  Mannick, Elizabeth E ^a   Schurr, J R ^a   Zapata, A ^a   Lentz, J J ^a   Gastanaduy, M ^a   Cote, R L ^a   Delgado, A ^a   Correa, P ^a   Correa, H ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Gastric intrinsic factor; Gene expression; Helicobacter; Metallothionein; Microarray

Indexed keywords

IMMUNOGLOBULIN; INTRINSIC FACTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; METALLOTHIONEIN;

ADULT; AGED; APOPTOSIS; ARTICLE; B LYMPHOCYTE ACTIVATION; BACTERIAL INFECTION; BACTERIAL STRAIN; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA MICROARRAY; FEMALE; GASTROSCOPY; GENE EXPRESSION; HELICOBACTER PYLORI; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNITY; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; STOMACH BIOPSY;

ADULT; AGED; APOPTOSIS; CASE-CONTROL STUDIES; FEMALE; GASTRIC MUCOSA; GASTRITIS; GENE EXPRESSION PROFILING; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNITY; INFLAMMATION; MIDDLE AGED; NEOPLASM PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PYLORIC ANTRUM; WOUND HEALING;

EID: 10644231602     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.1080/00365520410003588     Document Type: Article

References (72)

1. Correa P, Haenszel W, Cuello C, Tannenebaum S, Archer M. A model for gastric cancer epidermiology. Lancet 1975;2:58-60.
2. Blaser MJ, Perez-Perez GI, Keanthous H, Cover TL, Peek RM, Chyou PH, et al. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res 1995; 55:2111-5.
3. Gerhard M, Lehn N, Neumayer N, Boren T, Rad R, Schepp W, et al. Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesion. Proc Natl Acad Sci USA 1999; 96:12778-83.
4. El-Omar EM, Carrington M, Chow WH, McColl KE, Bream JH, Young HA, et al. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 2000;404:398-402.
5. Katoh T, Boissy R, Nagata N, Kitagawa K, Kuroda Y, Itoh H, et al. Inherited polymorphism in the N-acetyltransferase 1 (NAT1) and 2 (NAT2) genes and susceptibility to gastric and colorectal adenocarcinoma. Int J Cancer 2000;85:46-9.
6. Farinati F, Cardin R, Degan P, Rugge M, Mario FD, Bonvicini P, et al. Oxidative DNA damage accumulation in gastric carcinogenesis. Gut 1998;42:351-6.
7. Maeda S, Otsuka M, Hirata Y, Mitsuno Y, Yoshida H, Shiratori Y, et al. cDNA microarray analysis of Helicobacter pylori-mediated alteration of gene expression in gastric cancer cells. Biochem Biophys Res Commun 2001;284:443-9.
8. Sepulveda AR, Tao H, Carloni E, Sepulveda J, Graham DY, Peterson LE. Screening of gene expression profiles in gastric epithelial cells induced by Helicobacter pylori using microarray analysis. Aliment Pharmacol Ther 2002;Suppl 2:145-57.
9. Nagasako T, Sugiyama T, Mizushima T, Miura Y, Kato M, Asaka M. Upregulated Smad5 mediates apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. J Biol Chem 2003;278:4821-5.
10. Yoshida N, Ishikawa T, Ichiishi E, Yoshida Y, Hanashiro K, Kuchide M, et al. The effect of rebamipide on Helicobacter pylori extract-mediated changes of gene expression in gastric epithelial cells. Aliment Pharmacol Ther 2003;18:63-75.
11. Terres AM, Pajares JM, O'Toole D, Ahern S, Kelleher D. H. pylori infection is associated with downregulation of E-cadherin, a molecule involved in epithelial cell adhesion and proliferation control. J Clin Pathol 1998;51:410-2.
12. Sambrook J, Fritsch EF, Maniatis T, editors. Molecular cloning: a laboratory manual. 2nd ed. Plainview, NY: Cold Spring Harbor Laboratory Press; 1989. p. E.3-E.4.
13. Golay JT, Clark EA, Beverley PC. The CD20 (Bp35) antigen is involved in activation of B cells from the G0 to the G1 phase of the cell cycle. J Immunol 1985;135:3795-801.
14. Okada T, Ngo VN, Ekland EH, Forster R, Lipp M, Littman DR, et al. Chemokine requirements for B cell entry to lymph nodes and Peyer's patches. J Exp Med 2002;196:65-75.
