Blockade of A2a adenosine receptors positively modulates turning behaviour and c-fos expression induced by D1 agonists in dopamine-denervated rats

European Journal of Neuroscience

Volumn 8, Issue 6, 1996, Pages 1176-1181

  Pinna, A ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

Basal ganglia; D1 receptors; Early genes; Parkinson's disease; Striatum

Indexed keywords

1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE; 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; 9 CHLORO 2 (2 FURYL) (1,2,4)TRIAZOLO(1,5 C)QUINAZOLIN 5 IMINE; 9-CHLORO-2-(2-FURYL)-(1,2,4)TRIAZOLO(1,5-C)QUINAZOLIN-5-IMINE; ADENOSINE RECEPTOR; DOPAMINE 1 RECEPTOR; NERVE PROTEIN; OXIDOPAMINE; PROTEIN C FOS; PYRIMIDINE DERIVATIVE; QUINAZOLINE DERIVATIVE; TRIAZOLE DERIVATIVE; XANTHINE DERIVATIVE; 9 CHLORO 2 (2 FURYL) 5,6 DIHYDRO 5 IMINO 1,2,4 TRIAZOLO[2,3 C]QUINAZOLINE; ADENOSINE; ADENOSINE A2 RECEPTOR; DOPAMINE; DOPAMINE 1 RECEPTOR STIMULATING AGENT;

ANIMAL; ARTICLE; BIOSYNTHESIS; DENERVATION; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; MALE; MOTOR ACTIVITY; RAT; ROTATION; SPRAGUE DAWLEY RAT; ANIMAL EXPERIMENT; ANIMAL MODEL; BEHAVIOR; CONTROLLED STUDY; CORPUS STRIATUM; GENE EXPRESSION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; ONCOGENE C FOS; PARKINSON DISEASE; PRIORITY JOURNAL; RECEPTOR BLOCKING;

2,3,4,5-TETRAHYDRO-7,8-DIHYDROXY-1-PHENYL-1H-3-BENZAZEPINE; ANIMALS; DENERVATION; MALE; MOTOR ACTIVITY; NERVE TISSUE PROTEINS; OXIDOPAMINE; PROTO-ONCOGENE PROTEINS C-FOS; PYRIMIDINES; QUINAZOLINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D1; RECEPTORS, PURINERGIC P1; ROTATION; TRIAZOLES; XANTHINES;

EID: 0029666492     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1996.tb01285.x     Document Type: Article

References (5)

1. Alexander, S. P. and Reddington, M. (1989) The cellular localization of adenosine receptors in rat neostriatum. Neuroscience, 28, 645-651.
2. Augood, S. J. and Emson, P. C. (1994) Adenosine A2a receptor mRNA is expressed by enkephalin cells but not by somatostatin cells in rat striatum. Mol. Brain Res., 22, 204-210.
3. Barone, P., Davis, T. A., Braun, A. R. and Chase, T. N. (1986) Dopaminergic mechanisms and motor function: characterization of D-l and D-2 dopamine receptor interactions. Eur. J. Pharmacol., 123, 109-114.
4. Braun, A. R. and Chase, T. N. (1986) Obligatory D-1/D-2 receptor interaction in the generation of dopamine agonist related behaviors. Eur. J. Pharmacol., 131, 301-306.
5. 2a purine receptors regulate striatal acetylcholine release. J. Neurochem., 55, 31-36.