Prenatal exposure to stress and stress hormones influences child development

Infants and Young Children

Volumn 19, Issue 3, 2006, Pages 246-259

  Davis, Elysia Poggi ^a,b   Sandman, Curt A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cortisol; Development; Pregnancy; Stress

Indexed keywords

EID: 33749413495     PISSN: 08963746     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001163-200607000-00008     Document Type: Article

References (128)

1. Abernethy, L. J., Cooke, R. W. I., & Foulder-Hughes, L. (2004). Caudate and hippocampal volumes, intelligence and motor impairment in 7-year-old children who were born preterm. Pediatric Research, 55(5), 884-893.
2. Albiston, A. L., Obeyesekere, V. R., Smith, R. E., & Krozowski, Z. S. (1994). Cloning and tissue distribution of the human 11β-hydroxysteroid dehydrogenase type 2 enzyme. Molecular and Cellular Endocrinology, 105(2), R11-R17.
3. Antonow-Schlorke, I., Kühn, B., Muller, T., Schubert, H., Sliwka, U., Nathanielsz, P. W., et al. (2001). Antenatal betamethasone treatment reduces synaptophysin immunoreactivity in presynaptic terminals in the fetal sheep brain. Neuroscience Letters, 297(3), 147-150.
4. Antonow-Schlorke, I., Schwab, M., Li, C., & Nathanielsz, P. W. (2003). Glucocorticoid exposure at the dose used clinically alters cytoskeletal proteins and presynaptic terminals in the fetal baboon brain. Journal of Physiology, 547(1), 117-123.
5. Arad, I., Durkin, M. S., Hinton, V. J., Kuhn, L., Chiriboga, C., Kuban, K., et al. (2002). Long-term cognitive benefits of antenatal corticosteroids for prematurely born children with cranial ultrasound abnormalities. American Journal of Endocrinal Metabolism, 186(4), 818-825.
6. Bakker, J. M., van Bel, E, & Heijnen, C. J. (2001). Neonatal glucocorticoids and the developing brain: Short term-treatment with life long consequences? Trends in Neuroscience, 24(11), 649-653.
7. Ballard, P. L., & Ballard, R. A. (1995). Scientific basis and therapeutic regimens for use of antenatal glucocorticoids. American Journal of Obstetrics & Gynecology, 173, 254-262.
8. Ballard, P. L., Gluckman, P. D., Liggens, G. C., Kaplan, S. L., & Grumbach, M. M. (1980). Steroid and growth hormone levels in premature infants after prenatal betamethasone therapy to prevent respiratory distress syndrome. Pediatric Research, 14(2), 122-127.
9. Barker, D. J. (1998). In utero programming of chronic disease. Clinical Science, 95(2), 115-128.
10. Bender, B. J., Lerner, J. A., & Kollasch, E. (1988). Mood and memory changes in asthmatic children receiving corticosteroids. American Academy of Child and Adolescent Psychiatry, 27(6), 720-725.
11. Benediktsson, R., Lindsay, R., Noble, J., Seckl, J. R., & Edwards, C. R. W. (1993). Glucocorticoid exposure In utero: A new model for adult hypertension. The Lancet, 341, 339-341.
12. Bloom, S. L., Sheffield, J. S., McIntire, D. D., & Leveno, K.J. (2001). Antenatal dexamethasone and decreased birth weight. Obstetrics & Gynecology, 97(4), 485-490.
13. Brabham, T., Phelka, A., Zimmer, C., Nash, A., Lopez, J. F., & Vazquez, D. (2000). Effects of prenatal dexamethasone on spatial learning and response to stress Is Influenced by maternal factors. American Journal of Physiology, Regulatory, Integrative, Comparative, and Physiology, 279, R1899-R1909.
14. Brouwers, E. P. M., van Baar, A. L., & Pop, V. J. M. (2001). Maternal anxiety during pregnancy and subsequent Infant development. Infant Behavior & Development, 24, 95-106.
