메뉴 건너뛰기




Volumn 23, Issue 4, 2003, Pages 1219-1227

Amino-acid residues involved in glutamate receptor 6 kainate receptor gating and desensitization

Author keywords

Binding site; Desensitization; Dimer; Glutamate receptor; Mutagenesis; S2 segment

Indexed keywords

AMINO ACID; AMPA RECEPTOR; GLUTAMATE 6 RECEPTOR; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR AGONIST; KAINIC ACID RECEPTOR; LEUCINE; LIGAND; TYROSINE; UNCLASSIFIED DRUG;

EID: 0037442510     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-04-01219.2003     Document Type: Article
Times cited : (64)

References (54)
  • 1
    • 0040355740 scopus 로고    scopus 로고
    • Agonist-induced isomerization in a glutamate receptor ligand-binding domain
    • Abele R, Keinanen K, Madden DR (2000) Agonist-induced isomerization in a glutamate receptor ligand-binding domain. J Biol Chem 275:21355-21363.
    • (2000) J Biol Chem , vol.275 , pp. 21355-21363
    • Abele, R.1    Keinanen, K.2    Madden, D.R.3
  • 2
    • 0033636314 scopus 로고    scopus 로고
    • Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: Crystal structures of the GluR2 ligand binding core
    • Armstrong N, Gouaux E (2000) Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron 28:165-181.
    • (2000) Neuron , vol.28 , pp. 165-181
    • Armstrong, N.1    Gouaux, E.2
  • 3
    • 0032578635 scopus 로고    scopus 로고
    • Structure of a glutamate-receptor ligand-binding core in complex with kainate
    • Armstrong N, Sun Y, Chen G-Q, Gouaux E (1998) Structure of a glutamate-receptor ligand-binding core in complex with kainate. Nature 395:913-917.
    • (1998) Nature , vol.395 , pp. 913-917
    • Armstrong, N.1    Sun, Y.2    Chen, G.-Q.3    Gouaux, E.4
  • 6
    • 0037088834 scopus 로고    scopus 로고
    • External anions and cations distinguish between AMPA and KA receptor gating mechanisms
    • Bowie D (2002) External anions and cations distinguish between AMPA and KA receptor gating mechanisms. J Physiol (Lond) 539:725-733.
    • (2002) J Physiol (Lond) , vol.539 , pp. 725-733
    • Bowie, D.1
  • 7
    • 0036582716 scopus 로고    scopus 로고
    • Functional stoichiometry of glutamate receptor desensitization
    • Bowie D, Lange GD (2002) Functional stoichiometry of glutamate receptor desensitization. J Neurosci 22:3392-3403.
    • (2002) J Neurosci , vol.22 , pp. 3392-3403
    • Bowie, D.1    Lange, G.D.2
  • 9
    • 0025765017 scopus 로고
    • Coning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA
    • Egebjerg J, Bettler R, Hermans-Borgmyer I, Heinemann S (1991) Coning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA. Nature 351:745-748.
    • (1991) Nature , vol.351 , pp. 745-748
    • Egebjerg, J.1    Bettler, R.2    Hermans-Borgmyer, I.3    Heinemann, S.4
  • 10
    • 0029917198 scopus 로고    scopus 로고
    • Pentameric subunit stoichiometry of a neuronal glutamate receptor
    • Ferrer-Montiel AV, Montal M (1996) Pentameric subunit stoichiometry of a neuronal glutamate receptor. Proc Natl Acad Sci USA 93:2741-2744.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2741-2744
    • Ferrer-Montiel, A.V.1    Montal, M.2
  • 11
    • 0037198702 scopus 로고    scopus 로고
    • RNA editing at Arg607 controls AMPA receptor exit from the endoplasmic reticulum
    • Greger IH, Khatri L, Ziff EB (2002) RNA editing at Arg607 controls AMPA receptor exit from the endoplasmic reticulum. Neuron 34:759-772.
