-
1
-
-
18044394182
-
Interferons (IFNs) are key cytokines in both innate and adaptive antiviral immune responses-and viruses counteract IFN action
-
Bonjardim, C. A. 2005. Interferons (IFNs) are key cytokines in both innate and adaptive antiviral immune responses-and viruses counteract IFN action. Microbes Infect. 7: 569-578.
-
(2005)
Microbes Infect.
, vol.7
, pp. 569-578
-
-
Bonjardim, C.A.1
-
2
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
-
Alexopoulou, L., A. C. Holt, R. Medzhitov, and R. A. Flavell. 2001. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 413: 732-738.
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
3
-
-
1942485347
-
Toll-like receptors: Function and roles in lung disease
-
Basu, S., and M. J. Fenton. 2004. Toll-like receptors: function and roles in lung disease. Am. J. Physiol. 286: L887-L892.
-
(2004)
Am. J. Physiol.
, vol.286
-
-
Basu, S.1
Fenton, M.J.2
-
4
-
-
1642422416
-
Toll-like receptor 3: A link between Toll-like receptor, interferon and viruses
-
Matsumoto, M., K. Funami, H. Oshiumi, and T. Seya. 2004. Toll-like receptor 3: a link between Toll-like receptor, interferon and viruses. Microbiol. Immunol. 48: 147-154.
-
(2004)
Microbiol. Immunol.
, vol.48
, pp. 147-154
-
-
Matsumoto, M.1
Funami, K.2
Oshiumi, H.3
Seya, T.4
-
5
-
-
0038363463
-
Triggering the interferon antiviral response through an IKK-related pathway
-
Sharma, S., B. R. tenOever, N. Grandvaux, G. P. Zhou, R. Lin, and J. Hiscott. 2003. Triggering the interferon antiviral response through an IKK-related pathway. Science 300: 1148-1151.
-
(2003)
Science
, vol.300
, pp. 1148-1151
-
-
Sharma, S.1
Tenoever, B.R.2
Grandvaux, N.3
Zhou, G.P.4
Lin, R.5
Hiscott, J.6
-
6
-
-
0038393016
-
IKKε and TBK1 are essential components of the IRF3 signaling pathway
-
Fitzgerald, K. A., S. M. McWhirter, K. L. Faia, D. C. Rowe, E. Latz, D. T. Golenbock, A. J. Coyle, S. M. Liao, and T. Maniatis. 2003. IKKε and TBK1 are essential components of the IRF3 signaling pathway. Nat. Immunol. 4: 491-496.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 491-496
-
-
Fitzgerald, K.A.1
McWhirter, S.M.2
Faia, K.L.3
Rowe, D.C.4
Latz, E.5
Golenbock, D.T.6
Coyle, A.J.7
Liao, S.M.8
Maniatis, T.9
-
7
-
-
0035047145
-
Induction of IRF-3/-7 kinase and NF-κB in response to double-stranded RNA and virus infection: Common and unique pathways
-
Iwamura, T., M. Yoneyama, K. Yamaguchi, W. Suhara, W. Mori, K. Shiota, Y. Okabe, H. Namiki, and T. Fujita. 2001. Induction of IRF-3/-7 kinase and NF-κB in response to double-stranded RNA and virus infection: common and unique pathways. Genes Cells 6: 375-388.
-
(2001)
Genes Cells
, vol.6
, pp. 375-388
-
-
Iwamura, T.1
Yoneyama, M.2
Yamaguchi, K.3
Suhara, W.4
Mori, W.5
Shiota, K.6
Okabe, Y.7
Namiki, H.8
Fujita, T.9
-
8
-
-
0032926882
-
Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription
-
Lin, R., C. Heylbroeck, P. Genin, P. M. Pitha, and J. Hiscott. 1999. Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription. Mol. Cell. Biol. 19: 959-966.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 959-966
-
-
Lin, R.1
Heylbroeck, C.2
Genin, P.3
Pitha, P.M.4
Hiscott, J.5
-
9
-
-
0036467492
-
The interferon-α/β system in antiviral responses: A multimodal machinery of gene regulation by the IRF family of transcription factors
-
Taniguchi, T., and A. Takaoka. 2002. The interferon-α/β system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors. Curr. Opin. Immunol. 14: 111-116.
