Catechol O-methyltransferase Val158Met polymorphism is associated with cognitive performance in nondemented adults

Journal of Cognitive Neuroscience

Volumn 17, Issue 7, 2005, Pages 1018-1025

  De Frias, Cindy M ^a,b   Annerbrink, Kristina ^c   Westberg, Lars ^c   Eriksson, Elias ^c   Adolfsson, Rolf ^d   Nilsson, Lars Göran ^a,e  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

^d UMEÅ UNIVERSITY   (Sweden)

^e Det Norske Videnskaps Akademi   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL METHYLTRANSFERASE; DOPAMINE; METHIONINE; VALINE;

ADULT; AGED; ALLELE; ARTICLE; COGNITION; COMT GENE; CONTROLLED STUDY; DEPTH PERCEPTION; ENZYME ACTIVITY; GENE; GENE FUNCTION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN EXPERIMENT; INTELLIGENCE; MALE; MEMORY; NORMAL HUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; CATECHOL O-METHYLTRANSFERASE; COGNITION; FACTOR ANALYSIS, STATISTICAL; HUMANS; MALE; MEMORY, SHORT-TERM; METHIONINE; MIDDLE AGED; MOLECULAR BIOLOGY; NEUROPSYCHOLOGICAL TESTS; POLYMORPHISM, GENETIC; PROBLEM SOLVING; RETROSPECTIVE STUDIES; VALINE; VERBAL BEHAVIOR;

EID: 22944486039     PISSN: 0898929X     EISSN: None     Source Type: Journal    
DOI: 10.1162/0898929054475136     Document Type: Article

References (51)

