Oncogenicity evaluation of resveratrol in p53(±) (p53 knockout) mice

Food and Chemical Toxicology

Volumn 45, Issue 1, 2007, Pages 55-63

  Horn, T L ^a   Cwik, M J ^a   Morrissey, R L ^b   Kapetanovic, I ^c   Crowell, J A ^c   Booth, T D ^d   McCormick, D L ^a  

^a IIT RESEARCH INSTITUTE   (United States)

^b Pathology Associates   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d Royalmount Pharma   (Canada)

Author keywords

Cancer chemopreventive agent; Oncogenicity; p53( ) mouse; Resveratrol

Indexed keywords

4 CRESIDINE; ANILINE DERIVATIVE; CARCINOGEN; CHOLESTEROL; PROTEIN P53; RESVERATROL; RESVERATROL GLUCURONIDE; RESVERATROL SULFATE; UNCLASSIFIED DRUG;

ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BENIGN TUMOR; BLADDER CANCER; BLADDER DISEASE; BLOOD TOXICITY; BODY WEIGHT; CANCER INCIDENCE; CARCINOGEN TESTING; CHOLESTEROL BLOOD LEVEL; CLINICAL FEATURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG CARCINOGENICITY; DRUG EXPOSURE; DRUG MEGADOSE; EPITHELIUM HYPERPLASIA; FEEDING; FOOD; FOOD INTAKE; GASTROINTESTINAL TRACT; GRAPE; GROUPS BY SEX; HEMATOLOGIC DISEASE; HISTOPATHOLOGY; HYDRONEPHROSIS; KNOCKOUT MOUSE; LIVER WEIGHT; LOW DRUG DOSE; MALIGNANT NEOPLASTIC DISEASE; MAXIMUM TOLERATED DOSE; MORTALITY; MOUSE; NEPHROTOXICITY; NONHUMAN; SURVIVAL; TARGET ORGAN; WEIGHT GAIN;

ADMINISTRATION, ORAL; ANEMIA; ANILINE COMPOUNDS; ANIMALS; ANTICARCINOGENIC AGENTS; CARCINOGENICITY TESTS; CARCINOGENS; CHEMOPREVENTION; CHOLESTEROL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HYDRONEPHROSIS; KIDNEY; LIVER; LONGEVITY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORGAN SIZE; STILBENES; TUMOR SUPPRESSOR PROTEIN P53; URINARY BLADDER;

VITACEAE;

EID: 33751209800     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2006.07.015     Document Type: Article

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