-
1
-
-
0030615201
-
Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
-
Barnes, P.J., and Karin, M. 1997. Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 336:1066-1071.
-
(1997)
N. Engl. J. Med.
, vol.336
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
2
-
-
0036234459
-
Missing pieces in the NF-kB puzzle
-
Ghosh, S., and Karin, M. 2002. Missing pieces in the NF-kB puzzle. Cell. 109(Suppl.):S81-S96.
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
Ghosh, S.1
Karin, M.2
-
3
-
-
0033607313
-
The NF-kB activation pathway: A paradigm in information transfer from membrane to nucleus
-
Rothwarf, D.M., and Karin, M. 1999. The NF-kB activation pathway: a paradigm in information transfer from membrane to nucleus. Sci. STKE. 1999:RE1.
-
(1999)
Sci. STKE
, vol.1999
-
-
Rothwarf, D.M.1
Karin, M.2
-
4
-
-
0036781052
-
NF-kB regulation in the immune system
-
Li, Q., and Verma, I.M. 2002. NF-kB regulation in the immune system. Nat. Rev. Immunol. 2:725-734.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 725-734
-
-
Li, Q.1
Verma, I.M.2
-
5
-
-
0038587747
-
The two faces of IKK and NF-kB inhibition: Prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion
-
Chen, L.W., et al. 2003. The two faces of IKK and NF-kB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion. Nat. Med. 9:575-581.
-
(2003)
Nat. Med.
, vol.9
, pp. 575-581
-
-
Chen, L.W.1
-
6
-
-
4043088499
-
IKKb links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
Greten, F.R., et al. 2004. IKKb links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell. 118:285-296.
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
-
7
-
-
20044387026
-
IKKb links inflammation to obesity-induced insulin resistance
-
Arkan, M.C., et al. 2005. IKKb links inflammation to obesity-induced insulin resistance. Nat. Med. 11:191-198.
-
(2005)
Nat. Med.
, vol.11
, pp. 191-198
-
-
Arkan, M.C.1
-
8
-
-
33750595325
-
Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass promotes regeneration
-
doi:10.1172/JCI28721
-
Mourkioti, F., et al. 2006. Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration. J. Clin. Invest. 116:2945-2954. doi:10.1172/JCI28721.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2945-2954
-
-
Mourkioti, F.1
-
9
-
-
16644402070
-
Duchenne muscular dystrophy and dystrophin: Pathogenesis and opportunities for treatment
-
Nowak, K.J., and Davies, K.E. 2004. Duchenne muscular dystrophy and dystrophin: pathogenesis and opportunities for treatment. EMBO Rep. 5:872-876.
-
(2004)
EMBO Rep.
, vol.5
, pp. 872-876
-
-
Nowak, K.J.1
Davies, K.E.2
-
10
-
-
0036830917
-
Cachexia in cancer patients
-
Tisdale, M.J. 2002. Cachexia in cancer patients. Nat. Rev. Cancer. 2:862-871.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 862-871
-
-
Tisdale, M.J.1
-
11
-
-
6944247647
-
Inflammatory disorders of muscle: Progress in polymyositis, dermatomyositis and inclusion body myositis
-
Dalakas, M.C. 2004. Inflammatory disorders of muscle: progress in polymyositis, dermatomyositis and inclusion body myositis. Curr. Opin. Neurol. 17:561-567.
-
(2004)
Curr. Opin. Neurol.
, vol.17
, pp. 561-567
-
-
Dalakas, M.C.1
-
12
-
-
5444262078
-
IKKb/NF-kB activation causes severe muscle wasting in mice
-
Cai, D., et al. 2004. IKKb/NF-kB activation causes severe muscle wasting in mice. Cell. 119:285-298.
-
(2004)
Cell
, vol.119
, pp. 285-298
-
-
Cai, D.1
-
13
-
-
0035136062
-
Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle
-
Musaro, A., et al. 2001. Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle. Nat. Genet. 27:195-200.
-
(2001)
Nat. Genet.