1. Akil, M., Kolachana, B. S., Rothmond, D. A., Hyde, T. M., Weinberger, D. R., & Kleinman, J. E. (2003). Catechol-O-methyltransferase genotype and dopamine regulation in human brain. Journal of Neuroscience, 23, 2008-2013.
2. Anderson, S. W., & Tranel, D. (2002). Neuropsychological consequences of dysfunction in human dorsolateral prefrontal cortex. In J. Grafman (Ed.), Handbook of neuropsychology (Vol. 7, 2nd ed., pp. 145-156). New York: Elsevier.
3. Bäckman, L., & Farde, L. (2004). The role of dopamine systems in cognitive aging. In R. Cabeza, L. Nyberg, & D. C. Park (Eds.), Cognitive neuroscience of aging: Linking cognitive and cerebral aging (pp. 58-84). New York: Oxford University Press.
4. Bäckman, L., Ginovart, N., Dixon, R. A., Wahlin, T. B. R., Wahlin, A., Halldin, C., & Farde, L. (2000). Age-related cognitive deficits mediated by changes in the striatal dopamine system. American Journal of Psychiatry, 157, 635-637.
5. Baddeley, A., Lewis, V., Eldridge, M., & Thomson, N. (1984). Attention and retrieval from long-term memory. Journal of Experimental Psychology: General, 113, 518-540.
6. Bakes, P. B., Lindenberger, U., & Staudinger, U. M. (1998). Life-span theory in developmental psychology. In R. M. Lerner (Ed.), Theoretical models of human development: Handbook of child psychology (Vol. 1, 5th ed., pp. 1031-1082). New York: Wiley.
7. Baunez, C., & Robbins, T. W. (1999). Effects of dopamine depletion of the dorsal striatum and further interaction with subthalamic nucleus lesions in an attentional task in the rat. Neuroscience, 92, 1343-1356.
8. 158Met polymorphism in chronic schizophrenia. Biological Psychiatry, 52, 701-707.
9. Bilder, R. M., Volavka, J., Lachman, H. M., & Grace, A. A. (2004). The catechol-O-methyltranseferase polymorphism: Relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes. Neuropsychopharmacology, 1-19.
10. Cabeza, R., & Nyberg, L. (2000). Imaging cognition: II. An empirical review of 275 PET and fMRI studies. Journal of Cognitive Neuroscience, 12, 1-47.
11. Dagher, A., Owen, A. M., Boecker, H., & Brooks, D. J. (1999). Mapping the neural network for planning: A correlational PET activation study with the Tower of London task. Brain, 122, 1973-1987.
12. de Prias, C. M., Annerbrink, K., Westberg, L., Eriksson, E., Adolfsson, R., & Nilsson, L.-G. (2004). COMT gene polymorphism is associated with declarative memory in adulthood and old age. Behavior Genetics, 34, 533-539.
13. de Frias, C. M., Dixon, R. A., & Strauss, E. (2004). Structure of executive functioning tests in healthy older adults. Manuscript submitted for publication.
14. Diamond, A., Briand, L., Fossella, J., & Gehlbach, L. (2004). Genetic and neurochemical modulation of prefrontal cognitive functions in children. American Journal of Psychiatry, 161, 125-132.
15. Dreher, J. C., & Burnod, Y. (2002). An integrative theory of the phasic and tonic modes of dopamine modulation in the prefrontal cortex. Neural Networks, 15, 583-602.
16. Durstewitz, D., & Seamans, J. K. (2002). The computational role of dopamine D1 receptors in working memory. Neural Networks, 15, 561-572.
17. Egan, M. F., Goldberg, T. E., Kolachana, B. S., Callicott, J. H., Mazzanti, C. M., & Straub, R. E. (2001). Effect of COMT Val108/158Met genotype on frontal lobe function and risk for schizophrenia. Proceedings of the National Academy of Sciences, U.S.A., 98, 6917-6922.
18. 108/158Met) gene polymorphism with prefrontal P300 during information processing. Biological Psychiatry, 54, 40-48.
19. 158Met genotype and schizophrenia. Archives of General Psychiatry, 60, 889-896.
20. Iidaka, T., Anderson, N. D., Kapur, S., Cabeza, R., & Craik, F. I. M. (2000). The effect of divided attention on encoding and retrieval in episodic memory revealed by positron emission tomography. Journal of Cognitive Neuroscience, 12, 267-280.
21. Joober, R., Gauthier, J., Lal, S., Bloom, D., Lalonde, P., Rouleau, G., Benkelfat, C., & Labelle, A. (2002). Catechol-O-methyltransferase Val-108/158-Met gene variants associated with performance on the Wisconsin Card Sorting test. Archives of General Psychiatry, 59, 662-663.
22. Jöreskog, K. G., & Sörbom, D. (2000). LISREL 8 user's reference guide. Chicago: Scientific Software.
23. Kensinger, E. A., Clarke, R. J., & Corkin, S. (2003). What neural correlates underlie successful encoding and retrieval? A functional magnetic resonance imaging study using a divided attention paradigm. Journal of Neuroscience, 23, 2407-2415.
24. Lachman, H. M., Papolos, D. F., Saito, T., Yu, Y. M., Szumlanski, C. L., & Weinshilboum, R. M. (1996). Human catechol-O-methyltransferase pharmacogenetics: Description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics, 6, 243-250.
25. Lezak, M. D. (1995). Neuropsychological assessment (3rd ed.). New York: Oxford University Press.
26. Lotta, T., Vidgren, J., Tilgmann, C., Ulmanen, I., Melén, K., Julkunen, I., & Taskinen, J. (1995). Kinetics of human soluble and membrane-bound catechol O-methyltransferase: A revised mechanism and description of the thermolabile variant of the enzyme. Biochemistry, 34, 4202-4210.
