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Volumn 274, Issue 5285, 1996, Pages 259-262

Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein

Author keywords

[No Author keywords available]

Indexed keywords

RNA; SIGNAL PEPTIDE; TREFOIL PEPTIDE;

EID: 10244252625     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.274.5285.259     Document Type: Article
Times cited : (470)

References (40)
  • 4
    • 0027918486 scopus 로고
    • M. Gajhede et al., Structure 1, 253 (1993); A. De et al., Proc. Natl. Acad. Sci. U.S.A. 91, 1084 (1994).
    • (1993) Structure , vol.1 , pp. 253
    • Gajhede, M.1
  • 6
    • 0023769895 scopus 로고
    • M. C. Rio et al., Science 241, 705 (1988); M. C. Rio et al., C. R. Acad. Sci. Paris 307, 825 (1988).
    • (1988) Science , vol.241 , pp. 705
    • Rio, M.C.1
  • 7
    • 0024207418 scopus 로고
    • M. C. Rio et al., Science 241, 705 (1988); M. C. Rio et al., C. R. Acad. Sci. Paris 307, 825 (1988).
    • (1988) C. R. Acad. Sci. Paris , vol.307 , pp. 825
    • Rio, M.C.1
  • 8
    • 0025607961 scopus 로고
    • N. Wright et al., J. Pathol. 162, 279 (1990); M. C. Rio et al., Gastroenterology 100, 375 (1991).
    • (1990) J. Pathol. , vol.162 , pp. 279
    • Wright, N.1
  • 9
    • 0026098726 scopus 로고
    • N. Wright et al., J. Pathol. 162, 279 (1990); M. C. Rio et al., Gastroenterology 100, 375 (1991).
    • (1991) Gastroenterology , vol.100 , pp. 375
    • Rio, M.C.1
  • 11
    • 0025784991 scopus 로고
    • J. A. Henry et al., Br. J. Cancer 64, 677 (1991); C. Welter et al., Lab. Invest. 66, 187 (1992).
    • (1991) Br. J. Cancer , vol.64 , pp. 677
    • Henry, J.A.1
  • 12
    • 0026513279 scopus 로고
    • J. A. Henry et al., Br. J. Cancer 64, 677 (1991); C. Welter et al., Lab. Invest. 66, 187 (1992).
    • (1992) Lab. Invest. , vol.66 , pp. 187
    • Welter, C.1
  • 15
    • 0028558892 scopus 로고
    • W. Hoffmann and F. Hauser, Trends Biol. Sci. 1B, 239 (1993); L. Thim, Digestion 55, 353 (1994).
    • (1994) Digestion , vol.55 , pp. 353
    • Thim, L.1
  • 16
    • 10244280075 scopus 로고    scopus 로고
    • note
    • An mpS2 cDNA probe (2) was used to isolate a 37-kb cosmid containing the mpS2 gene from a 129/Svj D3 ES cell genomic library (J. M. Gamier, Institut de Génétique et de Biologie Moléculaire et Cellulaire). A 7.1-kb Bam HI fragment containing the whole mpS2 gene was subcloned into pBluescript II SK+ (pBS) and sequenced.
  • 17
    • 10244271802 scopus 로고    scopus 로고
    • O. Lefebvre et al., data not shown
    • O. Lefebvre et al., data not shown.
  • 18
    • 0021017589 scopus 로고    scopus 로고
    • R. H. Riddell et al., Hum. Pathol. 14, 931 (1983); R.C. Haggitt, ibid. 25, 982 (1994). J. Rosaï, Ackerman's Surg. Pathol. 8, 632 (1996).
    • (1983) Hum. Pathol. , vol.14 , pp. 931
    • Riddell, R.H.1
  • 19
    • 0027993158 scopus 로고
    • R. H. Riddell et al., Hum. Pathol. 14, 931 (1983); R.C. Haggitt, ibid. 25, 982 (1994). J. Rosaï, Ackerman's Surg. Pathol. 8, 632 (1996).
    • (1994) Hum. Pathol. , vol.25 , pp. 982
    • Haggitt, R.C.1
  • 20
    • 0021017589 scopus 로고    scopus 로고
    • R. H. Riddell et al., Hum. Pathol. 14, 931 (1983); R.C. Haggitt, ibid. 25, 982 (1994). J. Rosaï, Ackerman's Surg. Pathol. 8, 632 (1996).
    • (1996) Ackerman's Surg. Pathol. , vol.8 , pp. 632
    • Rosaï, J.1
  • 21
    • 0028069666 scopus 로고
    • A. Panja, A. Barone, L. Mayer, J. Exp. Med. 179, 943 (1994); B. Rocha, D. Guy-Grand, P. Vassali, Curr. Opin. Immunol. 7, 235 (1995).
    • (1994) J. Exp. Med. , vol.179 , pp. 943
    • Panja, A.1    Barone, A.2    Mayer, L.3
  • 27
    • 10244280368 scopus 로고    scopus 로고
    • unpublished results
    • O. Lefebvre, unpublished results.
    • Lefebvre, O.1
  • 28
    • 0026337295 scopus 로고
    • R. A. Weinberg, Science 254, 1138 (1991); S. W. Lee, C. Tomasetto, R. Sager. Proc. Natl. Acad. Sci. U.S.A. 88, 2825 (1991); B. Vogelstein and W. Kinzler, Trends Genet. 9, 138 (1993); A.G. Knudson, Proc. Natl. Acad. Sci. U.S.A. 90, 10914 (1993); R. A. Weinberg, Cell 85, 457 (1996).
    • (1991) Science , vol.254 , pp. 1138