-
(2002)
Curr. Opin. Immunol.
, vol.14
, pp. 111-116
-
-
Taniguchi, T.1
Takaoka, A.2
-
10
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
-
Yamamoto, M., S. Sato, H. Hemmi, K. Hoshino, T. Kaisho, H. Sanjo, O. Takeuchi, M. Sugiyama, M. Okabe, K. Takeda, and S. Akira. 2003. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 301: 640-643.
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
Sanjo, H.6
Takeuchi, O.7
Sugiyama, M.8
Okabe, M.9
Takeda, K.10
Akira, S.11
-
11
-
-
0028332026
-
Double-stranded RNA-dependent protein kinase activates transcription factor NF-κB by phosphorylating IκB
-
Kumar, A., J. Haque, J. Lacoste, J. Hiscott, and B. R. Williams. 1994. Double-stranded RNA-dependent protein kinase activates transcription factor NF-κB by phosphorylating IκB. Proc. Natl. Acad. Sci. USA 91: 6288-6292.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 6288-6292
-
-
Kumar, A.1
Haque, J.2
Lacoste, J.3
Hiscott, J.4
Williams, B.R.5
-
12
-
-
0033257795
-
JNK2 and IKKβ are required for activating the innate response to viral infection
-
Chu, W. M., D. Ostertag, Z. W. Li, L. Chang, Y. Chen, Y. Hu, B. Williams, J. Perrault, and M. Karin, 1999. JNK2 and IKKβ are required for activating the innate response to viral infection. Immunity 11: 721-731.
-
(1999)
Immunity
, vol.11
, pp. 721-731
-
-
Chu, W.M.1
Ostertag, D.2
Li, Z.W.3
Chang, L.4
Chen, Y.5
Hu, Y.6
Williams, B.7
Perrault, J.8
Karin, M.9
-
13
-
-
0029051672
-
Involvement of the double-stranded-RNA-dependent kinase PKR in interferon expression and interferon-mediated antiviral activity
-
Der, S. D., and A. S. Lau. 1995. Involvement of the double-stranded-RNA- dependent kinase PKR in interferon expression and interferon-mediated antiviral activity. Proc. Natl. Acad. Sci. USA 92: 8841-8845.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8841-8845
-
-
Der, S.D.1
Lau, A.S.2
-
14
-
-
0033679958
-
Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection
-
Balachandran, S., P. C. Roberts, L. E. Brown, H. Truong, A. K. Pattnaik, D. R. Archer, and G. N. Barber. 2000. Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection. Immunity 13: 129-141.
-
(2000)
Immunity
, vol.13
, pp. 129-141
-
-
Balachandran, S.1
Roberts, P.C.2
Brown, L.E.3
Truong, H.4
Pattnaik, A.K.5
Archer, D.R.6
Barber, G.N.7
-
15
-
-
0034082457
-
PKR stimulates NF-κB irrespective of its kinase function by interacting with the IκB kinase complex
-
Bonnet, M. C., R. Weil, E. Dam, A. G. Hovanessian, and E. F. Meurs. 2000. PKR stimulates NF-κB irrespective of its kinase function by interacting with the IκB kinase complex. Mol. Cell. Biol. 20: 4532-4542.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 4532-4542
-
-
Bonnet, M.C.1
Weil, R.2
Dam, E.3
Hovanessian, A.G.4
Meurs, E.F.5
-
16
-
-
4444310098
-
Protein kinase R (PKR) interacts with and activates mitogen-activated protein kinase kinase 6 (MKK6) in response to double-stranded RNA stimulation
-
Silva, A. M., M. Whitmore, Z. Xu, Z. Jiang, X. Li, and B. R. Williams. 2004. Protein kinase R (PKR) interacts with and activates mitogen-activated protein kinase kinase 6 (MKK6) in response to double-stranded RNA stimulation. J. Biol. Chem. 279: 37670-37676.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 37670-37676
-
-
Silva, A.M.1
Whitmore, M.2
Xu, Z.3
Jiang, Z.4
Li, X.5
Williams, B.R.6
-
17
-
-
0347298789
-
PKR is not required for interferon-γ inhibition of VSV replication in neurons
-
Chesler, D. A., J. L. Muñoz-Jordán, N. Donelan, A. García-Sastre, and C. S. Reiss. 2003. PKR is not required for interferon-γ inhibition of VSV replication in neurons. Viral Immunol. 16: 87-96.
