-
1
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
Saltiel AR, Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism. Nature. 2001;414:799-806.
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
2
-
-
0030840464
-
STATs and gene regulation
-
Darnell JE Jr. STATs and gene regulation. Science. 1997:277:1630-5.
-
(1997)
Science
, vol.277
, pp. 1630-1635
-
-
Darnell Jr, J.E.1
-
3
-
-
0033828672
-
SOCS: Physiological suppressors of cytokine signaling
-
Krebs DL, Hilton DJ. SOCS: physiological suppressors of cytokine signaling. J Cell Sci. 2000;113:2813-9.
-
(2000)
J Cell Sci
, vol.113
, pp. 2813-2819
-
-
Krebs, D.L.1
Hilton, D.J.2
-
5
-
-
0034458143
-
Stat 5B, activated by insulin in a Jak-independent fashion, plays a role in glucokinase gene transcription
-
Sawka-Verhelle D, Tartare-Deckert S, Decaux JF, Girard J, Van Obberghen E. Stat 5B, activated by insulin in a Jak-independent fashion, plays a role in glucokinase gene transcription. Endocrinology. 2000:141:1977-88.
-
(2000)
Endocrinology
, vol.141
, pp. 1977-1988
-
-
Sawka-Verhelle, D.1
Tartare-Deckert, S.2
Decaux, J.F.3
Girard, J.4
Van Obberghen, E.5
-
6
-
-
0345148324
-
A cellular reporter assay to monitor insulin receptor kinase activity based on STAT 5-dependent luciferase gene expression
-
Storz P, Doppler H, Horn-Muller J, Groner B, Pfizenmaier K, Muller G. A cellular reporter assay to monitor insulin receptor kinase activity based on STAT 5-dependent luciferase gene expression. Anal Biochem. 1999:276:97-104.
-
(1999)
Anal Biochem
, vol.276
, pp. 97-104
-
-
Storz, P.1
Doppler, H.2
Horn-Muller, J.3
Groner, B.4
Pfizenmaier, K.5
Muller, G.6
-
7
-
-
0034717062
-
-
Emanuelli B, Peraldi P, Filloux C, Sawka-Verhelle D, Hilton D, Van Obberghen E. SOCS-3 is an insulin-induced negative regulator of insulin signaling. J Biol Chem. 2000;275:15985-91.
-
Emanuelli B, Peraldi P, Filloux C, Sawka-Verhelle D, Hilton D, Van Obberghen E. SOCS-3 is an insulin-induced negative regulator of insulin signaling. J Biol Chem. 2000;275:15985-91.
-
-
-
-
8
-
-
0035816697
-
Insulin induces suppressor of cytokine signaling-3 tyrosine phosphorylation through janus-activated kinase
-
Peraldi P, Filloux C, Emanuelli B, Hilton DJ, Van Obberghen E. Insulin induces suppressor of cytokine signaling-3 tyrosine phosphorylation through janus-activated kinase. J Biol Chem. 2001;276:24614-20.
-
(2001)
J Biol Chem
, vol.276
, pp. 24614-24620
-
-
Peraldi, P.1
Filloux, C.2
Emanuelli, B.3
Hilton, D.J.4
Van Obberghen, E.5
-
9
-
-
0037853260
-
Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes
-
Senn JJ, Klover PJ, Nowak IA, et al. Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes. J Biol Chem. 2003:278:13740-6.
-
(2003)
J Biol Chem
, vol.278
, pp. 13740-13746
-
-
Senn, J.J.1
Klover, P.J.2
Nowak, I.A.3
-
10
-
-
3142723189
-
Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse
-
Ueki K, Kondo T, Tseng YH, Kahn CR. Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse. Proc Natl Acad Sci USA. 2004:101:10422-7.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10422-10427
-
-
Ueki, K.1
Kondo, T.2
Tseng, Y.H.3
Kahn, C.R.4
-
11
-
-
4544256147
-
Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling
-
Shi H, Tzameli I, Bjorbaek C, Flier JS. Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling. J Biol Chem. 2004;279:34733-40.
