메뉴 건너뛰기




Volumn 36, Issue 6, 2003, Pages 687-696

Prevalence and clinical correlates of YMDD variants during lamivudine therapy for patients with chronic hepatitis B

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ASPARTIC ACID; LAMIVUDINE; METHIONINE; PLACEBO; TYROSINE; VIRUS DNA;

EID: 0037443950     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/368083     Document Type: Article
Times cited : (573)

References (44)
  • 1
    • 0033976871 scopus 로고    scopus 로고
    • Long-term mutation rates in the hepatitis B virus genome
    • Hannoun C, Horal P, Lindh M. Long-term mutation rates in the hepatitis B virus genome. J Gen Virol 2000; 81:75-83.
    • (2000) J Gen Virol , vol.81 , pp. 75-83
    • Hannoun, C.1    Horal, P.2    Lindh, M.3
  • 2
    • 0029931919 scopus 로고    scopus 로고
    • Antiviral resistance: Mechanisms, clinical significance, and future implications
    • Kimberlin DYV, Whitley RJ. Antiviral resistance: mechanisms, clinical significance, and future implications. J Antimicrob Chemother 1996; 37:403-21.
    • (1996) J Antimicrob Chemother , vol.37 , pp. 403-421
    • Kimberlin, D.W.1    Whitley, R.J.2
  • 3
    • 0027374758 scopus 로고
    • A short-term clinical evaluation of L-697,661, a non-nucleoside inhibitor of HIV-1 reverse transcriptase
    • Saag MS, Emini EA, Laskin OL, et al. A short-term clinical evaluation of L-697,661, a non-nucleoside inhibitor of HIV-1 reverse transcriptase. N Engl J Med 1993; 329:1065-72.
    • (1993) N Engl J Med , vol.329 , pp. 1065-1072
    • Saag, M.S.1    Emini, E.A.2    Laskin, O.L.3
  • 4
    • 0026077654 scopus 로고
    • Ganciclovir-resistant cytomegalovirus clinical isolates: Mode of resistance to ganciclovir
    • Stanat SC, Reardon JE, Erice A, et al. Ganciclovir-resistant cytomegalovirus clinical isolates: mode of resistance to ganciclovir. Antimicrob Agents Chemother 1991; 35:2191-7.
    • (1991) Antimicrob Agents Chemother , vol.35 , pp. 2191-2197
    • Stanat, S.C.1    Reardon, J.E.2    Erice, A.3
  • 5
    • 0026782503 scopus 로고
    • A ganciclovir-resistant clinical isolate of human cytomegalovirus exhibiting cross-resistance to other DNA polymerase inhibitors
    • Tatarowicz WA, Lurain NS, Thompson KD. A ganciclovir-resistant clinical isolate of human cytomegalovirus exhibiting cross-resistance to other DNA polymerase inhibitors. J Infect Dis 1992; 166:904-7.
    • (1992) J Infect Dis , vol.166 , pp. 904-907
    • Tatarowicz, W.A.1    Lurain, N.S.2    Thompson, K.D.3
  • 6
    • 0020073621 scopus 로고
    • Isolation and characterization of resistant herpes simplex virus after acyclovir therapy
    • Burns WH, Santos GW, Saral R, et al. Isolation and characterization of resistant herpes simplex virus after acyclovir therapy. Lancet 1982; 1(8269) 421-3.
    • (1982) Lancet , vol.1 , Issue.8269 , pp. 421-423
    • Burns, W.H.1    Santos, G.W.2    Saral, R.3
  • 7
    • 0032499913 scopus 로고    scopus 로고
    • A one-year trial of lamivudine for chronic hepatitis B
    • Lai CL, Chien RN, Leung NWY, et al. A one-year trial of lamivudine for chronic hepatitis B. N Engl J Med 1998; 339:61-8.
    • (1998) N Engl J Med , vol.339 , pp. 61-68
    • Lai, C.L.1    Chien, R.N.2    Leung, N.W.Y.3
  • 9
    • 0032751727 scopus 로고    scopus 로고
    • Quantitation of hepatitis B viremia and emergence of YMDD variants in patients with chronic hepatitis B treated with lamivudine
    • Gauthier J, Bourne EJ, Lutz MYV, et al. Quantitation of hepatitis B viremia and emergence of YMDD variants in patients with chronic hepatitis B treated with lamivudine. J Infect Dis 1999; 180:1757-62.