    • (2002) Neuron , vol.34 , pp. 759-772
    • Greger, I.H.1    Khatri, L.2    Ziff, E.B.3
  • 12
    • 0029793180 scopus 로고    scopus 로고
    • Kinetics of homomeric GluR6 glutamate receptor channels
    • Heckmann M, Bufler J, Franke C, Dudel J (1996) Kinetics of homomeric GluR6 glutamate receptor channels. Biophys J 71:1743-1750.
    • (1996) Biophys J , vol.71 , pp. 1743-1750
    • Heckmann, M.1    Bufler, J.2    Franke, C.3    Dudel, J.4
  • 13
    • 0026530085 scopus 로고
    • The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related sub-units
    • Herb A, Burnashev N, Werner P, Sakmann B, Wisden W, Seeburg PH (1992) The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related sub-units. Neuron 8:775-785.
    • (1992) Neuron , vol.8 , pp. 775-785
    • Herb, A.1    Burnashev, N.2    Werner, P.3    Sakmann, B.4    Wisden, W.5    Seeburg, P.H.6
  • 16
    • 0022652797 scopus 로고
    • Excitatory amino acid receptors in hippocampus: Kainate fails to desensitize them
    • Kiskin NI, Krishtal OA, Tsyndrenko AY (1986) Excitatory amino acid receptors in hippocampus: kainate fails to desensitize them. Neurosci Lett 63:225-230.
    • (1986) Neurosci Lett , vol.63 , pp. 225-230
    • Kiskin, N.I.1    Krishtal, O.A.2    Tsyndrenko, A.Y.3
  • 17
    • 0028284469 scopus 로고
    • Mutational analysis of the glycine-binding site of the NMDA receptor: Structural similarity with bacterial amino acid-binding proteins
    • Kuryatov A, Laube B, Betz H, Kuhse J (1994) Mutational analysis of the glycine-binding site of the NMDA receptor: structural similarity with bacterial amino acid-binding proteins. Neuron 12:1291-1300.
    • (1994) Neuron , vol.12 , pp. 1291-1300
    • Kuryatov, A.1    Laube, B.2    Betz, H.3    Kuhse, J.4
  • 18
    • 0029583151 scopus 로고
    • Molecular dissection of the agonist binding site of an AMPA receptor
    • Kuusinen A, Arvola M, Keinanen K (1995) Molecular dissection of the agonist binding site of an AMPA receptor. EMBO J 14:6327-6332.
    • (1995) EMBO J , vol.14 , pp. 6327-6332
    • Kuusinen, A.1    Arvola, M.2    Keinanen, K.3
  • 19
    • 0032541434 scopus 로고    scopus 로고
    • AMPA receptors and bacterial periplasmic amino acid-binding proteins share the ionic mechanism of ligand recognition
    • Lampinen M, Pentikainen O, Johnson MS, Keinanen K (1998) AMPA receptors and bacterial periplasmic amino acid-binding proteins share the ionic mechanism of ligand recognition. EMBO J 17:4704-4711.
    • (1998) EMBO J , vol.17 , pp. 4704-4711
    • Lampinen, M.1    Pentikainen, O.2    Johnson, M.S.3    Keinanen, K.4
  • 20
    • 0032523002 scopus 로고    scopus 로고
    • Evidence for a tetrameric structure of recombinant NMDA receptors
    • Laube B, Kuhse J, Betz H (1998) Evidence for a tetrameric structure of recombinant NMDA receptors. J Neurosci 18:2954-2961.
    • (1998) J Neurosci , vol.18 , pp. 2954-2961
    • Laube, B.1    Kuhse, J.2    Betz, H.3
  • 22
    • 0032127530 scopus 로고    scopus 로고
    • Constraining ligand-binding site stoichiometry suggests that a cyclic nucleotide-gated channel is composed of two functional dimers
    • Liu DT, Tibbs GR, Paoletti P, Siegelbaum SA (1998) Constraining ligand-binding site stoichiometry suggests that a cyclic nucleotide-gated channel is composed of two functional dimers. Neuron 21:235-248.
    • (1998) Neuron , vol.21 , pp. 235-248
    • Liu, D.T.1    Tibbs, G.R.2    Paoletti, P.3    Siegelbaum, S.A.4
  • 25
    • 0032567729 scopus 로고    scopus 로고
    • A tetrameric subunit stoichiometry for a glutamate receptor-channel complex
    • Mano I, Teichberg VI (1998) A tetrameric subunit stoichiometry for a glutamate receptor-channel complex. NeuroReport 9:327-331.