-
(2004)
J Biol Chem
, vol.279
, pp. 34733-34740
-
-
Shi, H.1
Tzameli, I.2
Bjorbaek, C.3
Flier, J.S.4
-
12
-
-
33644782904
-
Overexpression of suppressor of cytokine signaling 3 in adipose tissue causes local but not systemic insulin resistance
-
Shi H, Cave B, Inouye K, Bjorbaek C, Flier JS. Overexpression of suppressor of cytokine signaling 3 in adipose tissue causes local but not systemic insulin resistance. Diabetes. 2006;55:699-707.
-
(2006)
Diabetes
, vol.55
, pp. 699-707
-
-
Shi, H.1
Cave, B.2
Inouye, K.3
Bjorbaek, C.4
Flier, J.S.5
-
13
-
-
13444256225
-
Activation of SOCS-3 by resistin
-
Steppan CM, Wang J, Whiteman EL, Birnbaum MJ, Lazar MA. Activation of SOCS-3 by resistin. Mol Cell Biol. 2005;25:1569-75.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 1569-1575
-
-
Steppan, C.M.1
Wang, J.2
Whiteman, E.L.3
Birnbaum, M.J.4
Lazar, M.A.5
-
14
-
-
0035854723
-
Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor: A potential mechanism for cytokine-mediated insulin resistance
-
Mooney RA, Senn J, Cameron S, et al. Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor: a potential mechanism for cytokine-mediated insulin resistance. J Biol Chem. 2001;276:25889-93.
-
(2001)
J Biol Chem
, vol.276
, pp. 25889-25893
-
-
Mooney, R.A.1
Senn, J.2
Cameron, S.3
-
15
-
-
0032577926
-
Highly specific and quantitative activation of STATs in 3T3-L1 adipocytes
-
Balhoff JP, Stephens JM. Highly specific and quantitative activation of STATs in 3T3-L1 adipocytes. Biochem Biophys Res Commun. 1998;247:894-900.
-
(1998)
Biochem Biophys Res Commun
, vol.247
, pp. 894-900
-
-
Balhoff, J.P.1
Stephens, J.M.2
-
16
-
-
0035434522
-
Signaling pathways activated by the growth hormone receptor
-
Herrington J, Carter-Su C. Signaling pathways activated by the growth hormone receptor. Trends Endocrinol Metab. 2001;12:252-7.
-
(2001)
Trends Endocrinol Metab
, vol.12
, pp. 252-257
-
-
Herrington, J.1
Carter-Su, C.2
-
17
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970;227:680-5.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
18
-
-
0025837140
-
Transcriptional repression of the GLUT4 and C/EBP genes in 3T3-L1 adipocytes by tumor necrosis factor-alpha
-
Stephens JM, Pekala PH. Transcriptional repression of the GLUT4 and C/EBP genes in 3T3-L1 adipocytes by tumor necrosis factor-alpha. J Biol Chem. 1991;266:21839-45.
-
(1991)
J Biol Chem
, vol.266
, pp. 21839-21845
-
-
Stephens, J.M.1
Pekala, P.H.2
-
19
-
-
0037428311
-
Growth hormone, but not insulin, activates STAT5 proteins in adipocytes in vitro and in vivo
-
Zvonic S, Story DJ, Stephens JM, Mynatt RL. Growth hormone, but not insulin, activates STAT5 proteins in adipocytes in vitro and in vivo. Biochem Biophys Res Commun. 2003:302:359-62.