    • (1999) J Infect Dis , vol.180 , pp. 1757-1762
    • Gauthier, J.1    Bourne, E.J.2    Lutz, M.Y.V.3
  • 10
    • 0141643931 scopus 로고    scopus 로고
    • Pathogenesis of hepadnavirus infections
    • Lai CL, Locarnini S, eds. London: International Medical Press
    • Mason W, Litwin S. Pathogenesis of hepadnavirus infections. In: Lai CL, Locarnini S, eds. A guide to hepatitis B virus. London: International Medical Press, 2003:99-113.
    • (2003) A Guide to Hepatitis B Virus , pp. 99-113
    • Mason, W.1    Litwin, S.2
  • 11
    • 0032701683 scopus 로고    scopus 로고
    • Therapy of chronic hepatitis B virus infection: Inhibition of the viral polymerase and other antiviral strategies
    • Zoulim F. Therapy of chronic hepatitis B virus infection: inhibition of the viral polymerase and other antiviral strategies. Antiviral Res 1999; 44:1-30.
    • (1999) Antiviral Res , vol.44 , pp. 1-30
    • Zoulim, F.1
  • 12
    • 0342378081 scopus 로고    scopus 로고
    • Naturally occurring hepatitis B virus genomes bearing the hallmarks of retroviral G to A hypermuration
    • Gunther S, Sommer G, Plikat U, et al. Naturally occurring hepatitis B virus genomes bearing the hallmarks of retroviral G to A hypermuration. Virology 1997; 235:104-8.
    • (1997) Virology , vol.235 , pp. 104-108
    • Gunther, S.1    Sommer, G.2    Plikat, U.3
  • 13
    • 0028799649 scopus 로고
    • Variants of hepatitis B, C, and D viruses: Molecular biology and clinical signifcance
    • Blum HE. Variants of hepatitis B, C, and D viruses: molecular biology and clinical signifcance. Digestion 1995; 56:85-95.
    • (1995) Digestion , vol.56 , pp. 85-95
    • Blum, H.E.1
  • 14
    • 0031037065 scopus 로고    scopus 로고
    • Hepatitis-B-virus resistance to lamivudine given for recurrent infection after orthotopic liver transplantation
    • Bartholomew MM, Jansen RW, Jeffers LJ, et al. Hepatitis-B-virus resistance to lamivudine given for recurrent infection after orthotopic liver transplantation. Lancet 1997; 349:20-2.
    • (1997) Lancet , vol.349 , pp. 20-22
    • Bartholomew, M.M.1    Jansen, R.W.2    Jeffers, L.J.3
  • 15
    • 0031780935 scopus 로고    scopus 로고
    • Identification and characterization of mutations in hepatitis B virus resistant to lamivudine
    • Allen MI, Deslauriers M, Andrews CW, et al. Identification and characterization of mutations in hepatitis B virus resistant to lamivudine. Hepatology 1998; 27:1670-7.
    • (1998) Hepatology , vol.27 , pp. 1670-1677
    • Allen, M.I.1    Deslauriers, M.2    Andrews, C.W.3
  • 16
    • 0033031769 scopus 로고    scopus 로고
    • Functional analysis of mutations conferring lamivudine resistance on hepatitis B virus
    • Ling R, Harrison TJ. Functional analysis of mutations conferring lamivudine resistance on hepatitis B virus. J Gen Virol 1999; 80:601-6.
    • (1999) J Gen Virol , vol.80 , pp. 601-606
    • Ling, R.1    Harrison, T.J.2
  • 17
    • 0031938029 scopus 로고    scopus 로고
    • Hepatitis B mutants induced by 3TC and famciclovir are replication defective
    • Melegari M, Scaglioni PP, Wands JR. Hepatitis B mutants induced by 3TC and famciclovir are replication defective. Hepatology 1998; 27:628-33.
    • (1998) Hepatology , vol.27 , pp. 628-633
    • Melegari, M.1    Scaglioni, P.P.2    Wands, J.R.3
  • 18
    • 17344373482 scopus 로고    scopus 로고
    • Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy
    • Chayama K, Suzuki Y, Kobayashi M, et al. Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy. Hepatology 1998; 27:1711-6.
    • (1998) Hepatology , vol.27 , pp. 1711-1716
    • Chayama, K.1    Suzuki, Y.2    Kobayashi, M.3
  • 19
    • 0032751727 scopus 로고    scopus 로고
    • Quantitation of hepatitis B viremia and emergence of YMDD variants in patients with chronic hepatitis B treated with lamivudine
    • Gauthier J, Bourne EJ, Lutz MW, et al. Quantitation of hepatitis B viremia and emergence of YMDD variants in patients with chronic hepatitis B treated with lamivudine. J Infect Dis 1999; 180:1757-62.
