The role of mutation frequency decline and SOS repair systems in methyl methanesulfonate mutagenesis

Acta Biochimica Polonica

Volumn 45, Issue 2, 1998, Pages 523-533

  Grzesiuk, Elzbieta ^a  

^a INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

Author keywords

DNA alkylation; DNA repair; Escherichia coli; Methyl methanesulfonate; Mutation frequency decline; SOS response; umuDC

Indexed keywords

ESCHERICHIA COLI;

MESYLIC ACID METHYL ESTER; MUTAGENIC AGENT;

ANIMAL; DNA REPAIR; ESCHERICHIA COLI; MUTAGENESIS; MUTATION; REVIEW;

ANIMALS; DNA REPAIR; ESCHERICHIA COLI; METHYL METHANESULFONATE; MUTAGENESIS; MUTAGENS; MUTATION;

EID: 0032244638     PISSN: 0001527X     EISSN: None     Source Type: Journal    
DOI: 10.18388/abp.1998_4245     Document Type: Review

References (60)

1. Singer, B. & Grunberger, D. (1983) Molecular Biology of Mutagens and Carcinogens; pp. 1-347, Plenum, New York.
2. Frei, J.V., Swenson, D.H., Warren, W. & Lawley, P.D. (1978) Alkylation of deoxyribonucleic acid in vivo in various organs of C57B1 mice by the carcinogens TV-methyl-N-nitrosourea, N-ethyk-N-nitrosourea and ethyl methanesulfonate in relation to induction of thymic lymphoma. Biochem. J. 174, 1031-1044.
3. Singer, B. (1976) All oxygens in nucleic acids react with carcinogenic ethylating agents. Nature 264, 333-339.
4. Lawley, P.D. (1984) Carcinogenesis by alkylating agents; in Chemical Cartinogenesis (Searle, C.E., ed.) ACS Monograph 182, pp. 325-484, American Chemical Society Washington.
5. N2 reaction mechanisms, explains why carcinogenic alkylating agents can form different proportions of adducts at oxygen versus nitrogen in DNA. Chem. Res. Toxicol. 7, 277-280.
6. 6 of guanine as a site of methylation. Biochem. J. 116, 693-707.
7. Janion, C. (1995) Mechanisms of action of methyl methanesulfonate on Escherichia coli: Mutagenesis, DNA damage and repair. Adv. Biochem. 41, 308-313.
8. 6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents. Cancer Invest. 2, 223-231.
9. Tudek, B., Boiteux, S. & Laval, J. (1992) Biological properties of imidazole ring-open N7 methyl-guanine in M13mp18 phage DNA. Nucleic Acids Res. 20, 3079-3084.
10. Boiteux, S. & Laval, J. (1983) Imidazole ring-opened guanine: An inhibitor of DNA synthesis. Biochem. Biophys. Res. Commun. 110, 625-631.
11. Foster, P.L. & Eisenstadt, E. (1985) Induction of transversion mutations in Escherichia coli by N-methyl-N-nitrosoguanidine is SOS dependent. J. Bacteriol. 163, 213-220.
12. Sledziewska-Gójska, E. & Janion, C. (1989) Alternative pathways of methyl methanesulfonate-induced mutagenesis in Escherichia coli. Molec. Gen. Genet. 216, 126-131.
13. Grzesiuk, E. & Janion, C. (1994) The frequency of MMS-induced, umuDC-dependent, mutation declines during starvation in Escherichia coli. Molec. Gen. Genet. 245, 486-492.
14. 6-methylguanine built into a unique site in a viral genome. Proc. Natl, Acad. Sci. U.S.A. 81, 6271-6275.
15. Śledziewska-Gójska, E., Grzesiuk, E., Płachta, A., Janion, C. (1992) Mutagenesis of Escherichia coli: A method of determining mutagenic specificity by analysis of tRNA supressors. Mutagenesis 7, 41-46.
16. van Zeeland, A.A. (1988) Molecular dosimetry of alkylating agents: Quantitative comparison of genetic effects on the basis of DNA adduct formation. Mutagenesis 3, 179-191.
17. + revertants. Mutation Res. 62, 227-237.
18. Kato, T., Shinoura, Y., Templin, A., Clark, A.J. (1980) Analysis of ultraviolet lightinduced suppressor mutation in the strain of Escherichia coli K12 AB1157. An application for molecular mechanism of UV mutagenesis. Molec. Gen. Genet. 180, 283-291.
19. Shinoura, Y., Kato, T., Glickman, B.W. (1983) A rapid and simple method for the determination of base substitution and frameshift specificity of mutagens. Mutation Res. 111, 43-49.
20. Sargentini, N.J. & Smith, K.C. (1989) Mutational spectrum analysis of umuC-independent and umuC-dependent-radiation mutagenesis in Escherichia coli. Mutation Res. 211, 193-203.
