Generation and characterization of new monoclonal antibodies against human chymase

Hybridoma and Hybridomics

Volumn 23, Issue 4, 2004, Pages 237-243

  Kunori, Yuichi ^a   Hase, Naoki ^a   Kawamura, Takashi ^a   Sato, Hiroaki ^a   Kasai, Hidenori ^a   Muroga, Yumiko ^a   Kamimura, Takashi ^a   Fukamizu, Akiyoshi ^b  

^a TEIJIN PHARMA LIMITED   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHYMASE; EPITOPE; HYBRID PROTEIN;

ANIMAL CELL; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CLONING; CONTROLLED STUDY; DOT HYBRIDIZATION; ENZYME ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LOCALIZATION; HUMAN; HUMAN CELL; HUMAN VERSUS ANIMAL COMPARISON; HYBRIDOMA; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; SCREENING TEST; SPECIES DIFFERENCE; WESTERN BLOTTING;

ANTIBODIES, MONOCLONAL; BASE SEQUENCE; BLOTTING, WESTERN; CHYMASES; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; HUMANS; IMMUNOHISTOCHEMISTRY; SERINE ENDOPEPTIDASES;

ANIMALIA; RODENTIA;

EID: 4143110434     PISSN: 15368599     EISSN: None     Source Type: Journal    
DOI: 10.1089/1536859041651394     Document Type: Article

References (27)

1. Walls AF: Mast cell proteases in asthma. In: Inflammatory Mechanisms in Asthma. Holgate S. Busse W (Eds.). Marcel Dekker, New York, 1998, 89-110.
2. He S, and Walls AF: Human mast cell chymase induces the accumulation of neutrophils, eosinophils and other inflammatory cells in vivo. Br J Pharmacol 1998;125:1491-1500.
3. He S, and Walls AF: The induction of a prolonged increase in microvascular permeability by human mast cell chymase. Eur J Pharmacol 1998;352:91-98.
4. Kofford MW, Schwartz LB, Schechter NM, Yager DR, Diegelmann RF, and Graham MF: Cleavage of type I procollagen by human mast cell chymase initiates collagen fibril formation and generates a unique carboxyl-terminal propeptide. J Biol Chem 1997;272:7127-7131.
5. Mizutani H, Schechter N, Lazarus G, Black RA, and Kupper TS: Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase. J Exp Med 1991;174:821-825.
6. Tani K, Ogushi F, Kido H, Kawano T, Kunori Y, Kamimura T, Cui P, and Sone S: Chymase is a potent chemoattractant for human monocytes and neutrophils. J Leukoc Biol 2000;67:585-589.
7. Tunon de Lara JM, Okayama Y, McEuen AR, Heusser CH, Church MK, and Walls AF: Release and inactivation of interleukin-4 by mast cells. Ann NY Acad Sci 1994;725:50-58.
8. Varlio T, Seppa H, and Vaheri A: Susceptibility of soluble and matrix fibronectins to degradation by tissue proteinases, mast cell chymase and cathepsin G. J Biol Chem 1981;256:471-477.
9. Shiota N, Okunishi H, Fukamizu A, Sakonjo H, Kikumori M, Nishimura T, Nakagawa T, Murakami K, and Miyazaki M: Activation of two angiotensin-generating systems in the balloon-injured artery. FEBS Lett 1993;323:239-242.
10. Takai S, Shiota N, Kobayashi S, Matsumura E, and Miyazaki M: Induction of chymase that forms angiotensin II in the monkey atherosclerotic aorta. FEBS Lett 1997;412:86-90.
11. Urata H, Kinoshita A, Misono KS, Bumpus FM, and Husain A: Identification of a highly specific chymase as the major angiotensin 11-forming enzyme in the human heart. J Biol Chem 1990;265: 22348-22357.
12. Shiota N, Fukamizu A, Takai S, Okunishi H, Murakami K, and Miyazaki M: Activation of angiotensin II-forming chymase in the cardiomyopathic hamster heart. J Hypertens 1997;15:431-440.
13. Jin D, Takai S, Yamada M, Sakaguchi M, Yao Y, and Miyazaki M: Possible roles of cardiac chymase after myocardial infarction in hamster hearts. Jpn J Pharmacol 2001;86:203-214.
14. Taipale J, Lohi J, Saarinen J, Kovanen PT, and Keski-Oja J: Human mast cell chymase and leukocyte elastase release latent transforming growth factor-beta 1 from the extracellular matrix of cultured human epithelial and endothelial cells. J Biol Chem 1995;270:4689-4696.
15. Longley BJ, Tyrrell L, Ma Y, Williams DA, Halaban R, Langley K, Lu HS, and Schechter NM: Chymase cleavage of stem cell factor yields a bioactive, soluble product. Proc Natl Acad Sci USA 1997;94:9017-9021.
16. Irani AA, Schechter NM, Craig SS, DeBlois G, and Schwartz LB: Two types of human mast cells that have distinct neutral protease compositions. Proc Natl Acad Sci USA 1986;83:4464-4468.
17. Buckley MG, McEuen AR, and Walls AF: The detection of mast cell subpopulations in formalin-fixed human tissues using a new monoclonal antibody specific for chymase. J Pathol 1999;189:138-143.
18. Kunori Y, Koizumi M, Masegi T, Kasai H, Kawabata H, Yamazaki Y, and Fukamizu A: Rodent alpha-chymases are elastase-like proteases. Eur J Biochem 2002;269:5921-5930.
19. Kido H, Fukusen N, and Katsunuma N: A simple method for purification of chymase from rat tongue and rat peritoneal cells. Anal Biochem 1984;137:449-453.
20. Harlow E and Lane D: Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York. 1988.
21. Funahashi M, Matsumoto I, and Seno N: Preparation of three types of heparin-sepharose and their binding activities to thrombin and antithrombin III. Anal Biochem 1982;126:414-421.
22. Fureder W, Bankl HC, Toth J, Walchshofer S, Sperr W, Agis H, Semper H, Sillaber C, Lechner K, and Valent P: Immunophenotypic and functional characterization of human tonsillar mast cells. J Leukocyte Biol 1997;61:592-599.
23. Pereira PJ, Wang ZM, Rubin H, Huber R, Bode W, Schechter NM, and Strobl S: The 2.2 A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity. J Mol Biol 1999;286:163-173.
24. Caughey GH: Mast Cell Proteases in Immunology and Biology. Mercel Dekker, Basel, 1995.
25. Muramatsu M, Katada J, Hayashi I, and Majima, M: Chymase as a proangiogenic factor. A possible involvement of chymase-angiotensin-dependent pathway in the hamster sponge angiogenesis model. J Biol Chem 2000;275:5545-5552.
26. Shiota N, Jin D, Takai S, Kawamura T, Koyama M, Nakamura N, and Miyazaki M: Chymase is activated in the hamster heart following ventricular fibrosis during the chronic stage of hypertension. FEBS Lett 1997;406:301-304.
27. Hoshino F, Urata H, Inoue Y, Saito Y, Yahiro E, Ideishi M, Arakawa K, and Saku K: Chymase inhibitor improves survival in hamsters with myocardial infarction. J Cardiovasc Pharmacol 2003;41 (Suppl. 1):S11-S18.