-
1
-
-
0000167774
-
Disorder of transsulfuration
-
Scriver CR, Beaudet AL, Sly WS, Valle D, Scriver CR, Beaudet AL, Sly WS, Valles D (eds). New York, NY, McGraw-Hill
-
Mudd SH, Levy HL, Skovby F: Disorder of transsulfuration, in Scriver CR, Beaudet AL, Sly WS, Valle D, Scriver CR, Beaudet AL, Sly WS, Valles D (eds): The Metabolic Basis of Inherited Disease. New York, NY, McGraw-Hill, 1995, p 1279
-
(1995)
The Metabolic Basis of Inherited Disease
, pp. 1279
-
-
Mudd, S.H.1
Levy, H.L.2
Skovby, F.3
-
2
-
-
0014545138
-
Vascular pathology of homocysteinemia
-
McCully KS: Vascular pathology of homocysteinemia. Am J Pathol 56:111, 1969
-
(1969)
Am J Pathol
, vol.56
, pp. 111
-
-
McCully, K.S.1
-
3
-
-
0017284939
-
The pathogenesis of coronary artery disease: A possible role for methionine metabolism
-
Wilcken DEL, Wilcken B: The pathogenesis of coronary artery disease: A possible role for methionine metabolism. J Clin Invest 57:1079, 1976
-
(1976)
J Clin Invest
, vol.57
, pp. 1079
-
-
Wilcken, D.E.L.1
Wilcken, B.2
-
4
-
-
0001010968
-
Plasma homocysteine and vascular disease
-
Francis RB Jr (ed): New York, NY, Marcel Dekker
-
Ueland PM, Refsum H, Brattstrom L: Plasma homocysteine and vascular disease, in Francis RB Jr (ed): Atherosclerotic Cardiovascular Disease. Haemostasis and Endothelial Function. New York, NY, Marcel Dekker, 1992, p 183
-
(1992)
Atherosclerotic Cardiovascular Disease. Haemostasis and Endothelial Function
, vol.183
-
-
Ueland, P.M.1
Refsum, H.2
Brattstrom, L.3
-
5
-
-
0030971062
-
Homocysteine and thrombotic disease
-
D'Angelo A, Selhub J: Homocysteine and thrombotic disease. Blood 90:1, 1997
-
(1997)
Blood
, vol.90
, pp. 1
-
-
D'Angelo, A.1
Selhub, J.2
-
6
-
-
0030797307
-
Hyperhomocysteinemia as a risk factor for arterial and venous disease. A review of evidence and relevance
-
Boers GHJ: Hyperhomocysteinemia as a risk factor for arterial and venous disease. A review of evidence and relevance. Thromb Haemost 77:520, 1997
-
(1997)
Thromb Haemost
, vol.77
, pp. 520
-
-
Boers, G.H.J.1
-
7
-
-
0029066299
-
A quantitative assessement of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes
-
Boushey CJ, Beresford SAA, Omenn GS, Motulsky AG: A quantitative assessement of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA 274:1049, 1995
-
(1995)
JAMA
, vol.274
, pp. 1049
-
-
Boushey, C.J.1
Beresford, S.A.A.2
Omenn, G.S.3
Motulsky, A.G.4
-
8
-
-
1842370239
-
Plasma homocysteine levels and mortality in patients with coronary artery disease
-
Nygård O, Nordrehaug JE, Refsum E, Ueland PM, Farstad M, Vollset SE: Plasma homocysteine levels and mortality in patients with coronary artery disease. N Engl J Med 337:230, 1997
-
(1997)
N Engl J Med
, vol.337
, pp. 230
-
-
Nygård, O.1
Nordrehaug, J.E.2
Refsum, E.3
Ueland, P.M.4
Farstad, M.5
Vollset, S.E.6
-
9
-
-
0023696435
-
Intermediate homocysteinemia: A thermolabile variant of methylenetetrahydrofolate reductase
-