-
(2003)
Viral Immunol.
, vol.16
, pp. 87-96
-
-
Chesler, D.A.1
Muñoz-Jordán, J.L.2
Donelan, N.3
García-Sastre, A.4
Reiss, C.S.5
-
18
-
-
0035096556
-
Inhibition of porcine reproductive and respiratory syndrome virus by interferon-γ and recovery of virus replication with 2-aminopurine
-
Rowland, R. R., B. Robinson, J. Stefanick, T. S. Kim, L. Guanghua, S. R. Lawson, and D. A. Benfield. 2001. Inhibition of porcine reproductive and respiratory syndrome virus by interferon-γ and recovery of virus replication with 2-aminopurine. Arch. Virol. 146: 539-555.
-
(2001)
Arch. Virol.
, vol.146
, pp. 539-555
-
-
Rowland, R.R.1
Robinson, B.2
Stefanick, J.3
Kim, T.S.4
Guanghua, L.5
Lawson, S.R.6
Benfield, D.A.7
-
19
-
-
0027787072
-
2-Aminopurine inhibits the double-stranded RNA-dependent protein kinase both in vitro and in vivo
-
Hu, Y., and T. W. Conway. 1993. 2-Aminopurine inhibits the double-stranded RNA-dependent protein kinase both in vitro and in vivo. J. Interferon Res. 13: 323-328.
-
(1993)
J. Interferon Res.
, vol.13
, pp. 323-328
-
-
Hu, Y.1
Conway, T.W.2
-
20
-
-
28044445881
-
Proinflammatory cytokine responses induced by influenza a (H5N1) viruses in primary human alveolar and bronchial epithelial cells
-
Chan, M. C., C. Y. Cheung, W. H. Chui, S. W. Tsao, J. M. Nicholls, Y. O. Chan, R. W. Chan, H. T. Long, L. L. Poon, Y. Guan, and J. S. Peins. 2005. Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells. Respir. Res. 6: 135-147.
-
(2005)
Respir. Res.
, vol.6
, pp. 135-147
-
-
Chan, M.C.1
Cheung, C.Y.2
Chui, W.H.3
Tsao, S.W.4
Nicholls, J.M.5
Chan, Y.O.6
Chan, R.W.7
Long, H.T.8
Poon, L.L.9
Guan, Y.10
Peins, J.S.11
-
21
-
-
27744598497
-
Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: Functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice
-
Tumpey, T. M., A. García-Sastre, J. K. Taubenberger, P. Palese, D. E. Swayne, M. J. Pantin-Jackwood, S. Schultz-Cherry, A. Solórzano, N. Van Rooijen, J. M. Katz, and C. F. Basler. 2005. Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice. J. Virol. 79: 14933-14944.
-
(2005)
J. Virol.
, vol.79
, pp. 14933-14944
-
-
Tumpey, T.M.1
García-Sastre, A.2
Taubenberger, J.K.3
Palese, P.4
Swayne, D.E.5
Pantin-Jackwood, M.J.6
Schultz-Cherry, S.7
Solórzano, A.8
Van Rooijen, N.9
Katz, J.M.10
Basler, C.F.11
-
22
-
-
19944415600
-
Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: Possible relevance to pathogenesis
-
Cheung, C. Y., L. L. Poon, I. H. Ng, W. Luk, S. F. Sia, M. H. Wu, K. H. Chan, K. Y. Yuen, S. Gordon, Y. Guan, and J. S. Peiris. 2005. Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis. J. Virol. 79: 7819-7826.