15. Reid KB, Colomb M, Petry F, Loos M. Complement component C1 and the collectins: first-line defense molecules in innate and acquired immunity. Trends Immunol 2002;23:115-7.
16. Mancek M, Pristovsek P, Jerala R. Identification of LPS-binding peptide fragment of MD-2, a toll-receptor accessory protein. Biochem Biophys Res Commun 2002;292:880-5.
17. Cantrell MA, Anderson D, Cerretti DP, Price V, McKereghan K, Tushinski RJ, et al. Cloning, sequence, and expression of a human granulocyte/macrophage colony-stimulating factor. Proc Natl Acad Sci USA 1985;82:6250-4.
18. Adema GJ, Hargers F, Verstraten R, de Vries E, Marland G, Menon S, et al. A dendritic-cell-derived C-C chemokine that preferentially attracts naïve T cells. Nature. 1997;387:713-7.
19. Bates EE, Ravel O, Dieu MC, Ho S, Guret C, Bridon JM, et al. Identification and analysis of a novel member of the Ubiquitin family expressed in dendritic cells and mature B cells. Eur J Immunol 1997;27:2471-7.
20. Hamanaka Y, Nakashima M, Wada A, Ito M, Kurazono H, Hojo H, et al. Expression of human beta-defensin 2 (hBD-2) in Helicobacter pylori induced gastritis: antibacterial effect of hBD-2 against Helicobacter pylori. Gut 2001;49:481-7.
21. Shinozaki S, Nakamura T, Iimura M, Kato Y, Iizuka B, Kobayashi M, et al. Upregulation of Reg 1alpha and GW112 in the epithelium of inflamed colonic mucosa. Gut 2001;48:623-9.
22. Dusetti NJ, Ortiz EM, Mallo GV, Dagorn JC, Iovanna JL. Pancreatitis-associated protein 1 (PAP I), an acute phase protein induced by cytokines. Identification of two functional interleukin-6 response elements in the rat PAP I promoter region. J Biol Chem 1995;270:22417-21.
23. Alberati-Giani D, Ricciardi-Castagnoli P, Kohler C, Cesura AM. Regulation of the kynurenine metabolic pathway by interferon-gamma in murine cloned macrophages and microglial cells. J Neurochem 1996;66:996-1004.
24. Marie M, Arunachalam B, Phan UT, Dong C, Garrett WS, Cannon KS, et al. Defective antigen processing in G1LT-free mice. Science 2001;294:1361-5.
25. Campbell DR, Haber MM, Sheldon E, Collis C, Lukasik N, Huang B, et al. Effect of H. pylori status on gastric ulcer healing in patients continuing nonsteroidal anti-inflammatory therapy and receiving treatment with lansoprazole or ranitidine. Am J Gastroenterol 2002;97:2208-14.
26. Gooz M, Gooz P, Smolka AJ. Epithelial and bacterial metallo-proteinases and their inhibitors in H. pylori infection of human gastric cells. Am J Physiol Gastrointest Liver Physiol 2001;281: G823-32.
27. Ashcroft GS, Lei K, Jin W, Longenecker G, Kulkarni AB, Greenwell-Wild T, et al. Secretory leukocyte protease inhibitor mediates non-redundant functions necessary for normal wound healing. Nat Med 2000;6:1147-53.
28. Galliano MF, Huet C, Frygelius J, Polgren A, Wewer UM, Engvall E. Binding of ADAM 12, a marker of skeletal muscle regeneration, to the muscle-specific actin-binding protein, alpha-actinin-2, is required for myoblast fusion. J Biol Chem 2000; 275:13933-9.
29. Maeda S, Yoshida H, Mitsuno Y, Hirata Y, Ogura K, Shiratori Y, et al. Analysis of apoptotic and antiapoptotic signaling pathways induced by Helicobacter pylori. Mol Pathol 2002;55:296-3.
30. Wang J, Brooks EG, Bamford KB, Denning TL, Pappo J, Ernst PB. Negative selection of T cells by Helicobacter pylori as a model for bacterial strain selection by immune evasion. J Immunol 2001;167:926-34.
31. Devireddy LR, Teodoro JG, Richard FA, Green MR. Induction of apoptosis by a secreted lipocalin that is transcriptionally regulated by 1L-3 deprivation. Science 2001;293:829-34.
32. Fallarino F, Grohmann U, Vacca C, Bianchi R, Orabona C, Spreca A, et al. T cell apoptosis by tryptophan catabolism. Cell Death Differ 2002;9:1069-77.