Kang S-S, Zhou J, Wong PWK, Kowalisyn J, Strokosch G: Intermediate homocysteinemia: A thermolabile variant of methylenetetrahydrofolate reductase. Am J Hum Genet 43:414, 1988
-
(1988)
Am J Hum Genet
, vol.43
, pp. 414
-
-
Kang, S.-S.1
Zhou, J.2
Wong, P.W.K.3
Kowalisyn, J.4
Strokosch, G.5
-
10
-
-
0027421353
-
Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease
-
Kang S-S, Passen EL, Ruggie N, Wong PWK, Sora H: Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease. Circulation 88:1463, 1993
-
(1993)
Circulation
, vol.88
, pp. 1463
-
-
Kang, S.-S.1
Passen, E.L.2
Ruggie, N.3
Wong, P.W.K.4
Sora, H.5
-
11
-
-
0029049553
-
Identification of a candidate genetic risk factor for vascular disease: A common mutation at the methylenetetrahydrofolate reductase locus
-
Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, Boers GHJ, den Heijer M, Kluijtmans LAJ, van den Heuvel LP, Rozen R: Identification of a candidate genetic risk factor for vascular disease: A common mutation at the methylenetetrahydrofolate reductase locus. Nat Genet 10:111, 1995
-
(1995)
Nat Genet
, vol.10
, pp. 111
-
-
Frosst, P.1
Blom, H.J.2
Milos, R.3
Goyette, P.4
Sheppard, C.A.5
Matthews, R.G.6
Boers, G.H.J.7
Den Heijer, M.8
Kluijtmans, L.A.J.9
Van Den Heuvel, L.P.10
Rozen, R.11
-
12
-
-
0030811925
-
Genetic predisposition to hyperhomocysteinemia: Deficiency of methylenetetrahydrofolate reductase (MTHFR)
-
Rozen R: Genetic predisposition to hyperhomocysteinemia: Deficiency of methylenetetrahydrofolate reductase (MTHFR). Thromb Haemost 77:523, 1997
-
(1997)
Thromb Haemost
, vol.77
, pp. 523
-
-
Rozen, R.1
-
13
-
-
0030027668
-
Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations
-
Jacques PF, Bostom AG, Williams RR, Ellison RC, Eckfeldt JH, Rosenberg IH, Selhub J, Rozen R: Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation 93:7, 1996
-
(1996)
Circulation
, vol.93
, pp. 7
-
-
Jacques, P.F.1
Bostom, A.G.2
Williams, R.R.3
Ellison, R.C.4
Eckfeldt, J.H.5
Rosenberg, I.H.6
Selhub, J.7
Rozen, R.8
-
14
-
-
0023628783
-
Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection
-
Araki A, Sako Y: Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection. J Chromatogr 422:43, 1987
-
(1987)
J Chromatogr
, vol.422
, pp. 43
-
-
Araki, A.1
Sako, Y.2
-
15
-
-
0029655724
-
Molecular genetic analysis in mild hyperhomocysteinemia: A common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease
-
Kluijtmans LAJ, Van den Heuvel LPWJ, Boers GHJ, Frosst P, Van Oost BA, den Heijer M, Stevens EMB, Trijbels JMF, Rozen R, Blom HJ: Molecular genetic analysis in mild hyperhomocysteinemia: A common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am J Hum Genet 58:35, 1996
-
(1996)
Am J Hum Genet
, vol.58
, pp. 35
-
-
Kluijtmans, L.A.J.1
Van Den Heuvel, L.P.W.J.2
Boers, G.H.J.3
Frosst, P.4
Van Oost, B.A.5
Den Heijer, M.6
Stevens, E.M.B.7
Trijbels, J.M.F.8
Rozen, R.9
Blom, H.J.10
-
16
-
-
0029827313
-