-
(2005)
J. Virol.
, vol.79
, pp. 7819-7826
-
-
Cheung, C.Y.1
Poon, L.L.2
Ng, I.H.3
Luk, W.4
Sia, S.F.5
Wu, M.H.6
Chan, K.H.7
Yuen, K.Y.8
Gordon, S.9
Guan, Y.10
Peiris, J.S.11
-
23
-
-
0034231339
-
Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2
-
Farrar, J. D., J. D. Smith, T. L. Murphy, S. Leung, G. R. Stark, and K. M. Murphy. 2000. Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2. Nat. Immunol. 1: 65-69.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 65-69
-
-
Farrar, J.D.1
Smith, J.D.2
Murphy, T.L.3
Leung, S.4
Stark, G.R.5
Murphy, K.M.6
-
24
-
-
0032534672
-
The role of Stat4 in species-specific regulation of Th cell development by type I IFNs
-
Rogge, L., D. D'Ambrosio, M. Biffi, G. Penna, L. J. Minetti, D. H. Presky, L. Adorini, and F. Sinigaglia. 1998. The role of Stat4 in species-specific regulation of Th cell development by type I IFNs. J. Immunol. 161: 6567-6574.
-
(1998)
J. Immunol.
, vol.161
, pp. 6567-6574
-
-
Rogge, L.1
D'Ambrosio, D.2
Biffi, M.3
Penna, G.4
Minetti, L.J.5
Presky, D.H.6
Adorini, L.7
Sinigaglia, F.8
-
26
-
-
19944419799
-
Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs
-
Solórzano, A., R. J. Webby, K. M. Lager, B. H. Janke, A. García-Sastre, and J. A. Richt. 2005. Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs. J. Virol. 79: 7535-7543.
-
(2005)
J. Virol.
, vol.79
, pp. 7535-7543
-
-
Solórzano, A.1
Webby, R.J.2
Lager, K.M.3
Janke, B.H.4
García-Sastre, A.5
Richt, J.A.6
-
27
-
-
0345167006
-
A recombinant influenza a virus expressing an RNA-binding-defective NS1 protein induces high levels of β interferon and is attenuated in mice
-
Donelan, N. R., C. F. Basler, and A. García-Sastre. 2003. A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of β interferon and is attenuated in mice. J. Virol. 77: 13257-13266.
-
(2003)
J. Virol.
, vol.77
, pp. 13257-13266
-
-
Donelan, N.R.1
Basler, C.F.2
García-Sastre, A.3
-
28
-
-
0036628966
-
Viruses and the type I interferon antiviral system: Induction and evasion
-
Basler, C. F., and A. García-Sastre. 2002. Viruses and the type I interferon antiviral system: induction and evasion. Int. Rev. Immunol. 21: 305-337.
-
(2002)
Int. Rev. Immunol.
, vol.21
, pp. 305-337
-
-
Basler, C.F.1
García-Sastre, A.2
-
29
-
-
0036715591
-
Viruses and interferon: A fight for supremacy
-
Katze, M. G., Y. He, and M. Gale, Jr. 2002. Viruses and interferon: a fight for supremacy. Nat. Rev. Immunol. 2: 675-687.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 675-687
-
-
Katze, M.G.1
He, Y.2
Gale Jr., M.3
-
30
-
-
18844457095
-
Mechanisms of type-I- and type-II-interferon-mediated signalling
-
Platanias, L. C. 2005. Mechanisms of type-I- and type-II-interferon- mediated signalling. Nat. Rev. Immunol. 5: 375-386.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 375-386
-
-
Platanias, L.C.1
-
31
-
-
3142737286
-
Specific engagement of TLR4 or TLR3 does not lead to IFN-β-mediated innate signal amplification and STAT1 phosphorylation in resident murine alveolar macrophages
-
Punturieri, A., R. S. Alviani, T. Polak, P. Copper, J. Sonstein, and J. L. Curtis. 2004. Specific engagement of TLR4 or TLR3 does not lead to IFN-β-mediated innate signal amplification and STAT1 phosphorylation in resident murine alveolar macrophages. J. Immunol. 173: 1033-1042.
-
(2004)
J. Immunol.
, vol.173
, pp. 1033-1042
-
-
Punturieri, A.1
Alviani, R.S.2
Polak, T.3
Copper, P.4
Sonstein, J.5
Curtis, J.L.6
-
32
-
-
0037672694
-
Myeloid differentiation factor 88-dependent and -independent pathways in toll-like receptor signaling
-
Akira, S., and K. Hoshino. 2003. Myeloid differentiation factor 88-dependent and -independent pathways in toll-like receptor signaling. J. Infect. Dis. 187(Suppl. 2): S356-S363.
