Cyclooxygenase inhibition and atherothrombosis

Current Drug Targets

Volumn 7, Issue 10, 2006, Pages 1275-1284

  Sohn, Hae Young ^a   Krötz, Florian ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Aspirin; COX 2; CYP450; Lumiracoxib; NSAID

Indexed keywords

4 [5 (4 CHLOROPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOL 1 YL]BENZENESULFONAMIDE; ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; DICLOFENAC; ETORICOXIB; IBUPROFEN; INDOMETACIN; LUMIRACOXIB; NAPROXEN; NIMESULIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PARECOXIB; PLACEBO; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; ROFECOXIB; STREPTOKINASE; THROMBOXANE A2; VALDECOXIB; WARFARIN;

CARDIOVASCULAR DISEASE; CLINICAL TRIAL; DRUG HALF LIFE; DRUG POTENTIATION; DRUG TARGETING; DRUG WITHDRAWAL; ENZYME INHIBITION; GASTROINTESTINAL SYMPTOM; GASTROINTESTINAL TOXICITY; HEART INFARCTION; HUMAN; IN VIVO STUDY; INFLAMMATION; ISCHEMIC HEART DISEASE; LOW DRUG DOSE; META ANALYSIS; NONHUMAN; PAIN; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; REVIEW; RISK ASSESSMENT; SECONDARY PREVENTION; STROKE; SYSTEMATIC REVIEW; THROMBOCYTE AGGREGATION INHIBITION; THROMBOSIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ATHEROSCLEROSIS; CYCLOOXYGENASE INHIBITORS; HUMANS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES;

EID: 33749440081     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945006778559102     Document Type: Review

References (98)