Homocysteine and risk of premature coronary heart disease. Evidence for a common gene mutation
-
Gallagher PM, Meleady R, Shields DC, Soon Tan K, McMaster D, Rozen R, Evans A, Graham IM, Whitehead AS: Homocysteine and risk of premature coronary heart disease. Evidence for a common gene mutation. Circulation 94:2154, 1996
-
(1996)
Circulation
, vol.94
, pp. 2154
-
-
Gallagher, P.M.1
Meleady, R.2
Shields, D.C.3
Soon Tan, K.4
McMaster, D.5
Rozen, R.6
Evans, A.7
Graham, I.M.8
Whitehead, A.S.9
-
17
-
-
0030897112
-
Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease
-
Morita H, Taguchi J, Kurihara H, Kitaoka M, Kaneda H, Kurihara Y, Maemura K, Shindo T, Minamino T, Ohno M, Yamaoki, Ogasawara K, Aizawa T, Suzuki S, Yazaki Y: Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease. Circulation 95:2032, 1997
-
(1997)
Circulation
, vol.95
, pp. 2032
-
-
Morita, H.1
Taguchi, J.2
Kurihara, H.3
Kitaoka, M.4
Kaneda, H.5
Kurihara, Y.6
Maemura, K.7
Shindo, T.8
Minamino, T.9
Ohno, M.10
Yamaoki11
Ogasawara, K.12
Aizawa, T.13
Suzuki, S.14
Yazaki, Y.15
-
18
-
-
0029975240
-
Genetic analysis of thermolabile methylenetetrahydrofolate reductase as a risk factor for myocardial infarction
-
Adams M, Smith PD, Martin D, Thompson JR, Lodwick D, Samani NJ: Genetic analysis of thermolabile methylenetetrahydrofolate reductase as a risk factor for myocardial infarction. Q J Med 89:437, 1996
-
(1996)
Q J Med
, vol.89
, pp. 437
-
-
Adams, M.1
Smith, P.D.2
Martin, D.3
Thompson, J.R.4
Lodwick, D.5
Samani, N.J.6
-
19
-
-
0029806746
-
Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians
-
Ma J, Stampfer MJ, Hennekens CH, Frosst P, Selhub J, Horsford J, Malinow MR, Willett WC, Rozen R: Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. Circulation 94:2410, 1996
-
(1996)
Circulation
, vol.94
, pp. 2410
-
-
Ma, J.1
Stampfer, M.J.2
Hennekens, C.H.3
Frosst, P.4
Selhub, J.5
Horsford, J.6
Malinow, M.R.7
Willett, W.C.8
Rozen, R.9
-
20
-
-
0030811670
-
Myocardial infarction in young women in relation to plasma total homocysteine, folate, and a common variant in the methylenetetrahydrofolate reductase gene
-
Schwartz SM, Siscovick DS, Malinow RM, Rosendaal FR, Beverly RK, Hess DL, Psaty BM, Longstreth WT, Koepsell TD, Raughunathan TE, Reitsma PH: Myocardial infarction in young women in relation to plasma total homocysteine, folate, and a common variant in the methylenetetrahydrofolate reductase gene. Circulation 96:412, 1997
-
(1997)
Circulation
, vol.96
, pp. 412
-
-
Schwartz, S.M.1
Siscovick, D.S.2
Malinow, R.M.3
Rosendaal, F.R.4
Beverly, R.K.5
Hess, D.L.6
Psaty, B.M.7
Longstreth, W.T.8
Koepsell, T.D.9
Raughunathan, T.E.10
Reitsma, P.H.11
-
21
-
-
0029968008
-
Genetic polymorphysm of methylenetetrahydrofolate reductase and myocardial infarction. A case control study
-
Schmitz C, Lindpaintner K, Verhoef P, Graziano JM, Buring J: Genetic polymorphysm of methylenetetrahydrofolate reductase and myocardial infarction. A case control study. Circulation 94:1812, 1996