    • (1999) J Infect Dis , vol.180 , pp. 1757-1762
    • Gauthier, J.1    Bourne, E.J.2    Lutz, M.W.3
  • 20
    • 0033592764 scopus 로고    scopus 로고
    • Lamivudine as initial treatment for chronic hepatitis B in the United States
    • Dienstag JL, SchiffER, Wright TL, et al. Lamivudine as initial treatment for chronic hepatitis B in the United States. N Engl J Med 1999; 341: 1256-63.
    • (1999) N Engl J Med , vol.341 , pp. 1256-1263
    • Dienstag, J.L.1    Schiffer, E.R.2    Wright, T.L.3
  • 21
    • 0034105307 scopus 로고    scopus 로고
    • Lamivudine and alpha interferon combination treatment of patients with chronic hepatitis B infection: A randomized trial
    • Schalm SW, Heathcote J, Cianciara J, et al. Lamivudine and alpha interferon combination treatment of patients with chronic hepatitis B infection: a randomized trial. Gut 2000; 46:562-8.
    • (2000) Gut , vol.46 , pp. 562-568
    • Schalm, S.W.1    Heathcote, J.2    Cianciara, J.3
  • 22
    • 0001279724 scopus 로고    scopus 로고
    • A placebo controlled study of lamivudine and interferon alpha-2b in patients with chronic hepatitis B who previously failed interferon therapy
    • abstract 901
    • Schiff E, Karayalcin S, Grimm I, et al. A placebo controlled study of lamivudine and interferon alpha-2b in patients with chronic hepatitis B who previously failed interferon therapy [abstract 901]. Hepatology 1998; 28:388A.
    • (1998) Hepatology , vol.28
    • Schiff, E.1    Karayalcin, S.2    Grimm, I.3
  • 23
    • 0034235528 scopus 로고    scopus 로고
    • Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B
    • Liaw YF, Leung NWY, Chang TT, et al. Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B. Gastroenterology 2000; 119:172-80.
    • (2000) Gastroenterology , vol.119 , pp. 172-180
    • Liaw, Y.F.1    Leung, N.W.Y.2    Chang, T.T.3
  • 24
    • 0034993211 scopus 로고    scopus 로고
    • Extended lamivudine treatment in patients with chronic hepatitis B enhances hepatitis B e antigen seroconversion rates: Results after three years of therapy
    • Leung N, Lai CL, Chang TT, et al. Extended lamivudine treatment in patients with chronic hepatitis B enhances hepatitis B e antigen seroconversion rates: results after three years of therapy. Hepatology 2001; 33:1527-32.
    • (2001) Hepatology , vol.33 , pp. 1527-1532
    • Leung, N.1    Lai, C.L.2    Chang, T.T.3
  • 25
    • 0032849751 scopus 로고    scopus 로고
    • Two sensitive PCR-based methods for detection of hepatitis B virus variants associated with reduced susceptibility to lamivudine
    • Allen MI, Gauthier J, DesLauriers M, et al. Two sensitive PCR-based methods for detection of hepatitis B virus variants associated with reduced susceptibility to lamivudine. J Clin Microbiol 1999; 37:3338-47.
    • (1999) J Clin Microbiol , vol.37 , pp. 3338-3347
    • Allen, M.I.1    Gauthier, J.2    DesLauriers, M.3
  • 26
    • 0033839986 scopus 로고    scopus 로고
    • Acute exacerbation of chronic hepatitis B virus infection after withdrawal of lamivudine therapy
    • Honkoop P, de Man RA, Niesters HGM, et al. Acute exacerbation of chronic hepatitis B virus infection after withdrawal of lamivudine therapy. Hepatology 2000; 32:635-9.
    • (2000) Hepatology , vol.32 , pp. 635-639
    • Honkoop, P.1    De Man, R.A.2    Niesters, H.G.M.3
  • 27
    • 0029024089 scopus 로고
    • Rapid changes in human immunodeficiency virus type 1 RNA load and appearance of drug-resistant virus populations in persons treated with lamivudine (3TC)
    • Schuurman R, Nijhuis M, van Leeuwen R, et al. Rapid changes in human immunodeficiency virus type 1 RNA load and appearance of drug-resistant virus populations in persons treated with lamivudine (3TC). J Infect Dis 1995; 171:1411-9.
    • (1995) J Infect Dis , vol.171 , pp. 1411-1419
    • Schuurman, R.1    Nijhuis, M.2    Van Leeuwen, R.3
  • 28
    • 0032899269 scopus 로고    scopus 로고
    • Multicenter study of lamivudine therapy for hepatitis B after liver transplantation
    • Perrillo RP, Rakela J, Dienstag JL, et al. Multicenter study of lamivudine therapy for hepatitis B after liver transplantation. Hepatology 1999; 29:1581-6.
