Roles of necrosis, apoptosis, and mitochondrial dysfunction in S-(1,2-dichlorovinyl)-L-cysteine sulfoxide-induced cytotoxicity in primary cultures of human renal proximal tubular cells

Journal of Pharmacology and Experimental Therapeutics

Volumn 305, Issue 3, 2003, Pages 1163-1172

  Lash, Lawrence H ^a   Putt, David A ^a   Hueni, Sarah E ^a   Krause, Renee J ^b   Elfarra, Adnan A ^b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE DERIVATIVE; DIMETHYLANILINE MONOOXYGENASE; ENZYME INHIBITOR; GLUTATHIONE; S (1,2 DICHLOROVINYL)CYSTEINE SULFOXIDE; SULFOXIDE; THIAMAZOLE; TRICHLOROETHYLENE; UNCLASSIFIED DRUG;

ADULT; AGED; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; HUMAN; HUMAN CELL; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; MALE; METABOLISM; MITOCHONDRION; NORMAL HUMAN; POLLUTANT; PRIORITY JOURNAL; PROTECTION; TIME;

APOPTOSIS; CELL SIZE; CELL SURVIVAL; CYSTEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; HUMANS; KIDNEY TUBULES, PROXIMAL; L-LACTATE DEHYDROGENASE; MITOCHONDRIA; NECROSIS; SULFOXIDES;

EID: 0038137502     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.046185     Document Type: Article

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