-
(1996)
Circulation
, vol.94
, pp. 1812
-
-
Schmitz, C.1
Lindpaintner, K.2
Verhoef, P.3
Graziano, J.M.4
Buring, J.5
-
22
-
-
0031049530
-
A common mutation in methylenetetrahydrofolate reductase gene is not a major risk factor of coronary artery disease or myocardial infarction
-
Brugada R, Marian J: A common mutation in methylenetetrahydrofolate reductase gene is not a major risk factor of coronary artery disease or myocardial infarction. Atherosclerosis 128:107, 1997
-
(1997)
Atherosclerosis
, vol.128
, pp. 107
-
-
Brugada, R.1
Marian, J.2
-
23
-
-
0030934392
-
Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease
-
Christensen B, Frosst P, Lussier-Cacan S, Shelub J, Goyette P, Rosenblatt DS, Genest J, Rozen R: Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease. Arterioscler Thromb Vase Biol 17:569, 1997
-
(1997)
Arterioscler Thromb Vase Biol
, vol.17
, pp. 569
-
-
Christensen, B.1
Frosst, P.2
Lussier-Cacan, S.3
Shelub, J.4
Goyette, P.5
Rosenblatt, D.S.6
Genest, J.7
Rozen, R.8
-
24
-
-
0031025577
-
Methylenetetrahydrofolate reductase gene and coronary artery disease
-
van Bockxmeer FM, Mamotte CD, Vasikaran SD, Taylor RR: Methylenetetrahydrofolate reductase gene and coronary artery disease. Circulation 95:21, 1997
-
(1997)
Circulation
, vol.95
, pp. 21
-
-
Bockxmeer, F.M.1
Mamotte, C.D.2
Vasikaran, S.D.3
Taylor, R.R.4
-
26
-
-
0030612756
-
The 677 C→T mutation in the methylenetetrahydrofolate reductase gene: Associations with plasma total homocysteine levels and risk of coronary atherosclerotic disease
-
Verhoef P, Kok FJ, Kluijtmans LAJ, Blom HJ, Refsum H, Ueland PM, Kruyssen DACM: The 677 C→T mutation in the methylenetetrahydrofolate reductase gene: Associations with plasma total homocysteine levels and risk of coronary atherosclerotic disease. Atherosclerosis 132:105, 1997
-
(1997)
Atherosclerosis
, vol.132
, pp. 105
-
-
Verhoef, P.1
Kok, F.J.2
Kluijtmans, L.A.J.3
Blom, H.J.4
Refsum, H.5
Ueland, P.M.6
Kruyssen, D.A.C.M.7
-
27
-
-
0029655527
-
Nutritional ecogenetics: Homocysteine-related aneriosclerotic vascular disease, neural tube defects, and folic acid
-
Motulsky AG: Nutritional ecogenetics: Homocysteine-related aneriosclerotic vascular disease, neural tube defects, and folic acid. Am J Hum Genet 58:17, 1996
-
(1996)
Am J Hum Genet
, vol.58
, pp. 17
-
-
Motulsky, A.G.1
-
28
-
-
0028844492
-
Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida
-
van der Put NMJ, Steegers-Theunissen RPM, Frosst P, Trijbels FJM, Eskes TKAB, van den Heuvel LP, Mariman ECM, den Heijer M, Rozen R, Blom HJ: Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida. Lancet 346:1070, 1995
-
(1995)
Lancet
, vol.346
, pp. 1070
-
-
Van Der Put, N.M.J.1
Steegers-Theunissen, R.P.M.2
Frosst, P.3
Trijbels, F.J.M.4
Eskes, T.K.A.B.5
Van Den Heuvel, L.P.6
Mariman, E.C.M.7
Den Heijer, M.8
Rozen, R.9
Blom, H.J.10
-
29
-
-
0029895024
-