21. Janion, C. & Grzesiuk, E. (1990) Effect of umuC on EMS-induced mutagenesis in Escherichia coli deficient in mismatch repair; in Mutation and Environment (Mendelsohn, M.L. & Albertini, R.J., eds.) Part A, pp. 145-153, Wiley-Liss, New York.
22. Witkin, E.M. (1956) Time, temperature and protein synthesis: A study of ultraviolet-induced mutation in bacteria. Cold Spring Harbor Symp. Quant. Biol. 21, 123-140.
23. Bockrath, R.C. & Palmer, J.E. (1977) Differential repair of premutational UV-lesion of tRNA genes in E. coli. Molec. Gen. Genet. 156, 133-140.
24. Mellon, I., Spivak, G. & Hanawalt, P.C. (1987) Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene. Cell 51, 241-249.
25. Selby, C.P. & Sancar, A. (1990) Transcription preferentially inhibits nucleotide excision repair of the template DNA strand in vitro. J. Biol. Chem. 265, 58-63.
26. Selby, C.P., Witkin, E.M. & Sancar, A. (1991) Escherichia coli mfd mutant deficient in "Mutation Frequency Decline" lacks strand-specific repair: in vitro complementation with purified coupling factor. Proc. Natl. Acad. Sci. U.S.A. 88, 11574-11578.
27. Witkin, E.M. (1969) Ultraviolet-induced mutation and DNA repair. Annu. Rev. Microbiol. 23, 487-514.
28. Selby, C.P. & Sancar, A. (1994) Mechanisms of transcription-repair coupling and mutation frequency decline. Microbiol. Rev. 58, 317-327.
29. Grzesiuk, E. & Janoin, C. (1996) MMS-induced mutagenesis and DNA repair in Escherichia coli dnaQ49: Contribution of UmuD' to DNA repair. Mutation Res. 362, 147-154.
30. Sweder, K.S., Verhage, R.A., Crowley, D.J., Crouse, G.F., Brouwer, J., Hanawalt, P.C. (1996) Mismatch repair mutants in yeast are not defective in transcription-coupled DNA repair of UV-induced DNA damage. Genetics 143, 1127-1137.
31. Mellon, I. & Champe, G.N. (1996) Products of DNA mismatch repair genes mutS and mutL are required for transcription-coupled nucleotide excision repair of the lactose operon in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 93, 1292-1297.
32. Li, B.H. & Bockrath, R.C. (1995) Mutation frequency decline in Escherichia coli. I. Effects of defects in mismatch repair. Molec. Gen. Genet. 249, 585-590.
33. Grzesiuk, E. & Janion, C. (1998) Mutation frequency decline in MMS-treated E. coli K12 mutS strains. Mutagenesis 13, 127-132.
34. Lindahl, T., Sedgwick, B., Sekiguchi, M., Nakabeppu, Y. (1988) Regulation and expression of adaptive response to alkylating agents. Annu. Rev. Biochem. 57, 133-157.
35. Friedberg, E.G., Walker, G., Siede, W. (1995) Nucleotide exision repair in procaryotes; in DNA Repair and Mutagenesis (Friedberg, E.C., Walker, G. & Siedge, W., eds.) pp. 191-225, ASM Press, Washington.
36. de Oliveira, R.C., Laval, J. & Boiteux, S. (1986) Induction of SOS and adaptive responses by alkylating agents in Escherichia coli mutants deficient in 3-methyladenine-DNA glycosylase activities. Mutation Res. 183, 11-20.
37. Radman, M. (1974) Phenomenology of an inducible mutagenic pathway in Escherichia coli: SOS repair hypothesis; in Molecular and Environmental Aspects of Mutagenesis (Prakash, L., Scherman, F., Miller, M., Lawrence, C. & Tabor, H.W., eds.) vol. 3, pp. 128-142, Charles C. Thomas Publisher, Springfield.
38. Little, J.W. & Mount, D.W. (1982) The SOS regulatory system of E. coli. Cell 29, 11-22.
39. Little, J.W. (1983) The SOS regulatory system: Control of its state by the level of RecA protease. J. Mol Biol. 167, 791-808.
40. Sommer, S., Knezevic, J., Bailone, A., Devoret, R. (1993) Induction of only one SOS operon, umuDC, is required for SOS mutagenesis in Escherichia coli. Molec. Gen. Genet. 239, 137-144.
41. Levis, L.K., Harlow, G.R., Gregg-Jolly, L.A., Mount, D.W. (1994) Identification of high affinity binding sites for LexA which define new DNA damage-inducible genes in Escherichia coli. J. Mol Biol. 241, 507-523.