    • (1998) NeuroReport , vol.9 , pp. 327-331
    • Mano, I.1    Teichberg, V.I.2
  • 26
    • 0029899637 scopus 로고    scopus 로고
    • A venus flytrap mechanism for activation and desensitization of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors
    • Mano I, Lamed Y, Teichberg VI (1996) A venus flytrap mechanism for activation and desensitization of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. J Biol Chem 27:15299-15302.
    • (1996) J Biol Chem , vol.27 , pp. 15299-15302
    • Mano, I.1    Lamed, Y.2    Teichberg, V.I.3
  • 27
    • 0035819074 scopus 로고    scopus 로고
    • Heteromeric AMPA receptors assemble with a preferred subunit stoichiometry and spatial arrangement
    • Mansour M, Nagarajan N, Nehring RB, Clements JD, Rosenmund C (2001) Heteromeric AMPA receptors assemble with a preferred subunit stoichiometry and spatial arrangement. Neuron 32:841-853.
    • (2001) Neuron , vol.32 , pp. 841-853
    • Mansour, M.1    Nagarajan, N.2    Nehring, R.B.3    Clements, J.D.4    Rosenmund, C.5
  • 28
    • 0025762715 scopus 로고
    • Determination of the subunit stoichiometry of a voltage-activated potassium channel
    • McKinnon R (1991) Determination of the subunit stoichiometry of a voltage-activated potassium channel. Nature 350:232-235.
    • (1991) Nature , vol.350 , pp. 232-235
    • McKinnon, R.1
  • 30
    • 0027235488 scopus 로고
    • Three-dimensional structures of the periplasmic lysine/arginine/ornithine-binding protein with and without a ligand
    • Oh BH, Pandit J, Kang CH, Nikaido K, Gokcen S, Ames GF, Kim SH (1993) Three-dimensional structures of the periplasmic lysine/arginine/ornithine-binding protein with and without a ligand. J Biol Chem 268:11348-11355.
    • (1993) J Biol Chem , vol.268 , pp. 11348-11355
    • Oh, B.H.1    Pandit, J.2    Kang, C.H.3    Nikaido, K.4    Gokcen, S.5    Ames, G.F.6    Kim, S.H.7
  • 32
    • 17144450204 scopus 로고    scopus 로고
    • Identification of the amino acid subsets accounting for the ligand binding specificity of a glutamate receptor
    • Paas Y, Eisenstein M, Medevielle F, Teihbert VI, Devillers-Thiery A (1996) Identification of the amino acid subsets accounting for the ligand binding specificity of a glutamate receptor. Neuron 17:979-990.
    • (1996) Neuron , vol.17 , pp. 979-990
    • Paas, Y.1    Eisenstein, M.2    Medevielle, F.3    Teihbert, V.I.4    Devillers-Thiery, A.5
  • 33
    • 0027715150 scopus 로고
    • Selective modulation of desensitization at AMPA versus kainate receptors by cyclothiazide and concanavalin A
    • Partin KM, Patneau DK, Winters CA, Mayer ML, Buonanno A (1993) Selective modulation of desensitization at AMPA versus kainate receptors by cyclothiazide and concanavalin A. Neuron 11:1069-1082.
    • (1993) Neuron , vol.11 , pp. 1069-1082
    • Partin, K.M.1    Patneau, D.K.2    Winters, C.A.3    Mayer, M.L.4    Buonanno, A.5
  • 34
    • 0027964227 scopus 로고
    • Cyclothiazide differentially modulates desensitization of α-amino-3-hydroxy-5-methyl-4-isoxazolepropronic acid receptor splice variants
    • Partin KM, Patneau DK, Mayer ML (1994) Cyclothiazide differentially modulates desensitization of α-amino-3-hydroxy-5-methyl-4-isoxazolepropronic acid receptor splice variants. Mol Pharmacol 46:129-138.