33. Sharief MK, Noori MA, Zoukos Y. Reduced expression of the inhibitor of apoptosis proteins in T cells from patients with multiple sclerosis following interferon-beta therapy. J Neuroimmunol 2002;129:224-31.
34. Wang X, Hirmo S, Willen R, Wadstrom T. Inhibition of Helicobacter pylori infection by bovine milk glycoconjugates in a BA1b/cA mouse model. J Med Microbiol 2001;50:430-5.
35. Schade SG, Feick P, Muckerheide M, Schilling RF. Occurrence in gastric juice of antibody to a complex of intrinsic factor and vitamin B12. N Engl J Med. 1966;275:528-31.
36. Becker RM, Darrow C, Zimonjic DB, Popescu NC, Watson MA, Fleming TP. Identification of mammaglobin B, a novel member of the uteroglobin family. Genomics. 1998;54:70-8.
37. Bosserhoff AK, Kaufmann M, Kaluza B, Bartke I, Zirngibl H, Hein R, et al. Melanoma-inhibiting activity, a novel serum marker for progression of malignant melanoma. Cancer Res 1997;57:3149-53.
38. Tsujikawa K, Kawakami N, Uchino Y, Ichijo T, Furukawa T, Saito H, et al. Distinct functions of the two protein tyrosine phosphatase domains of LAR (leukocyte common antigen-related) on tyrosine dephosphorylation of insulin receptor. Mol Cell Endocrinol 2001;15:271-80.
39. Weiskirchen R, Pino JD, Macalma T, Bister K, Beckerle MC. The cysteine-rich protein family of highly related L1M domain proteins. J Biol Chem 1995;270:28946-54.
40. Tanizawa Y, Riggs AC, Dagogo-Jack S, Vaxillaire M, Froguel P, Liu L, et al. Isolation of the human L1M/homeodomain gene islet-1 and identification of a simple sequence repeat 1. Diabetes 1994;43:935-41.
41. Scheynius A, Engstrand L. Gastric epithelial cells in Helicobacter pylori-associated gastritis express HLA-DR but not 1CAM-1. Scand J Immunol 1991;33:237-41.
42. Mattsson A, Quiding-Jarbrink M, Lonroth H, Hamlet A, Ahlstedt I, Svennerholm A. Antibody-secreting cells in the stomachs of symptomatic and asymptomatic Helicobacter pylori-infected subjects. Infect Immun 1998;66:2705-12.
43. Wotherspoon AC, Ortiz-Hidalgo C, Falzon MR. Isaacson PG. Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma. Lancet 1991;338:1175-6.
44. Kawahara T, Teshima S, Oka A, Sugiyama T, Kishi K, Rokutan K. Type I Helicobacter pylori lipopolysaccharide stimulates toll-like receptor 4 and activates mitogen oxidase 1 in gastric pit cells. Infect Immun 2001;69:4382-9.
45. Ernst P. Review article: the role of inflammation in the pathogenesis of gastric cancer. Aliment Pharmacol Ther 1999:13 Suppl 1:13-8.
46. Bamford KB, Fan X, Crowe SE, Leary JF, Gourley WK. Luthra GK, et al. Lymphocytes in the human gastric mucosa during Helicobacter pylori have a T helper cell 1 phenotype. Gastroenterology. 1998;114:482-92.
47. Farkus H, Fust G, Fekete B, Karadi I, Varga L. Eradication of Helicobacter pylori and improvement of hereditary angioneurotic oedema. Lancet 2001;358:1695-6.
48. Forman D, Webb P, Parsonnet J. H pylori and gastric cancer. Lancet 1994;343:243-4.
49. Obst B, Schutz S, Ledig S, Wagner S, Beil W. Helicobacter pylori-induced apoptosis in gastric epithelial cells is blocked by protein kinase C activation. Microb Pathog 2002;33:167-75.
50. Xia HH, Talley NJ. Apoptosis in gastric epithelium induced by Helicobacter pylori infection: implications in gastric carcinogenesis. Am J Gastroenterol 2001;96:16-26.
51. Goetz DH, Holmes MA, Borregaard N, Bluhm ME, Raymond KN, Strong RK. The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition. Mol Cell 2002;10:1033-43.
52. Fan X, Crowe SE, Behar S, Gunasena H, Ye G, Haeberle H, et al. The effect of class II major histocompatibility complex expression on adherence of Helicobacter pylori and induction of apoptosis in gastric epithelial cells: a mechanism for T helper cell type 1-mediated damage. J Exp Med 1998;187:1659-69.
53. Shapiro SD, Kobayashi DK, Ley TJ. Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages. J Biol Chem 1993;268:23824-9.