42. Bridges, B.A. & Woodgate, R. (1985) The two-step model of bacterial UV mutagenesis. Mutation Res. 150, 133-139.
43. Bridges, B.A. & Woodgate, R. (1985) Mutagenic repair in Escherichia coli: Products of the recA gene and of the umuD and umuC genes act at different steps in UV-mutagenesis. Proc. Natl. Acad. Sci. U.S.A. 82, 4193-4197.
44. Rajagopalan, M., Lu, C., Woodgate, R., O'Donnell, M., Goodman, M.F. & Echols, H. (1992) Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replication bypass of an abasic DNA lesion by DNA polymerase III. Proc. Natl. Acad. Sci. U.S.A. 89, 10777-10781.
45. Hagenesee, M.E., Timme, T., Bryan, S.K. & Moses, R.E. (1987) DNA polimerase III of Escherichia coli is required for UV and ethyl methanesulfonate mutagenesis. Proc. Natl. Acad. Sci. U.S.A. 84, 4195-4199.
46. Kitagawa, Y., Akaboshi, E., Shinagawa, H., Horii, T., Ogawa, H. & Kato, T. (1985) Structural analysis of the umu operon required for inducible mutagenesis in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 82, 4336-4340.
47. Woodgate, R. & Levine, A.S. (1996) Damage Inducible Mutagenesis: Recent Insights into the activities of the Umu family of mutagenesis proteins; in Cancer Surveys, Genetic Instability in Cancer; vol. 28, pp. 117-136, Imp. Canc. Res. Fund.
48. Burckhardt, S.E., Woodgate, R., Scheuermann, R.H. & Echols, H. (1988) UmuD mutagenesis protein in Escherichia coli: Overproduction, purification, and cleavage by RecA. Proc. Natl. Acad. Sci. U.S.A. 85, 1811-1815.
49. Woodgate, R., Rajagopalan, M., Lu, C. & Echols, H. (1989) UmuC mutagenesis protein in Escherichia coli: Purification and interaction with UmuD and UmuD'. Proc. Natl. Acad. Sci. U.S.A. 86, 7301-7305.
50. Battista, J.R., Ohta, T., Nohmi, T., Sun, W. & Walker, G.C. (1990) Dominant negative umuD mutations decreasing RecA-mediated cleavage suggest roles for intact UmuD in modulation of SOS mutagenesis. Proc. Natl. Acad. Sci. U.S.A. 87, 7190-7194.
51. Bruck, I., Woodgate, R., McEntee, K. & Goodman, M.F. (1996) Purification of a soluble UmuD'C complex from Escherichia coli: Cooperative binding of UmuD'C to single-stranded DNA. J. Biol. Chem. 271, 10767-10774.
52. Petit, M.A., Bedale, W., Osipiuk, J., Lu, C., Rajagopalan, M., McInerney, P., Goodman, M.F. & Echols, H. (1994) Sequential folding of UmuC by the Hsp70 and Hsp60 chaperone complexes of Escherichia coli. J. Biol Chem. 269, 23824-23849.
53. Peat, T.S., Frank, E.G., McDonald, J.P., Levine, A.S., Woodgate, R. & Hendrickson, W.A. (1996) Structure of the UmuD' protein and its regulation in the response to DNA damage. Nature 380, 727-730.
54. Sweasy, J.B., Witkin, E.M., Sinha, N. & Roegner-Maniscalco, V. (1990) RecA protein of Escherichia coli has a third essential role in SOS mutator activity. J. Bacteriol. 172, 3030-3036.
55. Bailone, A., Sommer, S., Knezevic, J., Dutreix, M. & Devoret, R. (1991) A RecA protein mutant deficient in its interaction with the UmuDC complex. Biochimie 73, 471-478.
56. Bridges, B.A., Mottershead, R.P. & Sedgwick, S.G. (1976) Mutagenic repair in Escherichia coli, III. Requirement for a function of DNA polimerase III in ultraviolet light mutagenesis. Molec. Gen. Genet. 144, 53-58.
57. Woodgate, R., Bridges, B.A., Herrera, G. & Blanco, M. (1987) Mutagenic repair in Escherichia coli. XIII, Proofreading exonuclease of DNA polymerase III holoenzyme is not operational during UV mutagenesis. Mutation Res. 183, 31-37.
58. Woodgate, R., Singh, M., Kulaeva, O.I., Frank, E.G., Levine, A.S. & Koch, W.H. (1994) Isolation and characterization of novel plasmid-encoded umuC mutants. J. Bacteriol. 176, 5011-5021.
59. Schendel, P.F. & Defais, M. (1980) The role of umuC gene product in mutagenesis by simple alkylating agents. Molec. Gen. Genet. 177, 661-665.
60. Grzesiuk, E. & Janion, C. (1993) Some aspects of EMS-induced mutagenesis in Escherichia coli. Mutation Res. 297, 313-321.