15. Brown, R. W., Kotolevtsev, Y., Leckie, C., Lindsay, R. S., Lyons, V., Murad, P., et al. (1996). Isolation and cloning of human placental 11ß-hydroxysteroid dehydrogenase-2 cDNA. Biochemical Journal, 313, 1007-1017.
16. Buitelaar, J. K., Huizink, A. C., Mulder, E. J., de Medina, P. G., & Visser, G. H. (2003). Prenatal stress and cognitive development and temperament in infants. Neurobiology of Aging, 24(Suppl. 1), S53-S60; discussion S67-S58.
17. Butler, T. G., Schwartz, J., & McMillen, I. C. (2002). Differential effects of the early and late intrauterine environment on corticotrophic cell development. The Journal of Clinical Investigation, 110(6), 783-791.
18. Carmichael, S. L., & Shaw, G. M. (2000). Maternal life event stress and congenital anomalies. Epidemiology, 11(1), 30-35.
19. Challis, J. R., Sloboda, D., Matthews, S. G., Holloway, A., Alfaidy, N., Patel, F. A., et al. (2001). The fetal placental hypothalamic-pituitary-adrenal (HPA) axis, parturition and postnatal health. Molecular and Cellular Endocrinology, 185(1-2), 135-144.
20. Chapillon, P., Patin, V., Roy, V., Vincent, A., & Caston, J. (2002). Effects of pre- and postnatal stimulation on developmental, emotional, and cognitive aspects in rodents: A review. Developmental Psychobiology, 41, 373-387.
21. Chrousos, G. P., & Gold, P. W. (1992). The concept of stress and stress system disorders. Journal of the American. Medical Association, 267(9), 1244-1252.
22. Coe, C. L., Lulbach, G. R., & Schneider, M. L. (2002). Prenatal disturbance alters the size of the corpus callosum in young monkeys. Developmental Psychobiology, 41(2), 178-185.
23. Collaborative Group on Antenatal Steroid Therapy. (1984). Effects of antenatal dexamethasone administration in the infant: Long-term follow-up. Journal of Pediatrics, 104, 259-267.
24. Copper, R. L., Goldenberg, R. L., Elder, N., Swain, M., Norman, G., Ramsey, R., et al. (1996). The preterm prediction study: Maternal stress is associated with spontaneous preterm birth at less than thirty-five weeks' gestation. American Journal of Obstetrics & Gynecology, 175, 1286-1292.
25. Crowley, P (2000). Prophylactic corticosteroids for preterm birth. Cochrane Database of Systematic Reviews, issue 2, CD000065.
26. Davis, E. P., Snidman, N., Wadhwa, P D., Dunkel Schetter, C., Glynn, L., & Sandman, C. A. (2004). Prenatal maternal anxiety and depression predict negative behavioral reactivity in infancy. Infancy, 6(3), 319- 331.
27. Davis, E. P., Townsend, E. L., Gunnar, M. R., Georgieff, M. K., Guiang, S. F., Cifuentes, R. F., et al. (2004). Effects of prenatal corticosteroid exposure on regulation of stress physiology in healthy premature infants. Psychoneuroendocrinology, 29, 1028-1036.
28. Davis, E. P., Glynn, L. M., Dunkel Schetter, C., Hobel, C., Chicz-Demet, A., & Sandman, C. A. (2005). Corticotropin-releasing hormone during pregnancy is associated with infant temperament. Developmental Neuroscience, 27, 299-305.
29. de Kloet, R., Vreugdenhil, E., Oitzl, M. S., & Joels, A. (1998). Brain corticosteroid receptor balance in health and disease. Endocrine Reviews, 19(3), 269- 301.
30. de Quervain, D. J., Roozendaal, B., & McGaugh, J. L. (1998). Stress and glucocorticoids impair retrieval of long-term spatial memory. Nature, 394(6695), 787-790.
31. de Weerth, C., van Hees, Y., & Buitelaar, J. (2003). Prenatal maternal cortisol levels and Infant behavior during the first 5 months. Early Human Development, 74, 139-151.