1. Weiss, H. J., Aledort, L. M. and Kochwa, S. (1968) J. Clin. Invest. 47, 2169-2180.
2. Craven, L. L. (1953) Miss. Valley. Med. J. 75, 38-44.
3. Mukherjee, D. (2002) Biochem. Pharmacol. 63, 817-821.
4. Bing, R. J. and Lomnicka, M. (2002) J. Am. Coll. Cardiol. 39, 521-522.
5. Mukherjee, D., Nissen, S. E. and Topol, E. J. (2001) JAMA 286, 954959.
6. Rahme, E., Pilote, L. and LeLorier, J. (2002) Arch. Intern. Med. 162, 1111-1115.
7. Solomon, D. H., Glynn, R. J., Levin, R. and Avorn, J. (2002) Arch. Intern. Med. 162, 1099-1104.
8. Mukherjee, D., Nissen, S. E. and Topol, E. J. (2002) Arch. Intern. Med. 162, 2637-2639.
9. Shinohara, H., Balboa, M. A., Johnson, C. A., Balsinde, J. and Dennis, E. A. (1999) J. Biol. Chem. 274, 12263-12268.
10. Roman, R. J. (2002) Physiol. Rev. 82, 131-185.
11. Warner, T. D. and Mitchell, J. A. (2004) FASEB J. 18, 790-804.
12. Davidge, S. T. (2001) Circ. Res. 89, 650-660.
13. FitzGerald, G. A. (2003) Nat. Rev. Drug Discov. 2, 879-890.
14. Smith, W. L., DeWitt, D. L. and Garavito, R. M. (2000) Annu. Rev. Biochem. 69, 145-182.
15. Helliwell, R. J., Adams, L. F. and Mitchell, M. D. (2004) Prostaglandins Leukot. Essent. Fatty Acids 70, 101-113.
16. Picot, D., Loll, P. J. and Garavito, R. M. (1994) Nature 367, 243-249.
17. Landino, L. M., Crews, B. C., Gierse, J. K., Hauser, S. D. and Marnett, L. J. (1997) J. Biol. Chem. 272, 21565-21574.
18. Hinz, B. and Brune, K. (2002) J. Pharmacol. Exp. Ther. 300, 367-375.
19. Vane, J. R., Bakhle, Y. S. and Botting, R. M. (1998) Annu. Rev. Pharmacol. Toxicol. 38, 97-120.
20. Hinz, B., Brune, K. and Pahl, A. (2000) Biochem. Biophys. Res. Commun. 278, 790-796,
21. Chandrasekharan, N. V., Dai, H., Roos, K. L., Evanson, N. K., Tomsik, J., Elton, T. S. and Simmons, D. L. (2002) Proc. Natl. Acad. Sci. USA 99, 13926-13931.
22. Schwab, J. M., Schluesener, H. J. and Laufer, S. (2003) Lancet 361, 981-982.
23. FitzGerald, G. A. (1991) Am. J. Cardiol. 68, 11B-15B.
24. Liou, J. Y., Shyue, S. K., Tsai, M. J., Chung, C. L., Chu, K. Y. and Wu, K. K. (2000) J. Biol. Chem. 275, 15314-15320.
25. Camacho, M., Lopez-Belmonte, J. and Vila, L. (1998) Circ. Res. 83, 353-365.
26. Wright, D. H., Abran, D., Bhattacharya, M., Hou, X., Bernier, S. G., Bouayad, A., Fouron, J. C., Vazquez-Tello, A., Beauchamp, M. H., Clyman, R. I., Peri, K., Varma, D. R. and Chemtob, S. (2001) Am. J. Physiol. Regul. Integr. Comp. Physiol. 281, R1343-R1360.
27. Loll, P. J., Picot, D. and Garavito, R. M. (1995) Nat. Struct. Biol. 2, 637-643.
28. Cipollone, F., Patrignani, P., Greco, A., Panara, M. R., Padovano, R., Cuccurullo, F., Patrono, C., Rebuzzi, A. G., Liuzzo, G., Quaranta, G. and Maseri, A. (1997) Circulation 96, 1109-1116.
29. Demers, L. M., Budin, R E. and Shaikh, B. S. (1980) Proc. Soc. Exp. Biol. Med. 163, 24-29.
30. Patrono, C., Coller, B., Dalen, J. E., FitzGerald, G. A., Fuster, V., Gent, M., Hirsh, J. and Roth, G. (2001) Chest 119, 39S-63S.
31. Antiplatelet Trialists' Collaboration (1994) BMJ 308, 81-106.
32. Patrignani, P., Filabozzi, P. and Patrono, C. (1982) J. Clin. Invest. 69, 1366-1372.
33. Husain, S., Andrews, N. P., Mulcahy, D., Panza, J. A. and Quyyumi, A. A. (1998) Circulation 97, 716-720.
34. Steer, K. A., Wallace, T. M., Bolton, C. H. and Hartog, M. (1997) Heart 77, 333-337.
35. Awtry, E. H. and Loscalzo, J. (2000) Circulation 101, 1206-1218.
36. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. (1988) Lancet 2, 349-360.
37. Roux, S., Christeller, S. and Ludin, E. (1992) J. Am. Coll. Cardiol. 19, 671-677.
38. Nyman, I., Larsson, H. and Wallentin, L. (1992) Lancet 340, 497-501.
39. Wallentin, L. C. (1991) J. Am. Coll. Cardiol. 18, 1587-1593.
40. Various authors (2002) BMJ 324, 71-86.
41. Physician's health Study (1989) N. Engl. J. Med. 321, 1825-1928.
