Development of CRF1 receptor antagonists as antidepressants and anxiolytics: Progress to date

CNS Drugs

Volumn 20, Issue 11, 2006, Pages 887-896

  Valdez, Glenn R ^a  

^a GRAND VALLEY STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [8 (2,4 DICHLOROPHENYL) 2 METHYLQUINOLIN 4 YL] 1,2,6 TETRAHYDROPYRIDINE R CARBOXAMIDE BENZENESULFONIC ACID; 3 (6 DIMETHYLAMINO 4 METHYL 3 PYRIDINYL) 7 DIPROPYLAMINO 2,5 DIMETHYLPYRAZOLO[1,5 A]PYRIMIDINE; 4 (2 CHLORO 4 METHOXY 5 METHYLPHENYL N[(1S) 2 CYCLOPROPYL 1 (3 FLUORO 4 METHYLPHENYL)ETHYL]5 METHYL N(2 PROPYNYL) 1,3 THIAZOL 2 AMINE HYDROCHLORIDE; 4 [4 (3 FLUOROPHENYL) 1,2,3,6 TETRAHYDRO 1 PYRIDINYL] 2 [N ETHYL N (4 ISOPROPYL 2 METHYLTHIOPHENYL)AMINO] 6 METHYLPYRIMIDINE; 8 (2,4 DICHLOROPHENYL) 4 [2 METHOXY 1 (METHOXYMETHYL)ETHYLAMINO] 2,7 DIMETHYLPYRAZOLO[1,5 A][1,3,5]TRIAZINE; ALPRAZOLAM; ANTALARMIN; ANTIDEPRESSANT AGENT; ANTISAUVAGINE 30; ANXIOLYTIC AGENT; ASTRESSIN; BUTYL[2,5 DIMETHYL 7 (2,4,6 TRIMETHYLPHENYL) 7H PYRROLO[2,3 D]PYRIMIDIN 4 YL]ETHYLAMINE; CITALOPRAM; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; CRA 0450; DESIPRAMINE; DEXTRO PHENYLALANINE CORTICOTROPIN RELEASING FACTOR 12-41; DMP 904; FLUOXETINE; IMIPRAMINE; N(1 ETHYL PROPYL)[E(4 METHOXY 2 METHYLPHENYL) 2,5 DIMETHYLPYRAZOLO[1,5 A]PYRIMIDIN 7 YL]AMINE; NBI 3B1996; NORADRENALIN UPTAKE INHIBITOR; PAROXETINE; R 27899; REBOXETINE; SEROTONIN UPTAKE INHIBITOR; SSR 125543 A; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; CORTICOTROPIN RELEASING FACTOR RECEPTOR; CRF RECEPTOR TYPE 1; PYRIMIDINE DERIVATIVE;

ANXIETY DISORDER; AUTONOMIC NERVOUS SYSTEM; CLINICAL TRIAL; DEPRESSION; DIZZINESS; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SAFETY; HEADACHE; HUMAN; NAUSEA; NEUROENDOCRINE SYSTEM; NONHUMAN; PRIORITY JOURNAL; REVIEW; ANIMAL; ANXIETY; DRUG ANTAGONISM; MENTAL STRESS; PSYCHOLOGICAL ASPECT;

ANIMALS; ANTI-ANXIETY AGENTS; ANTIDEPRESSIVE AGENTS; ANXIETY; CLINICAL TRIALS; DEPRESSION; HUMANS; PYRIMIDINES; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; STRESS, PSYCHOLOGICAL;

EID: 33750266576     PISSN: 11727047     EISSN: 11727047     Source Type: Journal    
DOI: 10.2165/00023210-200620110-00002     Document Type: Review

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