32. Dessens, A. B., Smolders-de Haas, H., & Koppe, J. G. (2000). Twenty-year follow-up of antenatal corticosteroid treatment. Pediatrics, 105(6), 77-84.
33. Diorio, D., Viau, V., & Meaney, M. J. (1993). The role of the medial prefrontal cortex (cingulate gyrus) in the regulation of hypothalamic-pituitary- adrenal responses to stress. The Journal of Neuroscience, 13(9), 3839-3847.
34. DiPietro, J. A., Hilton, S. C., Hawkins, M., Costigan, K. A., & Pressman, E. K. (2002). Maternal stress and affect influence fetal neurobehavioral development. Developmental Psychology, 38(5), 659-668.
35. Dodic, M., May, C. N., Wintour, E. M., & Coghlan, J. P. (1998). An early prenatal exposure to excess glucocorticoid leads to hypertensive offspring in sheep. Clinical Science, 94, 149-155.
36. Dole, N., Savitz, D. A., Hertz-Picciotto, I., Siega-Riz, A. M., McMahon, M. J., & Buekens, P (2003). Maternal stress and preterm birth. American Journal of Epidemiology, 157, 14-24.
37. Dorr, H. G., Heller, A., Versmold, H. T., Sippell, W. G., Herrmann, M., Bidlingmaier, F., et al. (1989). Longitudinal study of progestins, mineralocorticoids, and glucocorticoids throughout human pregnancy. Journal of Clinical Endocrinology and Metabolism, 68(5), 863-868.
38. Doyle, L. W., Ford, G. W, Davis, N. M., & Callanan, C. (2000). Antenatal corticosteroid therapy and blood pressure at 14 years of age in preterm children. Clinical Science, 98, 137-142.
39. Doyle, L. W., Ford, G. W., Rickards, A. L., Kelly, E. A., Davis, N. M., Callanan, C., et al. (2000). Antenatal corticosteroids and outcome at 14 years of age in children with birth weight less than 1501 grams. Pediatrics, 106(1), E2.
40. Erickson, K., Thorsen, P., Chrousos, G., Grigoriadis, D. E., Khongsaly, O., McGregor, J., et al. (2001). Preterm birth: Associated neuroendocrine, medical and behavioral risk factors. Journal of Clinical Endocrinology and Metabolism, 86(6), 2544-2552.
41. Feldman, P. J., Dunkel-Schetter, C., Sandman, C. A., & Wadhwa, P. D. (2000). Maternal social support predicts birth weight and fetal growth in human pregnancy. Psychosomatic Medicine, 62(5), 715-725.
42. French, N., Hagan, R., Evans, S. F., Godfrey, M., & Newnham, J. (1999). Repeated antenatal corticosteroids: Size at birth and subsequent development. American Journal of Obstetrics & Gynecology, 180, 114-121.
43. Gluckman, P D., & Hanson, M. A. (2004). Living with the past: Evolution, development, and patterns of disease. Science, 305(5691), 1733-1736.
44. Glynn, L., Wadhwa, P. D., Dunkel-Schetter, C., & Sandman, C. A. (2001). When stress happens matters: Effects of earthquake timing on stress responsivity in pregnancy. American Journal of Obstetrics & Gynecology, 184(4), 637-642.
45. Godfrey, K. M., & Barker, D. J. (2000). Fetal nutrition and adult disease. American Journal of Clinical Nutrition, 71(5 Suppl.), 1344S-1352S.
46. Hansen, D., Lou, H. C., & Olsen, J. (2000). Serious life events and congenital malformations: A national study. The Lancet, 356, 875-880.
47. Hasbargen, U., Reber, D., Versmold, H., & Schulze, A. (2001). Growth and development of children to 4 years of age after repeated antenatal steroid administration. European Journal of Pediatrics, 160(9), 552-555.
48. Hedegaard, M., Henriksen, T. B., Secher, N. J., Hatch, M. C., & Sabroe, S. (1996). Do stressful life events affect duration of gestation and risk of preterm delivery? Epidemiology, 7, 339-345.
49. Hillhouse, E. W., & Grammatopoulos, D. K. (2002). Role of stress peptides during human pregnancy and labour. Reproduction, 124(3), 323-239.
