Unexpected link between iron and drug resistance of Candida spp.: Iron depletion enhances membrane fluidity and drug diffusion, leading to drug-susceptible cells

Antimicrobial Agents and Chemotherapy

Volumn 50, Issue 11, 2006, Pages 3597-3606

  Prasad, Tulika ^a   Chandra, Aparna ^a   Mukhopadhyay, Chinmay K ^a   Prasad, Rajendra ^a  

^a JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANISOMYCIN; CYCLOHEXIMIDE; ERGOSTEROL; FLUCONAZOLE; FUNGAL PROTEIN; IRON; NYSTATIN; PROTEIN CDR1P; PROTEIN CDR2P; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM CULTURE; CANDIDA; CANDIDA ALBICANS; CONTROLLED STUDY; CULTURE MEDIUM; DOWN REGULATION; DRUG DIFFUSION; ERG11 GENE; FLUORESCENCE POLARIZATION; FTR1 GENE; FTR2 GENE; FUNGAL GENE; GENE MUTATION; IRON DEPLETION; IRON TRANSPORT; MEMBRANE FLUIDITY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL;

ANTIFUNGAL AGENTS; CANDIDA; COPPER; CULTURE MEDIA; DIFFUSION; DOWN-REGULATION; DRUG RESISTANCE, FUNGAL; DRUG SYNERGISM; ERGOSTEROL; FLUCONAZOLE; FLUORESCENCE POLARIZATION IMMUNOASSAY; GENOTYPE; HYBRIDIZATION, GENETIC; IRON; IRON CHELATING AGENTS; MEMBRANE FLUIDITY; MICROBIAL SENSITIVITY TESTS; RNA, FUNGAL;

EID: 33750601648     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00653-06     Document Type: Article

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