    • (1999) Hepatology , vol.29 , pp. 1581-1586
    • Perrillo, R.P.1    Rakela, J.2    Dienstag, J.L.3
  • 29
    • 0000160890 scopus 로고    scopus 로고
    • Improvements in liver histology and cirrhosis with extended lamivudine therapy
    • abstract 546
    • Schiff ER, Heathcote J, Dienstag JL, et al. Improvements in liver histology and cirrhosis with extended lamivudine therapy [abstract 546]. Hepatology 2000; 32:296A.
    • (2000) Hepatology , vol.32
    • Schiff, E.R.1    Heathcote, J.2    Dienstag, J.L.3
  • 30
    • 0001201009 scopus 로고    scopus 로고
    • Liaw YE The effect of longer duration of harbouring lamivudine-resistant hepatitis B virus (YMDD mutants) on liver histology during 3 years lamivudine in Chinese patients
    • abstract 706
    • Leung NW, Lai CL, Guan R, Liaw YE The effect of longer duration of harbouring lamivudine-resistant hepatitis B virus (YMDD mutants) on liver histology during 3 years lamivudine in Chinese patients [abstract 706]. Hepatology 2001; 34:348A.
    • (2001) Hepatology , vol.34
    • Leung, N.W.1    Lai, C.L.2    Guan, R.3
  • 31
    • 0036161381 scopus 로고    scopus 로고
    • Selection of hepatitis B virus polymerase mutants with enhanced replication by lamivudine treatment after liver transplantation
    • Bock C-T, Tillmann HL, Torresi J, et al. Selection of hepatitis B virus polymerase mutants with enhanced replication by lamivudine treatment after liver transplantation. Gastroenterology 2002; 122:264-73.
    • (2002) Gastroenterology , vol.122 , pp. 264-273
    • Bock, C.-T.1    Tillmann, H.L.2    Torresi, J.3
  • 32
    • 0032835661 scopus 로고    scopus 로고
    • Extended lamivudine retreatment for chronic hepatitis B: Maintenance of viral suppression after discontinuation of therapy
    • Dienstag JL, Schiff ER, Mitchell M, et al. Extended lamivudine retreatment for chronic hepatitis B: maintenance of viral suppression after discontinuation of therapy. Hepatology 1999; 30:1082-7.
    • (1999) Hepatology , vol.30 , pp. 1082-1087
    • Dienstag, J.L.1    Schiff, E.R.2    Mitchell, M.3
  • 33
    • 0032783679 scopus 로고    scopus 로고
    • Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy
    • Liaw YF, Chien RN, Yeh CT, et al. Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy. Hepatology 1999; 30:567-72.
    • (1999) Hepatology , vol.30 , pp. 567-572
    • Liaw, Y.F.1    Chien, R.N.2    Yeh, C.T.3
  • 34
    • 0035871869 scopus 로고    scopus 로고
    • Quantitative hepatitis B virus DNA testing for the early prediction of the maintenance of response during lamivudine therapy in patients with chronic hepatitis B
    • Buti M, Sánchez F, Cotrina M, et al. Quantitative hepatitis B virus DNA testing for the early prediction of the maintenance of response during lamivudine therapy in patients with chronic hepatitis B. J Infect Dis 2001; 183:1277-80.
    • (2001) J Infect Dis , vol.183 , pp. 1277-1280
    • Buti, M.1    Sánchez, F.2    Cotrina, M.3
  • 35
    • 0034802516 scopus 로고    scopus 로고
    • Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy
    • Yuen M-F, Sablon E, Hui C-K, Yuan H-J, Decraemer H, Lai C-L. Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy. Hepatology 2001; 34:785-91.
    • (2001) Hepatology , vol.34 , pp. 785-791
    • Yuen, M.-F.1    Sablon, E.2    Hui, C.-K.3    Yuan, H.-J.4    Decraemer, H.5    Lai, C.-L.6
  • 36
    • 17744375593 scopus 로고    scopus 로고
    • Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region
    • Stuyver L, Locarnini S, Lok A, et al. Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region. Hepatology 2001; 33:751-7.
    • (2001) Hepatology , vol.33 , pp. 751-757
    • Stuyver, L.1    Locarnini, S.2    Lok, A.3
  • 37
    • 0035942013 scopus 로고    scopus 로고
    • 20-Fold increase in risk of lamivudine resistance in hepatitis B virus subtype adw
    • Zöllner B, Peterson J, Schröter M, et al. 20-Fold increase in risk of lamivudine resistance in hepatitis B virus subtype adw. Lancet 2001; 357:934-5.
