The effect of prenatal betamethasone administration on postnatal ovine hypothalamic-pituitary-adrenal function

Journal of Endocrinology

Volumn 172, Issue 1, 2002, Pages 71-81

  Sloboda, D M ^a   Moss, T J ^a   Gurrin, L C ^a   Newnham, J P ^a   Challis, J R G ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARGIPRESSIN; BETAMETHASONE; CELESTONE CHRONODOSE; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; GLUCOCORTICOID; HYDROCORTISONE; MEDROXYPROGESTERONE ACETATE; SODIUM CHLORIDE; STEROID;

ANIMAL EXPERIMENT; ARTICLE; BIRTH; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; DRUG EFFECT; DRUG RESPONSE; ENDOCRINE FUNCTION; FEMALE; FETUS; FETUS WEIGHT; GESTATIONAL AGE; HYDROCORTISONE BLOOD LEVEL; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; MOTHER; NEWBORN; NONHUMAN; PERINATAL PERIOD; PREGNANCY; PRENATAL DEVELOPMENT; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; RANDOMIZATION; SHEEP;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; ARGININE VASOPRESSIN; BETAMETHASONE; CORTICOTROPIN-RELEASING HORMONE; FEMALE; FETUS; GLUCOCORTICOIDS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INJECTIONS; PITUITARY-ADRENAL SYSTEM; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RANDOM ALLOCATION; SHEEP; TIME FACTORS;

EID: 0036150161     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1720071     Document Type: Article

References (47)

1. Scientific basis and therapeutic regimens for use of antenatal glucocorticoids
2. In utero programming of chronic disease
3. Preterm newborn lambs renal and cardiovascular responses after fetal or maternal antenatal betamethasone
4. Morphometric analyses of adrenal gland growth in fetal and neonatal sheep I. The adrenal cortex
5. Effects of CRF, AVP and opioid peptides on pituitary adrenal responses in sheep
6. Dual function of 11β hydroxysteroid dehydrogenase in placenta: Modulating placental glucocorticoid passage and local steroid action
7. Maturation and activation of hypothalamic-pituitary-adrenal function in fetal sheep
8. Modulation by cortisol of adrenocorticotrophin-induced activation of adrenal function in fetal sheep
9. Regulation of corticosteroids in the fetus: Control of birth and influence of adult disease
10. The preterm prediction study: Maternal stress is associated with spontaneous preterm birth at less than thirty-five weeks gestation
11. Dysfunction of placental glucocorticoid barrier: Link between fetal environment and adult hypertension?
12. Low doses of dexamethasone suppress pituitary adrenal function but augment the glycemic response to acute hypoxemia in fetal sheep during late gestation
13. Developmental regulation of corticotrophin receptor (ACTH-R) gene expression in the adrenal gland of the ovine fetus and newborn lamb: Effect of hypoxia during late pregnancy
14. Repeated antenatal corticosteroids: Size at birth and subsequent development
15. Effect of maternal nutrient restriction in early gestation on hypothalamic pituitary adrenal axis responses during acute hypoxemia in late gestation fetal sheep
16. Effect of maternal nutrient restriction in early gestation on development of the hypothalamic pituitary adrenal axis in fetal sheep at 0.8-8.9 of gestation
17. Effects of incremental cortisol and adrenalectomy on plasma corticosteroid binding capacity in fetal sheep
18. Single and repetitive maternal glucocorticoid exposures reduce fetal growth in sheep
19. Fetal versus maternal and gestational age effects of repetitive antenatal glucocorticoids
20. Long-term effects of betamethasone on fetal development
21. Maternal protein restriction influences the programming of the rat hypothalamic-pituitary-adrenal axis
22. Time course of changes in lung mechanics following fetal steroid treatment
23. Dexamethasone in the last week of pregnancy attenuates hippocampal glucocorticoid receptor gene expression and elevates blood pressure in the adult offspring in the rat
24. A controlled trial of antepartum glucocorticoid treatment for prevention of the respiratory distress syndrome in premature infants
25. Maternal nutrient restriction (48H) modifies brain corticosteroid receptor expression and endocrine function in the fetal guinea pig
26. CRH and AVP-induced changes in synthesis and release of ACTH from the ovine fetal pituitary in vitro: Negative influences of cortisol
27. Repeated prenatal maternal but not fetal, injections of corticosteroid reduce term birth weight, increase gestational length and cause a transient reduction in blood pressure during postnatal development in sheep
28. Programming effects in sheep of prenatal growth restriction and glucocorticoid exposure
29. Induction of premature delivery in sheep following infusion of cortisol to the fetus: The effect of maternal progestagen on the C21-steroid-17αhydroxylase, C17, 20 lyase and aromatase pathways
30. Maternal, but not fetal, administration of corticosteroids restricts fetal growth
31. Synergism between systemic corticotrophin-releasing factor and arginine vasopressin on adrenocorticotrophin release in vivo varies as a function of gestational age in the ovine fetus
32. Changes in pituitary responses to synthetic ovine corticotrophin releasing factor in fetal sheep
33. Elevated plasma cortisol concentrations: A link between low birth weight and the insulin resistance syndrome?
34. