Histological changes in liver biopsies after one year of lamivudine treatment in patients with chronic hepatitis B infection

Journal of Hepatology

Volumn 30, Issue 5, 1999, Pages 743-748

  Suzuki, Yoshiyuki ^d   Kumada, Hiromitsu ^d   Ikeda, Kenji ^d   Chayama, Kazuaki ^d   Arase, Yasuji ^d   Saitoh, Satoshi ^d   Tsubota, Akihito ^d   Kobayashi, Masahiro ^d   Koike, Morio ^a   Ogawa, Nobuya ^b   Tanikawa, Kyuichi ^c  

^a TOKYO METROPOLITAN KOMAGOME HOSPITAL   (Japan)

^b EHIME UNIVERSITY   (Japan)

^c KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d NONE

Author keywords

Chronic hepatitis B; HAI score; Lamivudine

Indexed keywords

HEPATITIS B(E) ANTIGEN; LAMIVUDINE;

ARTICLE; CHRONIC HEPATITIS; CLINICAL ARTICLE; DRUG EFFECT; DRUG EFFICACY; HEPATITIS B; HEPATITIS B VIRUS; HISTOPATHOLOGY; HUMAN; LIVER BIOPSY; LIVER HISTOLOGY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; TREATMENT OUTCOME;

EID: 0033067028     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(99)80123-8     Document Type: Article

References (7)

1. Coates JAV, Cammack N, Jenkinson HJ, Jowett AJ, Jowett MI, Pearson BA, et al. (-)-2′-deoxy-3′-thiacytidine is a potent highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vivo. Antimicrob Agents Chemother. 35:1992;733-739.
2. Nowak MA, Bonhoeffer S, Hill AM, Boehme R, Thomas HC, McDade H. Viral dynamics in hepatitis B virus infection. Proc Natl Acad Sci USA. 93:1996;4398-4402.
3. Dienstag JL, Perrillo RP, Schiff ER, Bartholomew M, Vicary C, Rubin M. A preliminary trial of lamivudine for chronic hepatitis B infection. N Engl J Med. 333:1995;1657-1661.
4. Lai CL, Liaw YF, Leung NWY, Chang TT, Guan R, Tai DI, et al. A one year trial of lamivudine for chronic hepatitis B. N Engl J Med. 339:1998;61-68.
5. Honkoop P, de Man RA, Zondervan PE, Schalm SW. Histological improvement in patients with chronic hepatitis B virus infection treated with lamivudine. Liver. 17:1997;103-106.
6. Tanikawa K, Ichida F, Suzuki H, Hayashi N, Omata M, Kumada H, et al. Studies on the optimum dose and usefulness of GG714 (lamivudine) in chronic hepatitis B patients. Kan Tan Sui. 33:1997;529-547.
7. Knodell RG, Ishak KG, Black WC, Chen TS, Craig R, Kaplowitz N, et al. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology. 1:1981;431-435.