Elevated total plasma homocysteinemia and 677 C→T mutation of the 5,10-methylenetetrahydrofolate reductase gene in thrombotic vascular disease
-
letter
-
De Franchis R, Mancini FP, D'Angelo A, Sebastio G, Fermo I, De Stefano V, Margaglione M, Mazzola G, Di Minno G, Andria G: Elevated total plasma homocysteinemia and 677 C→T mutation of the 5,10-methylenetetrahydrofolate reductase gene in thrombotic vascular disease. Am J Hum Genet 59:264, 1996 (letter)
-
(1996)
Am J Hum Genet
, vol.59
, pp. 264
-
-
De Franchis, R.1
Mancini, F.P.2
D'Angelo, A.3
Sebastio, G.4
Fermo, I.5
De Stefano, V.6
Margaglione, M.7
Mazzola, G.8
Di Minno, G.9
Andria, G.10
-
30
-
-
0031202097
-
677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene in Northern Italy
-
letter
-
677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene in Northern Italy. Thromb Haemost 78:963, 1997 (letter)
-
(1997)
Thromb Haemost
, vol.78
, pp. 963
-
-
Sacchi, E.1
Tagliabue, L.2
Duca, F.3
Mannucci, P.M.4
-
31
-
-
0028090414
-
Genetic dissection of complex traits
-
Lander ES, Schork NJ: Genetic dissection of complex traits. Science 265:2037, 1994
-
(1994)
Science
, vol.265
, pp. 2037
-
-
Lander, E.S.1
Schork, N.J.2
-
32
-
-
0026034240
-
Thermolabile methylenetetrahydrofolate reductase: An inherited risk factor for coronary artery disease
-
Kang, S-S, Wong PWK, Susmano A, Sora H, Norusis M, Ruggie N: Thermolabile methylenetetrahydrofolate reductase: An inherited risk factor for coronary artery disease. Am J Hum Genet 48:536, 1991
-
(1991)
Am J Hum Genet
, vol.48
, pp. 536
-
-
Kang, S.-S.1
Wong, P.W.K.2
Susmano, A.3
Sora, H.4
Norusis, M.5
Ruggie, N.6
-
33
-
-
0029931750
-
Molecular genetic aspects of hyperhomocysteinemia and its relation to folic acid
-
Rozen R: Molecular genetic aspects of hyperhomocysteinemia and its relation to folic acid. Clin Invest Med 19:171, 1996
-
(1996)
Clin Invest Med
, vol.19
, pp. 171
-
-
Rozen, R.1
-
35
-
-
0029881624
-
More folic acid for everyone, now
-
Oakley GP Jr, Adams MJ, Dickinson CM: More folic acid for everyone, now. J Nutr 126:7515, 1996
-
(1996)
J Nutr
, vol.126
, pp. 7515
-
-
Oakley Jr., G.P.1
Adams, M.J.2
Dickinson, C.M.3
-
36
-
-
0029974036
-
Determinants and vitamin responsivness of intermediate hyperhomocysteinemia (≥40 μmol/liter). The Hordaland homocysteine study
-
Guttormsen AB, Ueland PM, Nesthus I, Nygård, O, Schneede J, Vollset SE, Refsum H: Determinants and vitamin responsivness of intermediate hyperhomocysteinemia (≥40 μmol/liter). The Hordaland homocysteine study. J Clin Invest 98:2174, 1996
-
(1996)
J Clin Invest
, vol.98
, pp. 2174
-
-
Guttormsen, A.B.1
Ueland, P.M.2
Nesthus, I.3
Nygård, O.4
Schneede, J.5
Vollset, S.E.6
Refsum, H.7
-
37
-
-
0030975769
-
The effects of folic acid supplementation on plasma total homocysteine are modulated by multivitamin use and methylenetetrahydrofolate reductase genotypes
-
