The C677T polymorphism in the methylenetetrahydrofolate reductase gene (MTHFR), maternal use of folic acid supplements, and risk of isolated clubfoot: A case-parent-triad analysis

American Journal of Epidemiology

Volumn 164, Issue 9, 2006, Pages 852-861

  Sharp, Linda ^a   Miedzybrodzka, Zosia ^b   Cardy, Amanda H ^b   Inglis, Julie ^b   Madrigal, Londale ^b   Barker, Simon ^c   Chesney, David ^d   Clark, Caroline ^b   Maffulli, Nicola ^e  

^a NATIONAL CANCER REGISTRY IRELAND   (Ireland)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c UNIVERSITY OF ABERDEEN   (United Kingdom)

^d FREEMAN HOSPITAL   (United Kingdom)

^e KEELE UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

5,10 methylenetetrahydrofolate reductase (FADH2); Clubfoot; Dietary supplements; Folic acid; Genes; Polymorphism, genetic; Pregnancy

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); FOLIC ACID;

CHILD HEALTH; DISEASE; ENVIRONMENTAL FACTOR; ENZYME; GENE; GENETICS; HEALTH RISK; POLYMORPHISM; PREGNANCY; VITAMIN;

ARTICLE; CLUBFOOT; CONFIDENCE INTERVAL; DEMOGRAPHY; DNA SYNTHESIS; FEMALE; FOLATE METABOLISM; GENETIC POLYMORPHISM; HUMAN; MAJOR CLINICAL STUDY; MALE; PREGNANCY; RISK FACTOR; SUPPLEMENTATION;

ADOLESCENT; ADULT; ALCOHOL DRINKING; CLUBFOOT; DNA; FEMALE; FOLIC ACID; GENETICS, POPULATION; GENOTYPE; HUMANS; LINEAR MODELS; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; POLYMORPHISM, GENETIC; RISK; VITAMIN B COMPLEX;

EURASIA; EUROPE; UNITED KINGDOM; WESTERN EUROPE;

EID: 33750298973     PISSN: 00029262     EISSN: 14766256     Source Type: Journal    
DOI: 10.1093/aje/kwj285     Document Type: Article

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