메뉴 건너뛰기




Volumn 74, Issue 4, 1998, Pages 1808-1820

A permeant ion binding site located between two gates of the Shaker K+ channel

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL; BARIUM; POTASSIUM; RECOMBINANT PROTEIN; SHAKER POTASSIUM CHANNEL;

EID: 0031594195     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(98)77891-9     Document Type: Article
Times cited : (71)

References (51)
  • 1
    • 0028130350 scopus 로고
    • The P-region and S6 of Kv3.1 contribute to the formation of the ion conduction pathway
    • Aiyar, J., A. Nguyen, K. Chandy, and S. Grissmer. 1994. The P-region and S6 of Kv3.1 contribute to the formation of the ion conduction pathway. Biophys. J. 67:2261-2264.
    • (1994) Biophys. J. , vol.67 , pp. 2261-2264
    • Aiyar, J.1    Nguyen, A.2    Chandy, K.3    Grissmer, S.4
  • 3
    • 0015324606 scopus 로고
    • The inner quaternary ammonium ion receptor of potassium channels of the node of Ranvier
    • Armstrong, C., and B. Hille. 1972. The inner quaternary ammonium ion receptor of potassium channels of the node of Ranvier. J. Gen. Physiol. 59:388-400.
    • (1972) J. Gen. Physiol. , vol.59 , pp. 388-400
    • Armstrong, C.1    Hille, B.2
  • 4
    • 0020366556 scopus 로고
    • Block of squid axon potassium channels by internally and externally applied barium ions
    • Armstrong, C., R. Swenson, Jr., and S. Taylor. 1982. Block of squid axon potassium channels by internally and externally applied barium ions. J. Gen. Physiol. 80:663-682.
    • (1982) J. Gen. Physiol. , vol.80 , pp. 663-682
    • Armstrong, C.1    Swenson Jr., R.2    Taylor, S.3
  • 5
    • 0028793256 scopus 로고
    • Modulation of potassium current by frequency and external [K + ]: A tale of two inactivation mechanisms
    • Baukrowitz, T., and G. Yellen. 1995. Modulation of potassium current by frequency and external [K + ]: a tale of two inactivation mechanisms. Neuron. 15:951-960.
    • (1995) Neuron. , vol.15 , pp. 951-960
    • Baukrowitz, T.1    Yellen, G.2
  • 6
    • 0030031856 scopus 로고    scopus 로고
    • Use-dependent blockers and exit rate of the last ion from the multi-ion pore of a potassium channel
    • Baukrowiu, T., and O. Yellen. 1996. Use-dependent blockers and exit rate of the last ion from the multi-ion pore of a potassium channel. Science. 271:653-656.
    • (1996) Science , vol.271 , pp. 653-656
    • Baukrowiu, T.1    Yellen, O.2
  • 7
    • 0015424492 scopus 로고
    • Negative conductance caused by entry of sodium and cesium ions into the potassium channels of squid axons
    • Bezanilla, F., and C. Armstrong. 1972. Negative conductance caused by entry of sodium and cesium ions into the potassium channels of squid axons. J. Gen. Physiol. 60:588-608.
    • (1972) J. Gen. Physiol. , vol.60 , pp. 588-608
    • Bezanilla, F.1    Armstrong, C.2
  • 8
    • 0027417650 scopus 로고
    • The internal quaternary ammonium receptor site of Shaker potassium channels
    • Choi, K., C. Mossman, J. Aube, and G. Yellen. 1993. The internal quaternary ammonium receptor site of Shaker potassium channels. Neuron. 10:533-541.
    • (1993) Neuron. , vol.10 , pp. 533-541
    • Choi, K.1    Mossman, C.2    Aube, J.3    Yellen, G.4
  • 9
    • 0029977966 scopus 로고    scopus 로고
    • Structural model of the outer vestibule and selectivity filter of the Shaker voltage-gated potassium channel
    • Durell, S., and H. Guy. 1996. Structural model of the outer vestibule and selectivity filter of the Shaker voltage-gated potassium channel. Neuropharmarology. 35:761-773.
    • (1996) Neuropharmarology , vol.35 , pp. 761-773
    • Durell, S.1    Guy, H.2
  • 10
    • 0028276482 scopus 로고
    • + channel: Peptide and channel residues mediating molecular recognition
    • + channel: peptide and channel residues mediating molecular recognition. Neuron. 12:1377-1388.
