The 5,10-methylenetetrahydrofolate reductase C677T polymorphism interacts with smoking to increase homocysteine

Atherosclerosis

Volumn 174, Issue 2, 2004, Pages 315-322

  Brown, Karen S ^a   Kluijtmans, Leo A J ^b   Young, Ian S ^c   Murray, Liam ^c   McMaster, Dorothy ^c   Woodside, Jayne V ^c   Yarnell, John W G ^c   Boreham, Colin A ^d   McNulty, Helene ^d   Strain, J J ^d   McPartlin, Joseph ^e   Scott, John M ^e   Mitchell, Laura E ^f   Whitehead, Alexander S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^d UNIVERSITY OF ULSTER   (United Kingdom)

^e TRINITY COLLEGE DUBLIN   (Ireland)

^f UNIVERSITY OF TEXAS   (United States)

Author keywords

5,10 Methylenetetrahydrofolate reductase; Folate; Hyperhomocysteinemia; Nitric oxide; Nitric oxide synthase; Smoking

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); FOLIC ACID; HOMOCYSTEINE; NITRIC OXIDE; SYNTHETASE;

ADULT; ARTICLE; CATABOLISM; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; ERYTHROCYTE; FEMALE; FOLIC ACID BLOOD LEVEL; FOLIC ACID DEFICIENCY; GENDER; GENETIC POLYMORPHISM; GENOTYPE; HOMOZYGOSITY; HOMOZYGOTE; HUMAN; HYPERHOMOCYSTEINEMIA; MALE; NORMAL HUMAN; NUTRITIONAL VALUE; POPULATION; PRIORITY JOURNAL; RISK ASSESSMENT; SERUM; SMOKING;

ADULT; COHORT STUDIES; FEMALE; FOLIC ACID; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; HYPERHOMOCYSTEINEMIA; LINEAR MODELS; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); POLYMORPHISM, GENETIC; PROBABILITY; RISK ASSESSMENT; SMOKING;

EID: 2342528999     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2004.01.023     Document Type: Article

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