The yeast counterparts of human 'MELAS' mutations cause mitochondrial dysfunction that can be rescued by overexpression of the mitochondrial translation factor EF-Tu

EMBO Reports

Volumn 4, Issue 1, 2003, Pages 53-58

  Feuermann, M ^a   Francisci, S ^b   Rinaldi, T ^b   De Luca, C ^b   Rohou, H ^a   Frontali, L ^b   Bolotin Fukuhara, M ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CYTOSINE; ELONGATION FACTOR TU; GUANINE; MITOCHONDRIAL RNA; TRANSFER RNA; MITOCHONDRIAL DNA;

ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; GENE CONSTRUCT; GENE DELETION; GENE MUTATION; GENE OVEREXPRESSION; GENETIC CODE; GENETIC POLYMORPHISM; HUMAN; MITOCHONDRIAL RESPIRATION; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RNA SEQUENCE; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS; MELAS SYNDROME; PHENOTYPE;

AMINO ACID SUBSTITUTION; BASE SEQUENCE; BIOLISTICS; DNA, MITOCHONDRIAL; GENE EXPRESSION REGULATION, FUNGAL; GENETIC VECTORS; HUMANS; MELAS SYNDROME; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; PEPTIDE ELONGATION FACTOR TU; PHENOTYPE; POINT MUTATION; PROTEIN BIOSYNTHESIS; RECOMBINANT FUSION PROTEINS; RNA, FUNGAL; RNA, TRANSFER, LEU; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0346666699     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.embor.embor713     Document Type: Article

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