    • (1994) Neuron. , vol.12 , pp. 1377-1388
    • Goldstein, S.1    Pheasant, D.2    Miller, C.3
  • 11
    • 0029902634 scopus 로고    scopus 로고
    • Hydrophobic mutations alter the movement of magnesium in the pore of voltage-gated potassium channels
    • Harris, R., and E. Isacoff. 1996. Hydrophobic mutations alter the movement of magnesium in the pore of voltage-gated potassium channels. Biophys. J. 71:209-219.
    • (1996) Biophys. J. , vol.71 , pp. 209-219
    • Harris, R.1    Isacoff, E.2
  • 12
    • 0025862997 scopus 로고
    • Exchange of conduction pathways between two related potassium channels
    • Hartmann, H., G. Kirsh, J. Drewe, M. Taglialatela, R. Joho, and A. Brown. 1991. Exchange of conduction pathways between two related potassium channels. Science. 251:942-944.
    • (1991) Science , vol.251 , pp. 942-944
    • Hartmann, H.1    Kirsh, G.2    Drewe, J.3    Taglialatela, M.4    Joho, R.5    Brown, A.6
  • 16
    • 0028987938 scopus 로고
    • + channel pore through mutant cycles with a peptide inhibitor
    • + channel pore through mutant cycles with a peptide inhibitor. Science. 268:307-310.
    • (1995) Science , vol.268 , pp. 307-310
    • Hidalgo, P.1    MacKinnon, R.2
  • 18
    • 33748263658 scopus 로고
    • The potassium permeability of a giant nerve fibre
    • Hodgkin, A., and R. Keynes. 1955. The potassium permeability of a giant nerve fibre. J. Physiol. (Lond.). 128:61-88.
    • (1955) J. Physiol. (Lond.) , vol.128 , pp. 61-88
    • Hodgkin, A.1    Keynes, R.2
  • 19
    • 0025224223 scopus 로고
    • Biophysical and molecular mechanisms of Shaker potassium channel inactivation
    • Hoshi, T., W. Zagotta, and R. Aldrich. 1990. Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science. 250:533-538.
    • (1990) Science , vol.250 , pp. 533-538
    • Hoshi, T.1    Zagotta, W.2    Aldrich, R.3
  • 20
    • 0029587218 scopus 로고
    • External barium block of Shaker potassium channels: Evidence for two binding sites
    • Hurst, R., R. Latorre, L. Toro, and E. Stefani. 1995. External barium block of Shaker potassium channels: evidence for two binding sites. J. Gen. Physiol. 106:1069-1087.
    • (1995) J. Gen. Physiol. , vol.106 , pp. 1069-1087
    • Hurst, R.1    Latorre, R.2    Toro, L.3    Stefani, E.4
  • 21
    • 0029896356 scopus 로고    scopus 로고
    • Molecular determinants of external barium block in Shaker potassium channels
    • Hurst, R., L. Toro, and E. Stefani. 1996. Molecular determinants of external barium block in Shaker potassium channels. FEBS Lett. 388:59-65.
    • (1996) FEBS Lett. , vol.388 , pp. 59-65
    • Hurst, R.1    Toro, L.2    Stefani, E.3
  • 23
    • 0344650964 scopus 로고
    • A site near the transmembrane segment S6 of potassium channels interacts with barium ions
    • Isacoff, E., G. Lope, Y. Jan, and L. Jan. 1993. A site near the transmembrane segment S6 of potassium channels interacts with barium ions. Biophys. J. 64:A226.
    • (1993) Biophys. J. , vol.64
    • Isacoff, E.1    Lope, G.2    Jan, Y.3    Jan, L.4
  • 25
    • 0028941130 scopus 로고
    • Side-chain accessibilities in the pore of a potassium channel probed by sulfhydryl-specific reagents after cysteine-scanning mutagenesis
    • Kurz, L., and R. Zulke, H. Zhang, and R. Joho. 1995. Side-chain accessibilities in the pore of a potassium channel probed by sulfhydryl-specific reagents after cysteine-scanning mutagenesis. Biophys. J. 68:900-905.
    • (1995) Biophys. J. , vol.68 , pp. 900-905
    • Kurz, L.1    Zulke, R.2    Zhang, H.3    Joho, R.4
  • 26
    • 0029990996 scopus 로고    scopus 로고
    • Dynamic rearrangement of the outer mouth of a potassium channel during gating
    • Liu, Y., M. Jurman, and G. Yellen. 1996. Dynamic rearrangement of the outer mouth of a potassium channel during gating. Neuron. 16:859-867.
