Decreased ATP synthesis is phenotypically expressed during increased energy demand in fibroblasts containing mitochondrial tRNA mutations implications for neurodegenerative and mitochondrial DNA diseases

European Journal of Biochemistry

Volumn 259, Issue 1-2, 1999, Pages 462-469

  James, Andrew M ^a   Sheard, Philip W ^a   Wei, Yau Huei ^b   Murphy, Michael P ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b Box 56 ^*

Author keywords

ATP demand; Mitochondrial DNA, bioenergetic defect

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATE; GRAMICIDIN; MITOCHONDRIAL DNA; TRANSFER RNA;

ADOLESCENT; ADULT; ANIMAL CELL; ARTICLE; CELL DEATH; CHILD; CONTROLLED STUDY; DEGENERATIVE DISEASE; FIBROBLAST CULTURE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; MALE; MELAS SYNDROME; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MYOCLONUS EPILEPSY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADOLESCENT; ADULT; CELL DEATH; CELL MEMBRANE; CHILD, PRESCHOOL; FIBROBLASTS; HUMANS; INTRACELLULAR MEMBRANES; MALE; MELAS SYNDROME; MEMBRANE POTENTIALS; MERRF SYNDROME; MIDDLE AGED; MITOCHONDRIA; MODELS, BIOLOGICAL; MUTATION; PROTON-MOTIVE FORCE; RNA, TRANSFER; RNA, TRANSFER, LEU; RNA, TRANSFER, LYS;

ANIMALIA;

EID: 0033556240     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00066.x     Document Type: Article

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