    • (2001) Lancet , vol.357 , pp. 934-935
    • Zöllner, B.1    Peterson, J.2    Schröter, M.3
  • 38
    • 0012401506 scopus 로고    scopus 로고
    • Three years of lamivudine in anti-HBe positive patients decreased virological and biochemical response
    • abstract 358
    • Ruiz L, Valdez A, Cotrina M, et al. Three years of lamivudine in anti-HBe positive patients decreased virological and biochemical response [abstract 358]. J Hepatology 2002; 36(Suppl 1):101.
    • (2002) J Hepatology , vol.36 , Issue.SUPPL. 1 , pp. 101
    • Ruiz, L.1    Valdez, A.2    Cotrina, M.3
  • 39
    • 0033067529 scopus 로고    scopus 로고
    • Mutational pattern of hepatitis B virus on sequential therapy with famciclovir and lamivudine in patients with hepatitis B virus reinfection occurring under HBIg immunoglobulin after liver transplantation
    • Tillmann HL, Trautwein C, Bock T, et al. Mutational pattern of hepatitis B virus on sequential therapy with famciclovir and lamivudine in patients with hepatitis B virus reinfection occurring under HBIg immunoglobulin after liver transplantation. Hepatology 1999; 30:244-56.
    • (1999) Hepatology , vol.30 , pp. 244-256
    • Tillmann, H.L.1    Trautwein, C.2    Bock, T.3
  • 40
    • 2942559300 scopus 로고    scopus 로고
    • A multicenter United States-Canadian trial to assess lamivudine monotherapy before and after liver transplantation for chronic hepatitis B
    • Perrillo RP, Wright T, Rakela J, et al. A multicenter United States-Canadian trial to assess lamivudine monotherapy before and after liver transplantation for chronic hepatitis B. Hepatology 2001; 33:424-32.
    • (2001) Hepatology , vol.33 , pp. 424-432
    • Perrillo, R.P.1    Wright, T.2    Rakela, J.3
  • 41
    • 0034068988 scopus 로고    scopus 로고
    • Outcome of lamivudine resistant hepatitis B virus infection in the liver transplant recipient
    • Mutimer D, Pillay D, Shields P, et al. Outcome of lamivudine resistant hepatitis B virus infection in the liver transplant recipient. Gut 2000; 46:107-13.
    • (2000) Gut , vol.46 , pp. 107-113
    • Mutimer, D.1    Pillay, D.2    Shields, P.3
  • 42
    • 0034235905 scopus 로고    scopus 로고
    • Adefovir dipivoxil for the treatment of lamivudine-resistant hepatitis B mutants
    • Perrillo R, Schiff E, Yoshida E, et al. Adefovir dipivoxil for the treatment of lamivudine-resistant hepatitis B mutants. Hepatology 2000; 32:129-34.
    • (2000) Hepatology , vol.32 , pp. 129-134
    • Perrillo, R.1    Schiff, E.2    Yoshida, E.3
  • 43
    • 0000349339 scopus 로고    scopus 로고
    • GS-98-437: A double-blind, randomized, placebo-controlled study of adefovir dipivoxil (ADV) for the treatment of patients with HBeAg+ chronic hepatitis B infection: 48 Week results
    • abstract 340A
    • Marcellin P, Chang T-T, Lim SG, et al. GS-98-437: a double-blind, randomized, placebo-controlled study of adefovir dipivoxil (ADV) for the treatment of patients with HBeAg+ chronic hepatitis B infection: 48 week results [abstract 340A]. Hepatology 2001; 34:671.
    • (2001) Hepatology , vol.34 , pp. 671
    • Marcellin, P.1    Chang, T.-T.2    Lim, S.G.3
  • 44
    • 0001335433 scopus 로고    scopus 로고
    • Adefovir dipivoxil (ADV) alone and in combination with lamivudine (LAM) suppresses LAM-resistant hepatitis B virus (HBV) replication: 16 Week interim analysis
    • abstract 13
    • Peters M, Hann HW, Martin P, et al. Adefovir dipivoxil (ADV) alone and in combination with lamivudine (LAM) suppresses LAM-resistant hepatitis B virus (HBV) replication: 16 week interim analysis [abstract 13]. J Hepatology 2002; 36(Suppl 1):6.
    • (2002) J Hepatology , vol.36 , Issue.SUPPL. 1 , pp. 6
    • Peters, M.1    Hann, H.W.2    Martin, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.