-
(2003)
Biochem Biophys Res Commun
, vol.302
, pp. 359-362
-
-
Zvonic, S.1
Story, D.J.2
Stephens, J.M.3
Mynatt, R.L.4
-
20
-
-
12244276721
-
Dual mechanisms of signal transducer and activator of transcription 5 activation by the insulin receptor
-
Le MN, Kohanski RA, Wang LH, Sadowaski HB. Dual mechanisms of signal transducer and activator of transcription 5 activation by the insulin receptor. Mol Endocrinol. 2002:16:2764-79.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 2764-2779
-
-
MN, L.1
Kohanski, R.A.2
Wang, L.H.3
Sadowaski, H.B.4
-
21
-
-
0036830636
-
SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2
-
Rui L, Yuan M, Frantz D, Shoelson S, White MF. SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2. J Biol Chem. 2002:277:42394-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 42394-42398
-
-
Rui, L.1
Yuan, M.2
Frantz, D.3
Shoelson, S.4
White, M.F.5
-
22
-
-
33646041304
-
Induction of SOCS-3 is insufficient to confer IRS-1 protein degradation in 3T3-L1 adipocytes
-
He F, Stephens JM. Induction of SOCS-3 is insufficient to confer IRS-1 protein degradation in 3T3-L1 adipocytes. Biochem Biophys Res Commun. 2006;344:95-8.
-
(2006)
Biochem Biophys Res Commun
, vol.344
, pp. 95-98
-
-
He, F.1
Stephens, J.M.2
-
23
-
-
0034792866
-
Neutralization of interferon-gamma in neonatal SOCS1 -/- mice prevents fatty degeneration of the liver but not subsequent fatal inflammatory disease
-
Bullen DV, Darwiche R, Metcalf D, Handman E, Alexander WS. Neutralization of interferon-gamma in neonatal SOCS1 -/- mice prevents fatty degeneration of the liver but not subsequent fatal inflammatory disease. Immunology. 2001:104:92-81.
-
(2001)
Immunology
, vol.104
, pp. 92-81
-
-
Bullen, D.V.1
Darwiche, R.2
Metcalf, D.3
Handman, E.4
Alexander, W.S.5
-
24
-
-
0035280536
-
Lack of Socs2 expression causes the high-growth phenotype in mice
-
Horvat S, Medrano JF. Lack of Socs2 expression causes the high-growth phenotype in mice. Genomics. 2001:72:209-12.
-
(2001)
Genomics
, vol.72
, pp. 209-212
-
-
Horvat, S.1
Medrano, J.F.2
-
25
-
-
0033520389
-
SOCS3 is essential in the regulation of fetal liver erythropoiesis
-
Marine JC, McKay C, Wang D, et al. SOCS3 is essential in the regulation of fetal liver erythropoiesis. Cell. 1999:98:617-27.
-
(1999)
Cell
, vol.98
, pp. 617-627
-
-
Marine, J.C.1
McKay, C.2
Wang, D.3
-
26
-
-
0035979275
-
Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3
-
Roberts AW, Robb L, Rakar S, et al. Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3. Proc Natl Acad Sci USA. 2001:98:9324-9.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9324-9329
-
-
Roberts, A.W.1
Robb, L.2
Rakar, S.3
-
27
-
-
0019970112
-
Effects of growth hormone on insulin action in man: Mechanisms of insulin resistance, impaired suppression of glucose production, and impaired stimulation of glucose utilization
-
Rizza RA, Mandarine LJ, Gerich JE. Effects of growth hormone on insulin action in man: mechanisms of insulin resistance, impaired suppression of glucose production, and impaired stimulation of glucose utilization. Diabetes. 1982;31:663-69.
-
(1982)
Diabetes
, vol.31
, pp. 663-669
-
-
Rizza, R.A.1
Mandarine, L.J.2
Gerich, J.E.3
-
28
-
-
0022591467
-
The role of autoregulation of the hepatic glucose production in man: Response to a physiologic decrement in plasma glucose
-
Hansen I, Firth R, Raymond M, Cryer P, Rizza R. The role of autoregulation of the hepatic glucose production in man: response to a physiologic decrement in plasma glucose. Diabetes. 1986;35:186-91.