    • (1994) Mol Pharmacol , vol.46 , pp. 129-138
    • Partin, K.M.1    Patneau, D.K.2    Mayer, M.L.3
  • 35
    • 0029862192 scopus 로고    scopus 로고
    • AMPA receptor flip/flop mutants affecting deactivation, desensitization, and modulation by cyclothiazide, aniracitam, and thiocyanate
    • Partin KM, Fleck MW, Mayer ML (1996) AMPA receptor flip/flop mutants affecting deactivation, desensitization, and modulation by cyclothiazide, aniracitam, and thiocyanate. J Neurosci 16:6634-6647.
    • (1996) J Neurosci , vol.16 , pp. 6634-6647
    • Partin, K.M.1    Fleck, M.W.2    Mayer, M.L.3
  • 36
    • 0025852165 scopus 로고
    • Kinetic analysis of interactions between kainate and AMPA: Evidence for activation of a single receptor in mouse hippocampal neurons
    • Patneau DK, Mayer ML (1991) Kinetic analysis of interactions between kainate and AMPA: evidence for activation of a single receptor in mouse hippocampal neurons. Neuron 6:785-798.
    • (1991) Neuron , vol.6 , pp. 785-798
    • Patneau, D.K.1    Mayer, M.L.2
  • 37
    • 0027228511 scopus 로고
    • Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate
    • Patneau DK, Vyklicky L, Mayer NE (1993) Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate. J Neurosci 13:3496-3509.
    • (1993) J Neurosci , vol.13 , pp. 3496-3509
    • Patneau, D.K.1    Vyklicky, L.2    Mayer, N.E.3
  • 38
    • 0030722469 scopus 로고    scopus 로고
    • Stoichiometry of recombinant N-methyl-D-aspartate channels inferred from single-channel current patterns
    • Premkumar LS, Auerbach A (1997) Stoichiometry of recombinant N-methyl-D-aspartate channels inferred from single-channel current patterns. J Gen Physiol 110:485-502.
    • (1997) J Gen Physiol , vol.110 , pp. 485-502
    • Premkumar, L.S.1    Auerbach, A.2
  • 39
    • 0035426114 scopus 로고    scopus 로고
    • Subunit interactions and AMPA receptor desensitization
    • Robert A, Irizarry SN, Hughes TE, Howe JR (2001) Subunit interactions and AMPA receptor desensitization. J Neurosci 21:5574-5586.
    • (2001) J Neurosci , vol.21 , pp. 5574-5586
    • Robert, A.1    Irizarry, S.N.2    Hughes, T.E.3    Howe, J.R.4
  • 40
    • 0032486422 scopus 로고    scopus 로고
    • The tetrameric structure of a glutamate receptor channel
    • Rosenmund C, Stern-Bach Y, Stevens CF (1998) The tetrameric structure of a glutamate receptor channel. Science 280:1596-1599.
    • (1998) Science , vol.280 , pp. 1596-1599
    • Rosenmund, C.1    Stern-Bach, Y.2    Stevens, C.F.3
  • 41
    • 0026555294 scopus 로고
    • Primary structure and expression of the subunit of the glutamate receptor channel selective for kainate
    • Sakimura K, Morita T, Kushiya E, Mishna M (1992) Primary structure and expression of the subunit of the glutamate receptor channel selective for kainate. Neuron 8:267-274.
    • (1992) Neuron , vol.8 , pp. 267-274
    • Sakimura, K.1    Morita, T.2    Kushiya, E.3    Mishna, M.4
  • 42
    • 0027282808 scopus 로고
    • The molecular biology of mammalian glutamate receptors
    • Seeburg PH (1993) The molecular biology of mammalian glutamate receptors. Trends Pharmacol 14:297-303.
    • (1993) Trends Pharmacol , vol.14 , pp. 297-303
    • Seeburg, P.H.1
  • 43
    • 0030755886 scopus 로고    scopus 로고
    • A novel allosteric potentiator of AMPA receptors: 4-[2-(phenylsulfonylamino)ethylthio]-2,6-difluoro-phenoxyacetamide
    • Sekiguchi M, Fleck MW, Mayer ML, Takeo J, Chiba Y, Yamashita S, Wada K (1997) A novel allosteric potentiator of AMPA receptors: 4-[2-(phenylsulfonylamino)ethylthio]-2,6-difluoro-phenoxyacetamide. J Neurosci 17: 5760-5771.
    • (1997) J Neurosci , vol.17 , pp. 5760-5771
    • Sekiguchi, M.1    Fleck, M.W.2    Mayer, M.L.3    Takeo, J.4    Chiba, Y.5    Yamashita, S.6    Wada, K.7
  • 44
    • 0033623299 scopus 로고    scopus 로고
    • Concentration-dependent substate behavior of native AMPA receptors
    • Smith TC, Howe JR (2000) Concentration-dependent substate behavior of native AMPA receptors. Nat Neurosci 3:992-997.
    • (2000) Nat Neurosci , vol.3 , pp. 992-997
    • Smith, T.C.1    Howe, J.R.2
  • 45
    • 0028559605 scopus 로고
    • Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins
    • Stern-Bach Y, Bettler B, Hartley M, Sheppard PO, O'Hara PJ, Heinemann SF (1994) Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins. Neuron 13:1345-1357.
    • (1994) Neuron , vol.13 , pp. 1345-1357
    • Stern-Bach, Y.1    Bettler, B.2    Hartley, M.3    Sheppard, P.O.4    O'Hara, P.J.5    Heinemann, S.F.6
  • 46
    • 0032191104 scopus 로고    scopus 로고
    • A point mutation in the glutamate binding site blocks desensitization of AMPA receptors
    • Stern-Bach Y, Russo S, Neuman M, Rosemund C (1998) A point mutation in the glutamate binding site blocks desensitization of AMPA receptors. Neuron 21:907-918.
    • (1998) Neuron , vol.21 , pp. 907-918
    • Stern-Bach, Y.1    Russo, S.2    Neuman, M.3    Rosemund, C.4
  • 48
    • 0030777076 scopus 로고    scopus 로고
    • Identification of amino acid residues that control functional behavior in GluR5 and GluR6 kainate receptors
    • Swanson GT, Gereau IV RW, Green T, Heinemann SF (1997) Identification of amino acid residues that control functional behavior in GluR5 and GluR6 kainate receptors. Neuron 19:913-926.
    • (1997) Neuron , vol.19 , pp. 913-926
    • Swanson, G.T.1    Gereau R.W. IV2    Green, T.3    Heinemann, S.F.4
  • 50
    • 0033025560 scopus 로고    scopus 로고
    • Evidence for dimerization ofdimers in K+ channel assembly
    • Tu LW, Deutsch C (1999) Evidence for dimerization ofdimers in K+ channel assembly. Biophys J 76:2004-2017.
    • (1999) Biophys J , vol.76 , pp. 2004-2017
    • Tu, L.W.1    Deutsch, C.2
  • 51
    • 0028964302 scopus 로고
    • The importance of two specific domains in ligand binding to the AMPA/kainate glutamate receptors GluR2 and GluR6
    • Tygesen CK, Jorgensen M, Andersen PH (1995) The importance of two specific domains in ligand binding to the AMPA/kainate glutamate receptors GluR2 and GluR6. FEBS Lett 363:184-188.
    • (1995) FEBS Lett , vol.363 , pp. 184-188
    • Tygesen, C.K.1    Jorgensen, M.2    Andersen, P.H.3
  • 53
    • 0027237599 scopus 로고
    • Differential modulation by cyclothiazide and concanavalin A of desensitization at native α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid- and kainate-preferring glutamate receptors
    • Wong LA, Mayer ML (1993) Differential modulation by cyclothiazide and concanavalin A of desensitization at native α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid- and kainate-preferring glutamate receptors. Mol Pharmacol 44:504-510.
    • (1993) Mol Pharmacol , vol.44 , pp. 504-510
    • Wong, L.A.1    Mayer, M.L.2
  • 54
    • 0027209412 scopus 로고
    • Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents
    • Yamada KA, Tang C-M (1993) Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents. J Neurosci 13:3904-3915.
    • (1993) J Neurosci , vol.13 , pp. 3904-3915
    • Yamada, K.A.1    Tang, C.-M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.