    • (1996) Neuron. , vol.16 , pp. 859-867
    • Liu, Y.1    Jurman, M.2    Yellen, G.3
  • 28
    • 0027828292 scopus 로고
    • Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels
    • Lopez-Barneo, J., T. Hoshi, S. Heinemann, and R. Aldrich. 1993. Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels. Receptors Channels. 1:61-71.
    • (1993) Receptors Channels , vol.1 , pp. 61-71
    • Lopez-Barneo, J.1    Hoshi, T.2    Heinemann, S.3    Aldrich, R.4
  • 29
    • 0028960949 scopus 로고
    • Silver as a probe of pore-forming residues in a potassium channel
    • Lu, Q., and C. Miller. 1995. Silver as a probe of pore-forming residues in a potassium channel. Science. 268:304-307.
    • (1995) Science , vol.268 , pp. 304-307
    • Lu, Q.1    Miller, C.2
  • 30
    • 0025644364 scopus 로고
    • Mapping the receptor site for charybdotoxin, a pore-blocking potassium channel inhibitor
    • MacKinnon, R., L. Heginbotham, and T. Abramson. 1990. Mapping the receptor site for charybdotoxin, a pore-blocking potassium channel inhibitor. Neuron. 5:767-771.
    • (1990) Neuron. , vol.5 , pp. 767-771
    • MacKinnon, R.1    Heginbotham, L.2    Abramson, T.3
  • 31
    • 0024426645 scopus 로고
    • Mutant potassium channels with altered binding of charybdotoxin, a pore-blocking peptide inhibitor
    • MacKinnon, R., and C. Miller. 1989. Mutant potassium channels with altered binding of charybdotoxin, a pore-blocking peptide inhibitor. Science. 245:1382-1385.
    • (1989) Science , vol.245 , pp. 1382-1385
    • MacKinnon, R.1    Miller, C.2
  • 32
    • 0025706152 scopus 로고
    • Mutations affecting TEA blockade and ion permeation in voltage-activated potassium channels
    • MacKinnon, R., and G. Yellen. 1990. Mutations affecting TEA blockade and ion permeation in voltage-activated potassium channels. Science. 250:276-279.
    • (1990) Science , vol.250 , pp. 276-279
    • MacKinnon, R.1    Yellen, G.2
  • 33
    • 0023369648 scopus 로고
    • Trapping single ions inside single ion channels
    • Miller, C. 1987. Trapping single ions inside single ion channels. Biophys. J. 52:123-126.
    • (1987) Biophys. J. , vol.52 , pp. 123-126
    • Miller, C.1
  • 34
    • 0023506099 scopus 로고
    • Coupling of voltage-dependent gating and barium block in the high conductance, calcium-activated K + channel
    • Miller, C., R. Latorre, and I. Reisin. 1987. Coupling of voltage-dependent gating and barium block in the high conductance, calcium-activated K + channel. J. Gen. Physiol. 90:427-449.
    • (1987) J. Gen. Physiol. , vol.90 , pp. 427-449
    • Miller, C.1    Latorre, R.2    Reisin, I.3
  • 35
    • 0030993829 scopus 로고    scopus 로고
    • Pore mutations in Shaker potassium channels distinguish between the sites of TEA blockade and C-type inactivation
    • Molina, A., A. Castellano, and J. Lopez-Barneo. 1997. Pore mutations in Shaker potassium channels distinguish between the sites of TEA blockade and C-type inactivation. J. Physiol. (Lond.). 499:361-367.
    • (1997) J. Physiol. (Lond.) , vol.499 , pp. 361-367
    • Molina, A.1    Castellano, A.2    Lopez-Barneo, J.3
  • 36
    • 0030044863 scopus 로고    scopus 로고
    • A strongly interacting pair of residues on the contact surface of charybdotoxin and a Shaker potassium channel
    • Naranjo, D., and C. Miller. 1996. A strongly interacting pair of residues on the contact surface of charybdotoxin and a Shaker potassium channel. Neuron. 16:123-130.
    • (1996) Neuron. , vol.16 , pp. 123-130
    • Naranjo, D.1    Miller, C.2
  • 37
    • 0023709415 scopus 로고
    • Potassium blocks barium permeation through a calcium-activated potassium channel
    • Neyton, J., and C. Miller. 1988a. Potassium blocks barium permeation through a calcium-activated potassium channel. J. Gen. Physiol. 92:549-567.
    • (1988) J. Gen. Physiol. , vol.92 , pp. 549-567
    • Neyton, J.1    Miller, C.2
  • 38
    • 0023823843 scopus 로고
    • Discrete barium block as a probe of ion occupancy and pore structure in the high-conductance calcium-activated potassium channel
    • Neyton, J., and C. Miller. 1988b. Discrete barium block as a probe of ion occupancy and pore structure in the high-conductance calcium-activated potassium channel. J. Gen. Physiol. 92:569-586.