-
(2003)
J. Infect. Dis.
, vol.187
, Issue.SUPPL. 2
-
-
Akira, S.1
Hoshino, K.2
-
33
-
-
9144257930
-
Viral activation of macrophages through TLR-dependent and -independent pathways
-
Malmgaard, L., J. Melchjorsen, A. G. Bowie, S. C. Mogensen, and S. R. Paludan. 2004. Viral activation of macrophages through TLR-dependent and -independent pathways. J. Immunol. 173: 6890-6898.
-
(2004)
J. Immunol.
, vol.173
, pp. 6890-6898
-
-
Malmgaard, L.1
Melchjorsen, J.2
Bowie, A.G.3
Mogensen, S.C.4
Paludan, S.R.5
-
34
-
-
0036595049
-
Suppressors of cytokine signalling (SOCS) in the immune system
-
Alexander, W. S. 2002. Suppressors of cytokine signalling (SOCS) in the immune system. Nat. Rev. Immunol. 2: 410-416.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 410-416
-
-
Alexander, W.S.1
-
35
-
-
1542313914
-
Regulation of TLR signaling and inflammation by SOCS family proteins
-
Yoshimura, A., H. M. Ohishi, D. Aki, and T. Hanada. 2004. Regulation of TLR signaling and inflammation by SOCS family proteins. J. Leukocyte Biol. 75: 422-427.
-
(2004)
J. Leukocyte Biol.
, vol.75
, pp. 422-427
-
-
Yoshimura, A.1
Ohishi, H.M.2
Aki, D.3
Hanada, T.4
-
36
-
-
11144233242
-
Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells
-
Baetz, A., M. Frey, K. Heeg, and A. H. Dalpke. 2004. Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells. J. Biol. Chem. 279: 54708-54715.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 54708-54715
-
-
Baetz, A.1
Frey, M.2
Heeg, K.3
Dalpke, A.H.4
-
37
-
-
3042841621
-
SOCS-1 and SOCS-3 inhibit IFN-α-induced expression of the antiviral proteins 2,5-OAS and MxA
-
Vlotides, G., A. S. Sörensen, F. Kopp, K. Zitzmann, N. Cengic, S. Brand, R. Zachoval, and C. J. Auernhammer. 2004. SOCS-1 and SOCS-3 inhibit IFN-α-induced expression of the antiviral proteins 2,5-OAS and MxA. Biochem. Biophys. Res. Commun. 320: 1007-1014.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.320
, pp. 1007-1014
-
-
Vlotides, G.1
Sörensen, A.S.2
Kopp, F.3
Zitzmann, K.4
Cengic, N.5
Brand, S.6
Zachoval, R.7
Auernhammer, C.J.8
-
38
-
-
33744961633
-
NF-κB negatively regulates interferon-induced gene expression and anti-influenza activity
-
Wei, L., M. R. Sandbulte, P. G. Thomas, R. J. Webby, R. Homayouni, and L. M. Pfeffer. 2006. NF-κB negatively regulates interferon-induced gene expression and anti-influenza activity. J. Biol. Chem. 281: 11678-11684.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 11678-11684
-
-
Wei, L.1
Sandbulte, M.R.2
Thomas, P.G.3
Webby, R.J.4
Homayouni, R.5
Pfeffer, L.M.6
-
39
-
-
0034610181
-
IFNα/β promotes cell survival by activating NF-κB
-
Yang, C. H., A. Murti, S. R. Pfeffer, L. Basu, J. G. Kim, and L. M. Pfeffer. 2000. IFNα/β promotes cell survival by activating NF-κB. Proc. Natl. Acad. Sci. USA 97: 13631-13636.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13631-13636
-
-
Yang, C.H.1
Murti, A.2
Pfeffer, S.R.3
Basu, L.4
Kim, J.G.5
Pfeffer, L.M.6
-
40
-
-
0026780764
-
Two distinct pathways of interferon induction as revealed by 2-aminopurine
-
Daigneault, L., A. Haggarty, Q. H. Meng, and D. Skup. 1992. Two distinct pathways of interferon induction as revealed by 2-aminopurine. Nucleic Acids Res. 20: 2749-2754.
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 2749-2754
-
-
Daigneault, L.1
Haggarty, A.2
Meng, Q.H.3
Skup, D.4
|