54. Weinrauch Y, Drujan D, Shapiro SD, Weiss J, Zychlinsky A. Neutrophil elastase targets virulence factors of enterobacteria. Nature 2002;417:91-4.
55. Takemura T, Granger DN, Evans EJ, Jr, Evans DG, Graham DY, Anderson DC, et al. Extract of Helicobacter pylori induces neutrophils to injure endothelial cells and contains antielastase activity. Gastroenterology 1996;110:21-9.
56. Coyle P, Philcox JC, Carey LC, Rofe AM. Metallothionein: the multipurpose protein. Cell Mol Life Sci 2002;59:627-47.
57. Karin M, Imbra RJ, Heguy A, Wong G. Interleukin 1 regulates metallothionein gene expression. Mol Cell Biol 1985;5:2866-9.
58. Funseth E, Pahlman M, Eloranta ML, Friman G, Ilback NG. Effects of coxsackievirus B3 infection on the acute-phase protein metallothionein and on cytochrome P-4501A1 involved in the detoxification processes of TCDD in the mouse. Sci Total Environ 2002;284:37-47.
59. Fukushima K, Ogawa H, Takahashi K, Naito H, Funayama Y, Kitayama T, et al. Non-pathogenic bacteria modulate colonic epithelial gene expression in germ-free mice. Scand J Gastroenterol 2003;38:626-34.
60. Tran CD, Huynh H, van den Berg M, van der Pas M, Campbell MA, Philcox JC, et al. Helicobacter-induced gastritis in mice not expressing metallothionein-1 and II. Helicobacter 2003;8:533-41.
61. Pfeiffer J, Guhl J, Waidner B, Kist M, Bereswill S. Magnesium uptake by CorA is essential for viability of the gastric pathogen Helicobacter pylori. Infect Immun 2002;70:3930-4.
62. Waidner B, Greiner S, Odenbreit S, Kavermann H, Velayudhan J, Stahler F, et al. Essential role of ferritin Pfr in Helicobacter pylori iron metabolism and gastric colonization. Infect Immun 2002;70:3923-9.
63. Delany I, Spohn G, Rappuoli R, Scarlato V. The Fur repressor controls transcription of iron-activated and -repressed genes in Helicobacter pylori. Mol Microbiol 2001;42:1297-309.
64. van Vliet AH, Poppelaars SW, Davies BJ, Stoof J, Bereswill S, Kist M. et al. NikR mediates nickel-responsive transcriptional induction of urease expression in Helicobacter pylori. Infect Immun 2002;70:2846-52.
65. Suzuki JS, Nishimura N, Zhang B, Nakatsuru Y, Kobayashi S, Satoh M, et al. Metallothionein deficiency enhances skin carcinogenesis induced by 7,12-dimethylbenz|a|antracene and 12-O-tetradecanoylphorbol-13-acetate in metallothionein-null mice. Carcinogenesis 2003;24:11232-2.
66. Forman D, Sitas F, Newall DG, Stacey AR, Boreham J, Peto R, et al. Geographic association of Helicobacter pylori antibody prevalence and gastric cancer mortality in rural China. Int J Cancer 1990;46:608-11.
67. Siurala M, Lehtola J, Ihamaki T. Atrophic gastritis and its sequelae. Results of 19-23 years' follow-up examinations. Scand J Gastroenterol 1974;9:441-6.
68. Negrini R, Lisato L, Zanella I, Poiesi C, Verardi R, Ghielmi S, et al. Helicobacter pylori infection induces antibodies cross-reacting with human gastric mucosa. Gastroenterology 1991; 1001:437-45.
69. Barrio R, Roldan MB, Alonso M, Canton R, Camarero C. Helicobacter pylori infection with parietal cell antibodies in children and adolescents with insulin dependent diabetes mellitus. J Pediatr Endocrinol Metab 1997;10:511-6.
70. Neu B, Randlkofer P, Neuhofer M, Voland P, Mayerhofer A, Gerhard M, et al. Helicobacter pylori induces apoptosis of rat gastric parietal cells. Am J Physiol Gastrointest Live Physiol 2002;283:G309-18.
71. Contreras M, Thiberge JM, Mandrand-Berthelot MA, Labigne A. Characterization of the roles of NikR, a nickel-responsive pleiotropic autoregulator of Helicobacter pylori. Mol Microbiol 2003;49:947-63.
72. Wolfram L, Bauerfeind P. Conserved low-affinity nickel-binding amino acids are essential for the function of the nickel permease NixA of Helicobacter pylori. J Bacterol.