    • (1988) J. Gen. Physiol. , vol.92 , pp. 569-586
    • Neyton, J.1    Miller, C.2
  • 39
    • 0026021482 scopus 로고
    • Multi-ion occupancy alters gating in high-conductance, calcium activated potassium channels
    • Neyton, J., and M. Pelleschi. 1991. Multi-ion occupancy alters gating in high-conductance, calcium activated potassium channels. J. Gen. Physiol 97:641-665.
    • (1991) J. Gen. Physiol , vol.97 , pp. 641-665
    • Neyton, J.1    Pelleschi, M.2
  • 40
    • 0029070117 scopus 로고
    • + pore structure revealed by reporter cysteines at inner and outer surfaces
    • + pore structure revealed by reporter cysteines at inner and outer surfaces. Neuron. 14:1055-1063.
    • (1995) Neuron. , vol.14 , pp. 1055-1063
    • Pascual, J.M.1    Shieh, C.2    Kirsch, G.3    Brown, A.4
  • 41
    • 0030064382 scopus 로고    scopus 로고
    • Spatial localization of the potassium channel selectivity filter by mutant cycle-based structure analysis
    • Ranganathan, R., J. Lewis, and R. MacKinnon. 1996. Spatial localization of the potassium channel selectivity filter by mutant cycle-based structure analysis. Neuron. 16:131-139.
    • (1996) Neuron. , vol.16 , pp. 131-139
    • Ranganathan, R.1    Lewis, J.2    MacKinnon, R.3
  • 43
    • 0027445510 scopus 로고
    • The S4-S5 loop contributes to the ion-selective pore of potassium channels
    • Slesinger, P., Y. Jan, and L. Jan. 1993. The S4-S5 loop contributes to the ion-selective pore of potassium channels. Neuron. 11:739-749.
    • (1993) Neuron. , vol.11 , pp. 739-749
    • Slesinger, P.1    Jan, Y.2    Jan, L.3
  • 44
    • 0030009740 scopus 로고    scopus 로고
    • + fluxes through recombinant Shaker potassium channels expressed in single Xenopus oocytes
    • + fluxes through recombinant Shaker potassium channels expressed in single Xenopus oocytes. J. Gen. Physiol. 107:449-457.
    • (1996) J. Gen. Physiol. , vol.107 , pp. 449-457
    • Stampe, P.1    Begenisich, T.2
  • 46
    • 0015879604 scopus 로고
    • Ionic blockage of sodium channels in nerve
    • Woodhull, A. 1973. Ionic blockage of sodium channels in nerve. J Gen. Physiol. 61:687-708.
    • (1973) J Gen. Physiol. , vol.61 , pp. 687-708
    • Woodhull, A.1
  • 47
    • 0021137261 scopus 로고
    • 2+ channels by external cations
    • 2+ channels by external cations. J. Gen. Physiol. 84:187-199.
    • (1984) J. Gen. Physiol. , vol.84 , pp. 187-199
    • Yellen, G.1
  • 48
    • 0025800956 scopus 로고
    • Mutations affecting internal TEA blockade identify the probable pore-forming region of a potassium channel
    • Yellen, G., M. Jurman, T. Abramson, and R. MacKinnon. 1991. Mutations affecting internal TEA blockade identify the probable pore-forming region of a potassium channel. Science. 251:939-942.
    • (1991) Science , vol.251 , pp. 939-942
    • Yellen, G.1    Jurman, M.2    Abramson, T.3    MacKinnon, R.4
  • 49
    • 0028297301 scopus 로고
    • An engineered cysteine in the external mouth of a potassium channel allows inactivalion to be modulated by metal binding
    • Yellen, G., D. Sodickson, T. Chen, and M. Jurman. 1994. An engineered cysteine in the external mouth of a potassium channel allows inactivalion to be modulated by metal binding. Biophys. J. 66:1068-1075.
    • (1994) Biophys. J. , vol.66 , pp. 1068-1075
    • Yellen, G.1    Sodickson, D.2    Chen, T.3    Jurman, M.4
  • 50
    • 0026058182 scopus 로고
    • Alteration of ionic selectivity of a potassium channel by mutation of the H5 region
    • Yool, A., and T. Schwarz. 1991. Alteration of ionic selectivity of a potassium channel by mutation of the H5 region. Nature. 349:700-704.
    • (1991) Nature , vol.349 , pp. 700-704
    • Yool, A.1    Schwarz, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.