50. Hobel, C. J., Dunkel-Schetter, C., Roesch, S. C., Castro, L.C., & Arora, C. P. (1999). Maternal plasma corticotropin-releasing hormone associated with stress at 20 weeks' gestation in pregnancies ending in preterm delivery. American Journal of Obstetrics & Gynecology, 180(1 Pt 3), S257-S263.
51. Holzman, C., Jetton, J., Siler-Khodr, T., Fisher, R., & Rip, T. (2001). Second trimester corticotropin-releasing hormone levels in relation to preterm delivery and ethnicity. Obstetrics & Gynecology, 97, 657-663.
52. Huang, W. L., Beazley, L. D., Quinlivan, J. A., Evans, S. F., Newnham, J. P., & Dunlop, S. A. (1999). Effect of corticosterolds on brain growth in fetal sheep. Obstetrics & Gynecology, 94, 213-218.
53. Huizink, A. C., de Medina, P. G., Mulder, E. J., Visser, G. H., & Buitelaar, J. K. (2002). Psychological measures of prenatal stress as predictors of infant temperament. Journal of the American Academy of Child and Adolescent Psychiatry, 41(9), 1078-1085.
54. Ikegami, M., Jobe, A. B., Newnham, J., Polk, D. H., Willet, K. E., & Sly, P. (1997). Repetitive prenatal gluco-corticoids improve lung function and decrease growth in pre-term lambs. American Journal of Respiratory and Critical Care Medicine, 156, 178-184.
55. Inder, W. J., Prickett, T. C., Ellis, M. J., Hull, L., Reid, R., Benny, P. S., et al. (2001). The utility of plasma CRH as a predictor of preterm delivery. Journal of Clinical Endocrinology and Metabolism, 86(12), 5706-5710.
56. Jacobson, L., & Sapolsky, R. (1991). The role of the hippocampus In feedback regulation of the hypothalamic pituitary adrenocortical axis. The Endocrine Reviews, 12(2), 118-134.
57. Jones, N. A., Field, T., Fox, N. A., Davalos, M., Lundy, B., & Hart, S. (1998). Newborns of mothers with depressive symptoms are physiologically less developed. Infant Behavior & Development, 27(3), 537-541.
58. Kajantie, E., Dunkel, L., Turpeinen, U., Stenman, U. H., Wood, P. J., Nuuttia, M., et al. (2003). Placental 11 beta-hydroxysteroid dehydrogenase-2 and fetal cortisol/cortisone shuttle in small preterm infants. Journal of Clinical Endocrinology and Metabolism, 88(1), 493-500.
59. Kauppila, A., Koivisto, M., Pukka, M., & Tuimala, R. (1978). Umbilical cord and neonatal cortisol levels. Effect of gestational and neonatal factors. Obstetrics & Gynecology, 52(6), 666-672.
60. King, B. R., Nicholson, R. C., & Smith, R. (2001). Placental corticotrophin-releasing hormone, local effects and fetomaternal endocrinology. Stress, 4, 219-233.
61. King, B. R., Smith, R., & Nicholson, R. C. (2001). The regulation of human corticotrophin-releasing hormone gene expression in the placenta. Peptides, 22(11), 1941-1947.
62. Korte, C., Styne, D., Merritt, A. T., Mayes, D., Wertz, A., & Helbock, H. J. (1996). Adrenocortical function in the very low birth weight infants: Improved testing for sensitivity and association with neonatal outcome. The Journal of Pediatrics, 128(2), 257-263.
63. Laplante, D. P., Barr, R. G., Brunet, A., Du Fort, G. G., Meaney, M. J., Saucier, J. F., et al. (2004). Stress during pregnancy affects general intellectual and language functioning in human toddlers. Pediatric Research, 56(3), 400-410.
64. Lobel, M. (1994). Conceptualizations, measurement, and effects of prenatal maternal stress on birth outcomes. Journal of Behavioral Medicine, 17(3), 225-271.