27. Luciana, M., & Collins, P. F. (1997). Dopamine modulates working memory for spatial but not object cues in normal humans. Journal of Cognitive Neuroscience, 9, 330-347.
28. 2 dopamine receptor agonist. Journal of Cognitive Neuroscience, 4, 58-68.
29. Malhotra, A. K., Kestler, L. J., Mazzanti, C., Bates, J. A., Goldberg, T., & Goldman, D. (2002). A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition. American Journal of Psychiatry, 159, 652-654.
30. 158-met genotype and individual variation in the brain response to amphetamine. Proceedings of the National Academy of Sciences, U.S.A., 100, 6186-6191.
31. Meco, G., & Alessandri, A. (2000). Can COMT inhibitors improve cognitive functions in patients with Parkinson's disease? CNS Drugs, 13, 227-232.
32. Miyake, A., Emerson, M. J., & Friedman, N. P. (2000). Assessment of executive functions in clinical settings: Problems and recommendations. Seminars in Speech and Language, 21, 169-183.
33. Miyake, A., Friedman, N. P., Emerson, M. J., Witzki, A. H., & Howerter, A. (2000). The unity and diversity of executive functions and their contributions to complex "frontal lobe" tasks: A latent variable analysis. Cognitive Psychology, 41, 49-100.
34. Nieoullon, A. (2002). Dopamine and the regulation of cognition and attention. Progress in Neurobiology, 67, 53-83.
35. Nilsson, L.-G., Adolfsson, R., Bäckman L., de Prias, C. M., Nyberg, L., & Molander, B. (2004). Betula: A prospective study on memory, health, and aging. Aging, Neuropsychology, and Cognition, 11, 134-148.
36. Nilsson, L.-G., Bäckman, L., Erngrund, K., Nyberg, L., Adolfsson, R., Bucht, G., Karlsson, S., Widing, M., & Winblad, B. (1997). The Betula prospective cohort study: Memory, health, and aging. Aging, Neuropsychology, and Cognition, 4, 1-32.
37. 158Met polymorphism in schizophrenia: Differential effects of val and met alleles on cognitive stability and flexibility. American Journal of Psychiatry, 161, 359-361.
38. Nordfors, L., Jansson, M., Sandberg, G., Lavebratt, C., Sengul, S., Schalling, M., & Arner, P. (2002). Large-scale genotyping of single nucleotide polymorphisms by Pyrosequencing trademark and validation against the 5′ nuclease (Taqman (R)) assay. Human Mutation, 19, 395-401.
39. Phelps, E. A., Hyder, F., Blamire, A. M., & Shulman, R. G. (1997). fMRI of the prefrontal cortex during overt verbal fluency. NeuroReport, 8, 561-565.
40. Rabbitt, P. (1997). Introduction: Methodologies and models in the study of executive function. In P. Rabbitt (Ed.), Methodology of frontal and executive function (pp. 1-38). UK: Psychology Press.
41. Raz, N. (2004). The aging brain: Structural changes and their implications for cognitive aging. In R. A. Dixon, L. Bäckman, & L. G. Nilsson (Eds.), New frontiers in cognitive aging (pp. 115-133). New York: Oxford University Press.
42. Raz, N., Briggs, S. D., Marks, W., & Acker, J. D. (1999). Age-related deficits in generation and manipulation of mental images: II. The role of dorsolateral prefrontal cortex. Psychology and Aging, 14, 436-444.
43. Robbins, T. W., James, M., Owen, A. M., Sahakian, B. J., Lawrence, A. D., McInnes, L., & Rabbitt, P. (1998). A study of performance on tests from the CANTAB battery sensitive to frontal lobe dysfunction in a large sample of normal volunteers: Implications for theories of executive functioning and cognitive aging. Journal of the International Neuropsychological Society, 4, 474-490.
44. Rönnlund, M., Lövdén, M., & Nilsson, L.-G. (2001). Adult age differences in Tower of Hanoi performance: Influence from demographic and cognitive variables. Aging, Neuropsychology, and Cognition, 8, 269-283.
45. Salthouse, T. A., Atkinson, T. M., & Berish, D. E. (2003). Executive functioning as a potential mediator of age-related cognitive decline in normal adults. Journal of Experimental Psychology: General, 132, 566-594.
46. Tsai, S. J., Yu, Y. W., Chen, T. J., Chen, J. Y., Liou, Y. J., Chen, M. C., & Hong, C. J. (2003). Association study of a functional catechol-O-methyltransferase-gene polymorphism and cognitive function in healthy females. Neuroscience Letters, 338, 123-126.
47. Volkow, N. D., Gur, R. C., Wang, G.-J., Fowler, J. S., Moberg, P. J., Ding, Y.-S., Hitzemann, R., Smith, G., & Logan, J. (1998). Association between decline in brain dopamine activity with age and cognitive and motor impairment in healthy individuals. American Journal of Psychiatry, 155, 344-349.
48. 1 receptors in human brain: A PET study. Synapse, 30, 56-61.
49. Wechsler, D. (1991). Manual for the Wechsler Adult Intelligence Scale-Revised. New York: The Psychological Corporation.
50. Weinberger, D. R., Egan, M. F., Bertolino, A., Callicott, J. H., Mattay, V. S., Lipska, B. K., Berman, K. F., & Goldberg, T. E. (2001). Neurobiology of schizophrenia and the role of atypical antipsychotics: Prefrontal neurons and the genetics of schizophrenia. Biological Psychiatry, 50, 825-844.
51. Williams, G. V., & Goldman-Rakic, P. S. (1995). Modulation of memory fields by dopamine D1 receptors in prefrontal cortex. Nature, 376, 572-575.