Emergence of a novel lamivudine-resistant hepatitis B virus variant with a substitution outside the YMDD motif

Antimicrobial Agents and Chemotherapy

Volumn 50, Issue 11, 2006, Pages 3867-3874

  Yatsuji, Hiromi ^a,b   Noguchi, Chiemi ^a,b   Hiraga, Nobuhiko ^a,b   Mori, Nami ^a,b   Tsuge, Masataka ^a,b   Imamura, Michio ^a,b   Takahashi, Shoichi ^a,b   Iwao, Eiji ^c   Fujimoto, Yoshifumi ^b,d   Ochi, Hidenori ^b,d   Abe, Hiromi ^a,d   Maekawa, Toshiro ^d   Tateno, Chise ^b,e   Yoshizato, Katsutoshi ^b,e   Suzuki, Fumitaka ^f   Kumada, Hiromitsu ^f   Chayama, Kazuaki ^a,b,d  

^a HIROSHIMA UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^d INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^e Hiroshima Prefectural Institute of Industrial Science and Technology   (Japan)

^f TORANOMON HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADEFOVIR; CYSTEINE; ENTECAVIR; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VIRUS POLYMERASE; LAMIVUDINE; LEUCINE; PEPTIDE NUCLEIC ACID; RNA DIRECTED DNA POLYMERASE; SERINE; TRYPTOPHAN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHIMERA; CONTROLLED STUDY; DRUG SENSITIVITY; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; LONG TERM CARE; MOUSE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SENSITIVITY AND SPECIFICITY; STOP CODON; TYROSINYLMETHIONYLASPARTYLASPARTATE MOTIF; VIRUS DETECTION; VIRUS MUTATION; VIRUS STRAIN;

ADENINE; AMINO ACID MOTIFS; ANIMALS; ANTIVIRAL AGENTS; BLOTTING, SOUTHERN; CLONING, MOLECULAR; DNA, VIRAL; DRUG RESISTANCE, VIRAL; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HEPATOCYTES; HUMANS; LAMIVUDINE; MICE; MUTATION; PHOSPHONIC ACIDS; PLASMIDS; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RNA, VIRAL; TRANSFECTION; VIRUS REPLICATION;

EID: 33750588091     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00239-06     Document Type: Article

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