Interaction between fast and ultra-slow inactivation in the voltage-gated sodium channel. Does the inactivation gate stabilize the channel structure?

Journal of Biological Chemistry

Volumn 277, Issue 40, 2002, Pages 37105-37115

  Hilber, Karlheinz ^a   Sandtner, Walter ^b   Kudlacek, Oliver ^c   Schreiner, Blanca ^d   Glaaser, Ian ^a,b   Schütz, Wolfgang ^a   Fozzard, Harry A ^d   Dudley, Samuel C ^b   Todt, Hannes ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF CHICAGO   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d ATLANTA VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; MUTAGENESIS; SODIUM;

MUTATIONS; SODIUM CHANNELS;

MUSCLE;

CONOTOXIN; PEPTIDE; SODIUM CHANNEL;

ARTICLE; CONTROLLED STUDY; DEPOLARIZATION; ELECTRIC POTENTIAL; FEMALE; GENE EXPRESSION; GENE MUTATION; HYPOTHESIS; MUTANT; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; RAT; REDUCTION; VESTIBULE;

AMINO ACID SUBSTITUTION; ANIMALS; BRAIN; ELECTROPHYSIOLOGY; ION CHANNEL GATING; KINETICS; MEMBRANE POTENTIALS; MODELS, MOLECULAR; MUSCLE, SKELETAL; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN CONFORMATION; PROTEIN SUBUNITS; RATS;

EID: 0037020086     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M205661200     Document Type: Article

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