42. Peto, R., Gray, R., Collins, R., Wheatley, K., Hennekens, C., Jamrozik, K., Warlow, C., Hafner, B., Thompson, E., Norton, S. and. (1988) Br. Med. J. (Clin. Res. Ed.) 296, 313-316.
43. The Medical Research Council's General Practice Research Framework. (1998) Lancet 351, 233-241.
44. Ridker, P. M., Cook, N. R., Lee, I. M., Gordon, D., Gaziano, J. M., Manson, J. E., Hennekens, C. H. and Buring, J. E. (2005) N. Engl. J. Med. 352, 1293-1304.
45. Manson, J. E., Stampfer, M. J., Colditz, G. A., Willett, W. C., Rosner, B., Speizer, F. E. and Hennekens, C. H. (1991) JAMA 266, 521-527.
46. Baum, C., Kennedy, D. L. and Forbes, M. B. (1985) Arthritis Rheum. 28, 686-692.
47. FitzGerald, G. A. (2002) Am. J. Cardiol. 89, 26D-32D.
48. Malkowski, M. G., Ginell, S. L., Smith, W. L. and Garavito, R. M. (2000) Science 289, 1933-1937.
49. Leese, P. T., Hubbard, R. C., Karim, A., Isakson, P. C., Yu, S. S. and Geis, G. S. (2000) J. Clin. Pharmacol. 40, 124-132.
50. Patrono, C., Patrignani, P. and Garcia Rodriguez, L. A. (2001) J. Clin. Invest. 108, 7-13.
51. Crofford, L. J., Oates, J. C., McCune, W. J., Gupta, S., Kaplan, M. J., Catella-Lawson, F., Morrow, J. D., McDonagh, K. T. and Schmaier, A. H. (2000) Arthritis Rheum. 43, 1891-1896.
52. Capone, M. L., Tacconelli, S., Sciulli, M. G., Grana, M., Ricciotti, E., Minuz, P., Di Gregorio, P., Merciaro, G., Patrono, C. and Patrignani, P. (2004) Circulation 109, 1468-1471.
53. Knijff-Dutmer, E. A., Kalsbeek-Batenburg, E. M., Koerts, J. and van de Laar, M. A. (2002) Rheumatology. (Oxford) 41, 458-461.
54. Rinder, H. M., Tracey, J. B., Souhrada, M., Wang, C., Gagnier, R. P. and Wood, C. C. (2002) J. Clin. Pharmacol. 42, 881-886.
55. Kimmel, S. E., Berlin, J. A., Reilly, M., Jaskowiak, J., Kishel, L., Chittams, J. and Strom, B. L. (2004) J. Am. Coll. Cardiol. 43, 985-990.
56. Mamdani, M., Rochon, P., Juurlink, D. N., Anderson, G. M., Kopp, A., Naglie, G., Austin, P. C. and Laupacis, A. (2003) Arch. Intern. Med. 163, 481-486.
57. Ray, W. A., Stein, C. M., Hall, K., Daugherty, J. R. and Griffin, M. R. (2002) Lancet 359, 118-123.
58. Graham, D. J., Campen, D., Hui, R., Scence, M., Cheetham, C., Levy, G., Shoot, S. and Ray, W. A. (2005) Lancet 365, 475-481.
59. Knijff-Dutmer, E. A., Schut, G. A. and van de Laar, M. A. (2003) Ann. Pharmacother. 37, 12-16.
60. Schulman, S. and Henriksson, K. (1989) Br. J. Rheumatol. 28, 46-49.
61. Catella-Lawson, F., Reilly, M. P., Kapoor, S. C., Cucchiara, A. J., DeMarco, S., Tournier, B., Vyas, S. N. and FitzGerald, G. A. (2001) N. Engl. J. Med. 345, 1809-1817.
62. FitzGerald, G. A. (2003) Lancet 361, 542-544.
63. MacDonald, T. M. and Wei, L. (2003) Lancet 361, 573-574.
64. Buerkle, M. A., Lehrer, S., Sohn, H. Y., Conzen, P., Pohl, U. and Krotz, F. (2004) Circulation 110, 2053-2059.
65. Hennan, J. K., Huang, J., Barrett, T. D., Driscoll, E. M., Willens, D. E., Park, A. M., Crofford, L. J. and Lucchesi, B. R. (2001) Circulation 104, 820-825.
66. Bombardier, C., Laine, L., Reicin, A., Shapiro, D., Burgos-Vargas, R., Davis, B., Day, R., Ferraz, M. B., Hawkey, C. J., Hochberg, M. C., Kvien, T. K. and Schnitzer, T. J. (2000) N. Engl. J. Med. 343, 1520-8, 2.
67. Garcia Rodriguez, L. A., Varas-Lorenzo, C., Maguire, A. and Gonzalez-Perez, A. (2004) Circulation 109, 3000-3006.
68. Konstam, M. A., Weir, M. R., Reicin, A., Shapiro, D., Sperling, R. S., Barr, E. and Gertz, B. J. (2001) Circulation 104, 2280-2288.
69. Juni, P., Nartey, L., Reichenbach, S., Sterchi, R., Dieppe, P. A. and Egger, M. (2004) Lancet 364, 2021-2029.
70. Solomon, D. H., Schneeweiss, S., Glynn, R. J., Kiyota, Y., Levin, R., Mogun, H. and Avorn, J. (2004) Circulation 109, 2068-2073.
71. White, W. B., Faich, G., Borer, J. S. and Makuch, R. W. (2003) Am. J. Cardiol. 92, 411-418.
72. European Medicines Agency (2004) EMEA/214027/2004.
73. Moore, R. A., Derry, S., Makinson, G. T. and McQuay, H. J. (2005) Arthritis Res. Ther. 7, R644-R665.
