Mitochondrial tRNA sequences as unusual replication origins: Pathogenic implications for Homo sapiens

Journal of Theoretical Biology

Volumn 243, Issue 3, 2006, Pages 375-385

  Seligmann, Hervé ^a   Krishnan, Neeraja M ^b   Rao, Basuthkar J ^b  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

Author keywords

Aging; Cumulative error; Functional duplication; Genome organization; Mutational robustness; Secondary structure; Substitution gradient

Indexed keywords

TRANSFER RNA;

GENE; GENOME; HOMINID; MUTATION; RNA;

ARTICLE; CONTROLLED STUDY; GENE FUNCTION; GENE LOCATION; GENE MUTATION; GENE REPLICATION; GENE SEQUENCE; GENE STRUCTURE; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MITOCHONDRION; MUTANT; PATHOGENESIS; PRIORITY JOURNAL; RNA REPLICATION; RNA TRANSCRIPTION; SIGN TEST;

AGING; DNA REPLICATION; GENOME; HUMANS; MITOCHONDRIA; MITOCHONDRIAL DISEASES; MODELS, GENETIC; MUTATION; RNA, TRANSFER; SEQUENCE HOMOLOGY; TRANSCRIPTION, GENETIC;

BACTERIA (MICROORGANISMS); HOMO SAPIENS; VERTEBRATA;

EID: 33750462751     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2006.06.028     Document Type: Article

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