65. Lundy, B. L., Jones, N. A., Field, T., Nearing, G., Davalos, M., Pietro, P. A., et al. (1999). Prenatal depression effects on neonates. Infant Behavior & Development, 22(1), 119-129.
66. Luoma, I., Tamminen, T., Kaukonen, P., Laippala, P., Puura, K., Salmelin, R., et al. (2001). Longitudinal study of maternal depressive symptoms and child well-being. Journal of the American Academy of Child and Adolescent Psychiatry, 40(12), 1367-1374.
67. Lupien, S. J., Gillin, C. J., & Hauger, R. L. (1999). Working memory Is more sensitive than declarative memory to the acute effects of corticosteroids: A dose-response study in humans. Behavioral Neuroscience, 113(3), 420-430.
68. Lupien, S. J., Wilkinson, C. W, Briere, S., Ng Ying Kin, N. M. K., Meaney, M. J., & Nair, N. P. V. (2002). Acute modulation of a aged human memory by pharmacological manipulation of glucocorticoids. The Journal of Clinical Endocrinology and Metabolism, 87(8), 3798-3807.
69. Lyons, D. M., Lopez, J. M., Yang, C., & Schatzberg, A. F. (2000). Stress-level cortisol treatment impairs inhibitory control of behavior in monkeys. The Journal of Neuroscience, 20(20), 7816-7821.
70. MacArthur, B. A., Howie, R. N., Dezoete, J. A., & Elkins, J. (1982). School progress and cognitive development of 6-year-old children whose mothers were treated antenatally with betamethasone. Pediatrics, 70, 99-105.
71. Martin, R. P., Noyes, J., Wisenbaker, J., & Huttunen, M. O. (1999). Prediction of early childhood negative emotionality and inhibition from maternal distress during pregnancy. Merrill-Palmer Quarterly, 45(3), 370-391.
72. Matthews, S. G. (2000). Antenatal glucocorticoids and programming of the developing CNS. Pediatric Research, 47(3), 291-300.
73. McEwen, B. (1988). Stress, adaptation, and disease: Allostasis and allostatic load. Annals of the New York Academy of Science, 840, 33-44.
74. McLean, M., Bisits, A., Davies, J., Woods, R., Lowry, P., & Smith, R. (1995). A placental clock controlling the length of human pregnancy. Nature Medicine, 1, 460-463.
75. Meaney, M. J., Diorio, J., Francis, D., Widdowson, J., La Plante, P., Caldui, C., et al. (1996). Early environmental regulation of forebrain glucocorticoid gene expression: Implications for adrenocortical response to stress. Developmental Neuroscience, 18, 49-72.
76. Mesiano, S., & Jaffe, R. B. (1997). Developmental and functional biology of the primate fetal adrenal cortex. Endocrine Reviews, 18(18), 378-403.
77. Misra, D. P., O'Campo, P., & Strobino, D. (2001). Testing a sociomedical model for preterm delivery. Pediatric Perinatology and Epidemiology, 15, 110-122.
78. Moawad, A. H., Goldenberg, R. L., Mercer, B., Meis, P. J., Iams, J. D., Das, A., et al. (2002). The preterm prediction study: The value of serum alkaline phosphatase, alpha-fetoprotein, plasma corticotropin-releasing hormone, and other serum markers for the prediction of spontaneous preterm birth. American Journal of Obstetrics & Gynecology, 186(5), 990-996.
79. Modi, N., Lewis, H., Al-Naqeeb, N. M., Ajayi-Obe, M., Dore, C. J., & Rutherford, M. (2001). The effects of repeated antenatal glucocorticoid therapy on the developing brain. Pediatric Research, 50(5), 581-585.
80. Monk, C., Myers, M. M., Sloan, R. P., Ellman, L. M., & Fifer, W. P (2003). Effects of women's stress-elicited physiological activity and chronic anxiety on fetal heart rate. Journal of Developmental and Behavioral Pediatrics, 24(1), 32-38.
81. Monk, C. S., & Nelson, C. A. (2002). The effects of hydrocortisone on cognitive and neural function: A behavioral and event-related potential investigation. Neuropsychopharmacology, 26(4), 505-519.
