SOCS-1 and SOCS-3 inhibit IFN-α-induced expression of the antiviral proteins 2,5-OAS and MxA

Biochemical and Biophysical Research Communications

Volumn 320, Issue 3, 2004, Pages 1007-1014

  Vlotides, George ^a   Sörensen, Astrid S ^a   Kopp, Florian ^a   Zitzmann, Kathrin ^a   Cengic, Neziha ^a   Brand, Stephan ^a   Zachoval, Reinhart ^a   Auernhammer, Christoph J ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

2 ,5 OAS; HepG2; IFN ; MxA; SOCS; STAT

Indexed keywords

ALPHA INTERFERON; JANUS KINASE; MYXOVIRUS RESISTANCE PROTEIN A; OLIGOADENYLATE SYNTHETASE; PROTEIN; STAT1 PROTEIN; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING; SUPPRESSOR OF CYTOKINE SIGNALING 1; SUPPRESSOR OF CYTOKINE SIGNALING 3; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANTIVIRAL ACTIVITY; ARTICLE; CELL CLONE; CELL STRAIN HEPG2; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

2',5'-OLIGOADENYLATE SYNTHETASE; ANTIVIRAL AGENTS; CARCINOMA, HEPATOCELLULAR; CARRIER PROTEINS; CELL LINE, TUMOR; GTP-BINDING PROTEINS; HUMANS; INTERFERON-ALPHA; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER NEOPLASMS; REPRESSOR PROTEINS; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANSCRIPTION FACTORS;

HEPATITIS C VIRUS;

EID: 3042841621     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.06.051     Document Type: Article

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