Malinow MR, Nieto FJ, Kruger WD, Duell PB, Hess DL, Gluckman RA, Block PC, Holzgang CR, Andreson PH, Seltzer D, Upson B, Lin QR: The effects of folic acid supplementation on plasma total homocysteine are modulated by multivitamin use and methylenetetrahydrofolate reductase genotypes. Arterioscler Thromb Vase Biol 17:1157, 1997
-
(1997)
Arterioscler Thromb Vase Biol
, vol.17
, pp. 1157
-
-
Malinow, M.R.1
Nieto, F.J.2
Kruger, W.D.3
Duell, P.B.4
Hess, D.L.5
Gluckman, R.A.6
Block, P.C.7
Holzgang, C.R.8
Andreson, P.H.9
Seltzer, D.10
Upson, B.11
Lin, Q.R.12
-
38
-
-
0030955502
-
Thermolabile variant of the 5,10-methylenetetrahydrofolate reductase associated with low red-cell folates: Implications for folate intake and recommendations
-
Molloy AM, Daly S, Mills JL, Kirke PN, Whitehead AS, Ramsbottom D, Conley MR, Weir DG, Scott JM: Thermolabile variant of the 5,10-methylenetetrahydrofolate reductase associated with low red-cell folates: Implications for folate intake and recommendations. Lancet 349:1591, 1997
-
(1997)
Lancet
, vol.349
, pp. 1591
-
-
Molloy, A.M.1
Daly, S.2
Mills, J.L.3
Kirke, P.N.4
Whitehead, A.S.5
Ramsbottom, D.6
Conley, M.R.7
Weir, D.G.8
Scott, J.M.9
-
39
-
-
0028853921
-
Prevalence of moderate hyperhomocysteinemia in patients with early-onset venous and arterial occlusive disease
-
Fermo I, D'Angelo SV, Paroni R, Mazzola G, Calori G, D'Angelo A: Prevalence of moderate hyperhomocysteinemia in patients with early-onset venous and arterial occlusive disease. Ann Intern Med 123:747, 1995
-
(1995)
Ann Intern Med
, vol.123
, pp. 747
-
-
Fermo, I.1
D'Angelo, S.V.2
Paroni, R.3
Mazzola, G.4
Calori, G.5
D'Angelo, A.6
-
40
-
-
1842331509
-
Plasma homocysteine as a risk factor for vascular disease
-
The European Concerted Action Project: Graham IM, Daly LE, Retsum HM, Robinson K, Brattström LE, Ueland PM, Palma-Reis RJ, Boers GHJ, Sheahan RG, Israelsson B, Uiterwaal CS, Meleady R, McMaster D, Verhoef P, Witteman J, Rubba P, Bellet H, Wautrecht JC, de Valk HW, Sales Lúis AC, Parrot-Roulaud FM, Soon Tan K, Higgins I, Garcon D, Medrano MJ, Candito M, Evans AE. Andria G: Plasma homocysteine as a risk factor for vascular disease. JAMA 277:1775, 1997
-
(1997)
JAMA
, vol.277
, pp. 1775
-
-
Graham, I.M.1
Daly, L.E.2
Retsum, H.M.3
Robinson, K.4
Brattström, L.E.5
Ueland, P.M.6
Palma-Reis, R.J.7
Boers, G.H.J.8
Sheahan, R.G.9
Israelsson, B.10
Uiterwaal, C.S.11
Meleady, R.12
McMaster, D.13
Verhoef, P.14
Witteman, J.15
Rubba, P.16
Bellet, H.17
Wautrecht, J.C.18
De Valk, H.W.19
Sales Lúis, A.C.20
Parrot-Roulaud, F.M.21
Soon Tan, K.22
Higgins, I.23
Garcon, D.24
Medrano, M.J.25
Candito, M.26
Evans, A.E.27
Andria, G.28
more..
-
41
-
-
0028220787
-
Vitamin B-6 deficiency vs folate deficiency: Comparison of responses to methionine loading in rats
-
Miller JW, Nadeau MR, Smith D, Selhub J: Vitamin B-6 deficiency vs folate deficiency: Comparison of responses to methionine loading in rats. Am J Clin Nutr 59:1033, 1994
-
(1994)
Am J Clin Nutr
, vol.59
, pp. 1033
-
-
Miller, J.W.1
Nadeau, M.R.2
Smith, D.3
Selhub, J.4
|