82. Moss, T. J., Nitsos, I., Harding, R., & Newnham, J. P. (2003). Differential effects of maternal and fetal betamethasone injections in late-gestation fetal sheep. Journal of the Society for Gynecologic Investigation, 10, 474-479.
83. Moss, T. J., Sloboda, D. M., Gurrin, L. C., Harding, R., Challis, J. R., & Newnham, J. P. (2001). Programming effects in sheep of prenatal growth restriction and glucocorticoid exposure. American Journal of Physiology. Regulatory, Integrative, Comparative, and Physiology, 281(3), R960-R970.
84. Munck, A., Guyre, P. M., & Holbrook, N. J. (1984). Physiological functions of glucocorticoids in stress and their relation to pharmacological actions. Endocrine Reviews, 5(1), 25-44.
85. Muneoka, K., Mikuni, M., Ogawa, T., Kitera, K., Kamei, K., Takigawa, M., et al. (1997). Prenatal dexamethasone exposure alters brain monoamine metabolism and adrenocortical response in rat offspring. American Journal of Physiology, 273(5 Pt 2), R1669-R1675.
86. Murphy, B. P., Inder, T. E., Huppi, P. S., Warfield, S., Zientara, G. P., Kikinis, R., et al. (2001). Impaired cerebral cortical gray matter growth after treatment with dexamethasone for neonatal chronic lung disease. Pediatrics, 107(2), 217-221.
87. Newcomer, J. W., Craft, S., Hershey, T., Askins, K., & Bardgett, M. E. (1994). Glucocorticoid-induced impairment in declarative memory performance in adult humans. Neuroscience, 14(4), 2047-2053.
88. Ng, P.C., Lam, C. W, Lee, K. C., Ma, K. C., Fok, T. F., Chan, I. H., et al. (2002). Reference range and factors affecting the human corticotropin- releasing hormone test in preterm, very low birth weight infants. Journal of Clinical Endocrinology and Metabolism, 87(10), 4621-4628.
89. NIH Consensus Development Conference. (1995). Effects of corticosteroids for fetal maturation and perinatal outcomes. American Journal of Obstetrics & Gynecology, 173, 253-344.
90. Nyirenda, M. J., Lindsay, R. S., Kenyon, C. J., Burchell, A., & Seckl, J. R. (1998). Glucocorticoid exposure in late gestation permanently programmes rat hepatic phosphoenolpyruvate carboxykinase and glucocorticoid receptor expression causes glucose intolerance in adult offspring. Journal of Clinical Investigation, 101, 2174-2181.
91. Nyirenda, M. J., Welberg, L. A. M., & Seckl, J. R. (2001). Programming hyperglycaemia in the rat through prenatal exposure to glucocorticoids - Fetal effect or maternal influence? Journal of Endocrinology, 170(3), 653-660.
92. O'Connor, T. G., Heron, J., Golding, J., Beveridge, M., & Glover, V. (2002). Maternal antenatal anxiety and children's behavioural/emotional problems at 4 years: Report from the Avon Longitudinal study of Parents and Children. British Journal of Psychiatry, 180, 502-508.
93. Parker, C. R., Atkinson, M. W., Owen, J., & Andrews, W. W. (1996). Dynamics of the fetal adrenal, cholesterol, and apolipoprotein B responses to antenatal betamethasone therapy. American Journal of Obstetrics & Gynecology, 174(2), 562-565.
94. Paarlberg, M. K., Vingerhoets, J. J. M., Passchier, J., Dekker, G. A., & Van Geijn, H. P. (1995). Psychosocial factors and pregnancy outcome: A review with emphasis on methodological issues. Journal of Psychosomatic Research, 39(5), 563-595.
95. Peterson, B. S., Vohr, B., Staib, L. H., Cannistraci, C. J., Dolberg, A., Schneider, K. C., et al. (2000). Regional brain volume abnormalities and long-term cognitive outcome in preterm infants. Journal of American Medical Association, 284, 1939-1947.