, vol.27
, pp. 195-200
-
-
Musaro, A.1
-
14
-
-
0035941020
-
Identification of ubiquitin ligases required for skeletal muscle atrophy
-
Bodine, S.C., et al. 2001. Identification of ubiquitin ligases required for skeletal muscle atrophy. Science. 294:1704-1708.
-
(2001)
Science
, vol.294
, pp. 1704-1708
-
-
Bodine, S.C.1
-
15
-
-
2042425906
-
The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors
-
Stitt, T.N., et al. 2004. The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol. Cell. 14:395-403.
-
(2004)
Mol. Cell.
, vol.14
, pp. 395-403
-
-
Stitt, T.N.1
-
16
-
-
11144356337
-
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
-
Sandri, M., et al. 2004. Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell. 117:399-412.
-
(2004)
Cell
, vol.117
, pp. 399-412
-
-
Sandri, M.1
-
17
-
-
0036009115
-
NF-kB at the crossroads of life and death
-
Karin, M., and Lin, A. 2002. NF-kB at the crossroads of life and death. Nat. Immunol. 3:221-227.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
18
-
-
32044447161
-
The E3 ubiquitin ligase itch couples JNK activation to TNFa-induced cell death by inducing c-FLIP(L) turnover
-
Chang, L., et al. 2006. The E3 ubiquitin ligase itch couples JNK activation to TNFa-induced cell death by inducing c-FLIP(L) turnover. Cell. 124:601-613.
-
(2006)
Cell
, vol.124
, pp. 601-613
-
-
Chang, L.1
-
19
-
-
0029992609
-
Suppression of TNFa-induced apoptosis by NF-kB
-
Van Antwerp, D.J., Martin, S.J., Kafri, T., Green, D.R., and Verma, I.M. 1996. Suppression of TNFa-induced apoptosis by NF-kB. Science. 274:787-789.
-
(1996)
Science
, vol.274
, pp. 787-789
-
-
Van Antwerp, D.J.1
Martin, S.J.2
Kafri, T.3
Green, D.R.4
Verma, I.M.5
-
20
-
-
14844327760
-
Reactive oxygen species promote TNFa-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
-
Kamata, H., et al. 2005. Reactive oxygen species promote TNFa-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell. 120:649-661.
-
(2005)
Cell
, vol.120
, pp. 649-661
-
-
Kamata, H.1
-
21
-
-
2342464085
-
The two NF-kB activation pathways and their role in innate and adaptive immunity
-
Bonizzi, G., and Karin, M. 2004. The two NF-kB activation pathways and their role in innate and adaptive immunity. Trends Immunol. 25:280-288.
-
(2004)
Trends Immunol.
, vol.25
, pp. 280-288
-
-
Bonizzi, G.1
Karin, M.2
-
22
-
-
0346505340
-
The IKK NF-kB system: A treasure trove for drug development
-
Karin, M., Yamamoto, Y., and Wang, Q.M. 2004. The IKK NF-kB system: a treasure trove for drug development. Nat. Rev. Drug Discov. 3:17-26.
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 17-26
-
-
Karin, M.1
Yamamoto, Y.2
Wang, Q.M.3
-
23
-
-
0037449711
-
BMS-345541 is a highly selective inhibitor of IkB kinase that binds at an allosteric site of the enzyme and blocks NF-kB-dependent transcription in mice
-
Burke, J.R., et al. 2003. BMS-345541 is a highly selective inhibitor of IkB kinase that binds at an allosteric site of the enzyme and blocks NF-kB-dependent transcription in mice. J. Biol. Chem. 278:1450-1456.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1450-1456
-
-
Burke, J.R.1
-
24
-
-
10644270096
-
Sensitization of tumor cells toward chemotherapy: Enhancing the efficacy of camptothecin with imidazolines
-
Sharma, V., Lansdell, T.A., Peddibhotla, S., and Tepe, J.J. 2004. Sensitization of tumor cells toward chemotherapy: enhancing the efficacy of camptothecin with imidazolines. Chem. Biol. 11:1689-1699.
-
(2004)
Chem. Biol.
, vol.11
, pp. 1689-1699
-
-
Sharma, V.1
Lansdell, T.A.2
Peddibhotla, S.3
Tepe, J.J.4
|