    • Weinberg, R.A.1
  • 29
    • 0025877670 scopus 로고
    • R. A. Weinberg, Science 254, 1138 (1991); S. W. Lee, C. Tomasetto, R. Sager. Proc. Natl. Acad. Sci. U.S.A. 88, 2825 (1991); B. Vogelstein and W. Kinzler, Trends Genet. 9, 138 (1993); A.G. Knudson, Proc. Natl. Acad. Sci. U.S.A. 90, 10914 (1993); R. A. Weinberg, Cell 85, 457 (1996).
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 2825
    • Lee, S.W.1    Tomasetto, C.2    Sager, R.3
  • 30
    • 0027401607 scopus 로고
    • R. A. Weinberg, Science 254, 1138 (1991); S. W. Lee, C. Tomasetto, R. Sager. Proc. Natl. Acad. Sci. U.S.A. 88, 2825 (1991); B. Vogelstein and W. Kinzler, Trends Genet. 9, 138 (1993); A.G. Knudson, Proc. Natl. Acad. Sci. U.S.A. 90, 10914 (1993); R. A. Weinberg, Cell 85, 457 (1996).
    • (1993) Trends Genet. , vol.9 , pp. 138
    • Vogelstein, B.1    Kinzler, W.2
  • 31
    • 0027504088 scopus 로고
    • R. A. Weinberg, Science 254, 1138 (1991); S. W. Lee, C. Tomasetto, R. Sager. Proc. Natl. Acad. Sci. U.S.A. 88, 2825 (1991); B. Vogelstein and W. Kinzler, Trends Genet. 9, 138 (1993); A.G. Knudson, Proc. Natl. Acad. Sci. U.S.A. 90, 10914 (1993); R. A. Weinberg, Cell 85, 457 (1996).
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 10914
    • Knudson, A.G.1
  • 32
    • 0029977751 scopus 로고    scopus 로고
    • R. A. Weinberg, Science 254, 1138 (1991); S. W. Lee, C. Tomasetto, R. Sager. Proc. Natl. Acad. Sci. U.S.A. 88, 2825 (1991); B. Vogelstein and W. Kinzler, Trends Genet. 9, 138 (1993); A.G. Knudson, Proc. Natl. Acad. Sci. U.S.A. 90, 10914 (1993); R. A. Weinberg, Cell 85, 457 (1996).
    • (1996) Cell , vol.85 , pp. 457
    • Weinberg, R.A.1
  • 35
    • 10244276030 scopus 로고    scopus 로고
    • note
    • The primers used were as follows (lowercase letters indicate restriction site; uppercase letters indicate mpS2-specifc sequence). RH1: 5′-ctggtacctttagat-CATCTGTGTGTTTGGATGC-3′, containing a Kpn I restriction site; RH2: 5′-ccatcgatagatctGCCACAATT-TATCCTCTC-3′, containing Cla I and BgI II restriction sites; RH3: 5′-agatcgatggatccATGGCCATCGAGAA-CAC-3′, containing Cla I and Bam HI restriction sites; RH4: 5′-ataggtacctctagaGGTGTGTATGTAGCAGG-3′, containing Kpn I and Xba I restriction sites. The P1 probe (C.36 kb) was generated by polymerase chain reaction (PCR) with the use ot a 5′ pBS primer and the 5′-TCAGCACACTGCTCACA-3′ (RH5) mpS2 primer; the P2 probe (0.3 kb) was a PmI I-Bam HI mpS2 fragment; and the mITF probe (420 bp) was isolated by reverse transcriptase PCR from mouse intestine RNA, with the use of the 5′-CCTGTGCAGTGGTCCT-GAAGC-3′ and 5′-AGCAATCAGATCAGCCTTGTG-3′ primers, derived from the mlTF cDNA sequence (16).
  • 37
    • 0025864268 scopus 로고
    • A. Gossler, T. Doetschman, R. Kom, Proc. Natl. Acad. Sci. U.S.A. 83, 9065 (1986); T. Lufkin, A. Dierich, M. LeMeur, Cell 65, 1105 (1991).
    • (1991) Cell , vol.65 , pp. 1105
    • Lufkin, T.1    Dierich, A.2    LeMeur, M.3
  • 38
    • 0023277545 scopus 로고
    • Total RNA was prepared from tissues frozen with liquid nitrogen, fractionated by agarose gel electrophoresis (1%) in the presence of formaldehyde, and transferred to nylon membranes (Hybond N; Amersham). P. Chomczynski and N. Sacchi, Anal. Bioehem. 162, 156 (1987).
    • (1987) Anal. Bioehem. , vol.162 , pp. 156
    • Hybond, N.1    Amersham2    Chomczynski, P.3    Sacchi, N.4
  • 39
    • 10244275181 scopus 로고    scopus 로고
    • note
    • The Ab502 polyclonal antibody is directed against a 30-amino acid synthetic peptide corresponding to the COOH-terminal half of mpS2.
  • 40
    • 10244276342 scopus 로고    scopus 로고
    • note
    • Supported by INSERM; CNRS; Centre Hospitalier Universitaire Régional; Mutuelle Générale de l'Enseignement National; Association pour la Recherche contre le Cancer; the Ligue Nationale Française contre le Cancer and Comité du Haut-Rhin, Fondation pour la Recherche Médicale Française, Fondation de France; and by a grant to P.C. from the Fondation Jeantet. O.L is the recipient of an IPSEN Foundation fellowship.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.