-
(1986)
Diabetes
, vol.35
, pp. 186-191
-
-
Hansen, I.1
Firth, R.2
Raymond, M.3
Cryer, P.4
Rizza, R.5
-
29
-
-
0030740995
-
Growth hormone-induced insulin resistance: Role of the insulin receptor, IRS-1, GLUT-1, and GLUT-4. Am
-
Smith TR, Elmendorf JS, David TS, Turinsky J. Growth hormone-induced insulin resistance: role of the insulin receptor, IRS-1, GLUT-1, and GLUT-4. Am J Physiol. 1997;272:E1071-9.
-
(1997)
J Physiol
, vol.272
-
-
Smith, T.R.1
Elmendorf, J.S.2
David, T.S.3
Turinsky, J.4
-
30
-
-
0030757093
-
Effect of chronic growth hormone treatment on insulin signal transduction in rat tissues
-
Thirone AC, Carvalho CR, Brenelli SL, Velloso LA, Saad MJ. Effect of chronic growth hormone treatment on insulin signal transduction in rat tissues. Mol Cell Endocrinol. 1997;130:33-42.
-
(1997)
Mol Cell Endocrinol
, vol.130
, pp. 33-42
-
-
Thirone, A.C.1
Carvalho, C.R.2
Brenelli, S.L.3
Velloso, L.A.4
Saad, M.J.5
-
31
-
-
0036521760
-
Growth hormone-induced alterations in the insulin-signaling system
-
Dominici FP, Turyn D. Growth hormone-induced alterations in the insulin-signaling system. Exp Biol Med (Maywood). 2002;227:149-57.
-
(2002)
Exp Biol Med (Maywood)
, vol.227
, pp. 149-157
-
-
Dominici, F.P.1
Turyn, D.2
-
32
-
-
0034864712
-
The ubiquitin-proteasomepathway regulates lysosomal degradation of the growth hormone receptor and its ligand
-
van Kerkhof P, Strous GJ. The ubiquitin-proteasomepathway regulates lysosomal degradation of the growth hormone receptor and its ligand. Biochem Soc Trans. 2001;29:488-93.
-
(2001)
Biochem Soc Trans
, vol.29
, pp. 488-493
-
-
van Kerkhof, P.1
Strous, G.J.2
-
33
-
-
0035980108
-
Growth hormone receptor ubiquitination, endocytosis, and degradation are independent of signal transduction via Janus kinase 2
-
Alves dos Santos CM, ten Broeke T, Strous GJ. Growth hormone receptor ubiquitination, endocytosis, and degradation are independent of signal transduction via Janus kinase 2. J Biol Chem. 2001;276:32635-41.
-
(2001)
J Biol Chem
, vol.276
, pp. 32635-32641
-
-
Alves dos Santos, C.M.1
ten Broeke, T.2
Strous, G.J.3
-
34
-
-
4344698092
-
Suppressor of cytokine signaling 3 expression and insulin resistance in skeletal muscle of obese and type 2 diabetic patients
-
Rieusset J, Bouzakri K, Chevillotte E, et al. Suppressor of cytokine signaling 3 expression and insulin resistance in skeletal muscle of obese and type 2 diabetic patients. Diabetes. 2004:53:2232-41.
-
(2004)
Diabetes
, vol.53
, pp. 2232-2241
-
-
Rieusset, J.1
Bouzakri, K.2
Chevillotte, E.3
-
35
-
-
31844441456
-
Common polymorphisms in SOCS-3 are not associated with body weight, insulin sensitivity or lipid profile in normal female twins
-
Jamshidi Y, Snieder H, Wang X, Spector TD, Carter ND, O'Dell SD. Common polymorphisms in SOCS-3 are not associated with body weight, insulin sensitivity or lipid profile in normal female twins. Diabetologia. 2006;49:306-10.
-
(2006)
Diabetologia
, vol.49
, pp. 306-310
-
-
Jamshidi, Y.1
Snieder, H.2
Wang, X.3
Spector, T.D.4
Carter, N.D.5
O'Dell, S.D.6
|