74. Johnsen, S. P., Larsson, H., Tarone, R. E., McLaughlin, J. K., Norgard, B., Friis, S. and Sorensen, H. T. (2005) Arch. Intern. Med. 165, 978-984.
75. McAdam, B. F., Catella-Lawson, F., Mardini, I. A., Kapoor, S., Lawson, J. A. and FitzGerald, G. A. (1999) Proc. Natl. Acad. Sci. USA 96, 272-277.
76. White, W. B., Strand, V., Roberts, R. and Whelton, A. (2004) Am. J. Ther. 11, 244-250.
77. Ott, E., Nussmeier, N. A., Duke, P. C., Feneck, R. O., Alston, R. P., Snabes, M. C., Hubbard, R. C., Hsu, P. H., Saidman, L. J. and Mangano, D. T. (2003) J. Thorac. Cardiovasc. Surg. 125, 1481-1492.
78. Nussmeier, N. A., Whelton, A. A., Brown, M. T., Langford, R. M., Hoeft A., Parlow, J. L., Boyce, S. W. and Verburg, K. M. (2005) N. Engl. J. Med. 352, 1081-91.
79. Farkouh, M. E., Kirshner, H., Harrington, R. A., Ruland, S., Verheugt, F. W., Schnitzer, T. J., Burmester, G. R., Mysler, E., Hochberg, M. C., Doherty, M., Ehrsam, E., Gitton, X., Krammer, G., Mellein, B., Gimona, A., Matchaba, P., Hawkey, C. J. and Chesebro, J. H. (2004) Lancet 364, 675-684.
80. Hunt, R. H., Harper, S., Watson, D. J., Yu, C., Quan, H., Lee, M., Evans, J. K. and Oxenius, B. (2003) Am. J. Gastroenterol. 98, 1725-1733.
81. Pallay, R. M., Seger, W., Adler, J. L., Ettlinger, R. E., Quaidoo, E. A., Lipetz, R., O'Brien, K., Mucciola, L., Skalky, C. S., Petruschke, R. A., Bohidar, N. R. and Geba, G. P. (2004) Scand. J. Rheumatol. 33, 257-266.
82. Catella-Lawson, F., McAdam, B., Morrison, B. W., Kapoor, S., Kujubu, D., Antes, L., Lasseter, K. C., Quan, H., Gertz, B. J. and FitzGerald, G. A. (1999) J. Pharmacol. Exp. Ther. 289, 735-741.
83. Kearney, D., Byrne, A., Crean, P., Cox, D. and Fitzgerald, D. J. (2004) J. Am. Coll. Cardiol. 43, 526-531.
84. Belton, O. A., Duffy, A., Toomey, S. and Fitzgerald, D. J. (2003) Circulation 108, 3017-3023.
85. a) Belton, O., Byrne, D., Kearney, D., Leahy, A. and Fitzgerald, D. J. (2000) Circulation 102, 840-845.
86. b) Camacho, M., Lopez-Belmonte, J. and Vila, L. (1998) Circ. Res. 83, 353-365.
87. Qi, Z., Hao, C. M., Langenbach, R. I, Breyer, R. M., Redha, R., Morrow, J. D. and Breyer, M. D. (2002) J. Clin. Invest. 110, 61-69.
88. McAdam, B. F., Mardini, I. A., Habib, A., Burke, A., Lawson, J. A., Kapoor, S. and Fitzgerald, G. A. (2000) J. Clin. Invest. 105, 1473-1482.
89. Pidgeon, G. P., Tamosiuniene, R., Chen, G., Leonard, I., Belton, O., Bradford, A. and Fitzgerald, D. J. (2004) Circulation 110, 2701-2707.
90. Burleigh, M. E., Babaev, V. R., Oates, J. A., Harris, R. C., Gautam, S., Riendesu, D., Marnett, L. J., Morrow, J. D., Fazio, S. and Linton, M. F. (2002) Circulation 105, 1816-1823.
91. Widlansky, M. E., Price, D. T., Gokce, N., Eberhardt, R. T., Duffy, S. J., Holbrook, M., Maxwell, C., Palmisano, J., Keaney, J. F., Jr., Morrow, J. D. and Vita, J. A. (2003) Hypertension 42, 310-315.
92. Llinas, M. T., Lopez, R., Rodriguez, F., Roig, F. and Salazar, F. J. (2001) Am. J. Physiol. Renal. Physiol. 281, F975-F982.
93. Cheng, Y., Austin, S. C., Rocca, B., Koller, B. H., Coffman, T. M., Grosser, T., Lawson, J. A. and Fitzgerald, G. A. (2002) Science 296, 539-541.
94. Linton, M. F. and Fazio, S. (2004) Curr. Opin. Pharmacol. 4, 116-123.
95. Bogaty, P., Brophy, J. M., Noel, M., Boyer, L., Simard, S., Bertrand, F. and Dagenais, G. R. (2004) Circulation 110, 934-939.
96. Chenevard, R., Hurlimann, D., Bechir, M., Enseleit, F., Spieker, L., Hermann, M., Riesen, W., Gay, S., Gay, R. E., Neidhart, M., Michel, B., Luscher, T. F., Noll, G. and Ruschitzka, F. (2003) Circulation 107, 405-409.
97. LeLorier, J., Bombardier, C., Burgess, E., Moist, L., Wright, N., Cartier, P., Huckell, V., Hunt, R., Nawar, T. and Tobe, S. (2002) Can. J. Cardiol. 18, 1301-1308.
98. Sandhu, G. K. and Heyneman, C. A. (2004) Ann. Pharmacother. 38, 700-704.