Human anti-human IL-18 antibody recognizing the IL-18-binding site 3 with IL-18 signaling blocking activity

Journal of Biochemistry

Volumn 138, Issue 4, 2005, Pages 433-442

  Hamasaki, Takayuki ^a   Hashiguchi, Shuhei ^a   Ito, Yuji ^a   Kato, Zenichiro ^b   Nakanishi, Kenji ^c,e   Nakashima, Toshihiro ^d   Sugimura, Kazuhisa ^a,e  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b GIFU UNIVERSITY   (Japan)

^c HYOGO COLLEGE OF MEDICINE   (Japan)

^d Chemo Sero Therapeutic Research Institute   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Allergy; Epitope mapping; Human antibody; Interleukin 18; Phage display

Indexed keywords

ALANINE; GAMMA INTERFERON; H18 108 ANTIBODY; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; INTERLEUKIN 18; INTERLEUKIN 18 ANTIBODY; INTERLEUKIN 18 RECEPTOR; INTERLEUKIN 18 RECEPTOR BETA; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

ALLERGY; ANTIBODY COMBINING SITE; ARTICLE; AUTOIMMUNE DISEASE; BINDING AFFINITY; BINDING SITE; CELL LINE; CYTOKINE PRODUCTION; EPITOPE MAPPING; FLOW CYTOMETRY; HUMAN; INFLAMMATION; INNATE IMMUNITY; PROTEIN EXPRESSION;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; ANTIBODY SPECIFICITY; BINDING SITES, ANTIBODY; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGIC TECHNIQUES; INTERFERON TYPE II; INTERLEUKIN-18; INTERLEUKIN-18 RECEPTOR ALPHA SUBUNIT; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-18; SIGNAL TRANSDUCTION;

EID: 28244497331     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/jb/mvi148     Document Type: Article

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