96. Reinisch, J. M., Simon, N. G., & Karwo, W. G. (1978). Prenatal exposure to prednisone in humans and animals retards intrauterine growth. Science, 202(4366), 436-438.
97. Rini, C. K., Dunkel-Schetter, C., Wadhwa, P. D., & Sandman, C. A. (1999). Psychological adaptation and birth outcomes: The role of personal resources, stress, and sociocultural context during pregnancy. Health Psychology, 18(4), 333-345.
98. Rose, J. C., Schwartz, J., Green, J., & Kerr, D. R. (1998). Development of the corticotropin-releasing factor adrenocorticotropic hormone/beta-endorphin system in the mammalian fetus. In W. W. Fox (Ed.), Fetal and neonatal physiology (pp. 2431-2442). Philadelphia: WB Saunders.
99. Salm, A. K., Pavelko, Krose, E. M., Webster, W., Kraszpulski, M., & Birle, D. L. (2004). Lateral amygdaloid nucleus expansion in adult rats is associated with exposure to prenatal stress. Developmental Brain Research, 148, 159-167.
100. Sanchez, M. M., Young, L. J., Plotsky, P. M., & Insel, T. R. (2000). Distribution of corticosteroid receptors in the rhesus brain: Relative absence of glucocorticoid receptors in the hippocampal formation. The Journal of Neuroscience, 20(12), 4657-4668.
101. Sandman, C., A., Glynn, L., Wadhwa, P. D., Chicz-DeMet, A., Porto, M., & Garite, T. (2003). Maternal hypothalamic-pituitary-adrenal deregulation during the third trimester influences human fetal responses. Developmental Neuroscience, 25(1), 41-49.
102. Sandman, C. A., Wadhwa, P. D., Chicz-DeMet, A., Porto, M., & Garite, T. J. (1999). Maternal corticotropin-releasing hormone and habituation in the human fetus. Developmental Psychobiology, 34(3), 163-173.
103. Scheepens, A., van de Waarenburg, M., van den Hove, D., & Blanco, C. E. (2003). A single course of prenatal betamethasone In the rat alters postnatal brain cell proliferation but not apoptosis. Journal of Physiology, 552(1), 163-175.
104. Schmidt, L. A., Fox, N. A., Goldberg, M. C., Smith, C. C., & Schulkin, J. (1999). Effects of acute prednisone administration on memory, attention and emotion In healthy human adults. Psychoneuroendocrinalogy, 24(4), 461-483.
105. Schneider, M. L. (1992). Prenatal stress exposure alters postnatal behavioral expression under conditions of novelty challenge in rhesus monkey infants. Dettelopmental Psychobiology, 25(7), 529-540.
106. Schulkin, J. (1999). Corticotropin-releasing hormone signals adversity in both the placenta and the brain: Regulation by glucocorticoids and allostatic overload. Journal of Endocrinology, 161(3), 349-356.
107. Schwab, M., Schmidt, K., Roedel, M. A., Muller, T., Schubert, H., Buchwalder, L. F., et al. (2001). Non-linear changes of electrocortial activity after antenatal betamethasone treatment in fetal sheep. Journal of Physiology, 531, 535-543.
108. Shanks, N., Larocque, S., & Meaney, M. J. (1995). Neonatal endotoxin exposure alters the development of the hypothalamic-pituitary-adrenal axis: Early illness and later responsivity to stress. Journal of Neuroscience, 15, 376-384.
109. Sloboda, D. M., Moss, T. J., Gurrin, L. C., Newnham, J. P., & Challis, J. R. (2002). The effect of prenatal betamethasone administration on postnatal ovine hypothalamic-pituitary-adrenal function. Journal of Endocrinology, 172(1), 71-81.
110. Smith, R. (2001). The endocrinology of parturition. Newcastle, Australia: Karger.
111. Smith, R., Mesiano, S., & McGrath, S. (2003). Hormone trajectories leading to human birth. Regulatory Peptides, 108, 159-164.
112. Spinillo, A., Viazzo, F., Colleoni, R., Chiara, A., Cerbo, R. M., & Fazzi, E. (2004). Two-year infant neurodevelopmental outcome after single or multiple antenatal courses of corticosteroids to prevent complications of prematurity. American Journal of Obstetrics & Gynecology, 191(1), 217-224.
113. Thorp, J. A., Jones, P. G., Knox, E., & Clark, R. H. (2002). Does antenatal corticosteroid therapy affect birth weight and head circumference? Obstetrics & Gynecology, 99(1), 101-108.
114. Trautman, P. D., Meyer-Bahlburg, H. F., Postelnek, J., & New, M. I. (1995). Effects of early prenatal dexamethasone on the cognitive and behavioral development of young children: Results of a pilot study. Psychoneuroendocrinology, 20(4), 439-449.
115. Uno, H., Eisele, S., Sakai, A., Shelton, S., Baker, E., DeJesus, O., et al. (1994). Neurotoxicity of glucocorticoids in the primate brain. Hormone and Behavior, 28, 336-348.
116. Uno, H., Lohmiller, L., Thieme, C., Kemnitz, J. W., Engle, M. J., Roecker, E. B., et al. (1990). Brain damage induced by prenatal exposure to dexamethasone in fctal macaques. I. Hippocampus. Brain Research, Developmental Brain Research, 53, 157-167.
117. Van den Bergh, B. (1990). The influence of maternal emotions during pregnancy on fetal and neonatal behavior. Journal of Prenatal & Perinatal Psychology & Health, 5(2), 119-130.
118. Van den Bergh, B. R. H., & Marcoen, A. (2004). High antenatal maternal anxiety is related to ADHD symptoms, externalizing problems, and anxiety in 8/9-year-olds. Child Development, 75(4), 1085-1097.
119. Wadhwa, P. D., Garite, T. J., Porto, M., Glynn, L. M., Chicz-DeMet, A., Dunkel-Schetter, C, et al. (2004). Placental corticotropin-releasing hormone (CRH), spontaneous preterm birth and fetal growth restriction: A prospective investigation. American Journal of Obstetrics & Gynecology, 191, 1063-1069.
120. Ward, H. E., Johnson, E. A., Salm, A. K., & Birkle, D. L. (2000). Effects of prenatal stress on defensive withdrawal behavior and corticotropin releasing factor systems in rat brain. Physiology and Behavior, 70, 359-366.
121. Weinstock, M. (2001). Alterations induced by gestational stress in brain morphology and behaviour of the offspring. Progress in Neurobiology, 65(5), 427-451.
122. Welberg, L. A., & Seckl, J. (2001). Prenatal stress, glucocorticoids and the programming of the brain. Journal of Neuroendocrinology, 13, 113-128.
123. Welberg, L. A., Seckl, J. R., & Holmes, M. C. (2001). Prenatal glucocorticold programming of brain corticosteroid receptors and corticotrophin-releasing hormone: Possible implications for behaviour. Neuroscience, 104(1), 71-79.
124. Winter, S. D. W. (1998). Fetal and neonatal adrenocortical physiology. In W. W. Fox (Ed.), Fetal and neonatal physiology (pp. 378-403). Philadelphia: WB Saunders.
125. Wittekind, C. A., Arnold, J. D., Leslie, G. I., Luttrell, B., & Jones, M. P. (1993). Longitudinal study of plasma ACTH and cortisol in very low birth weight infants in the first 8 weeks of life. Early Human Development, 33(3), 191-200.
126. Wolf, O. T. (2003). HPA axis and memory. Bailliere's Best Practice & Research: Clinical Endocrinology 6 Metabolism, 17(2), 287-299.
127. Young, A. H., Sahakian, B. J., Robbins, T. W., & Cowen, P J. (1999). The effects of chronic administration of hydrocortisone on cognitive function in normal male volunteers. Psychopharmacology, 145(145), 260-266.
128. Zarrow, M. X., Philpott, J. E., & Denenberg, V. H. (1970). Passage of 14-C-4 corticosterone from the rat mother to the fetus and neonate. Nature, 226, 1058-1059.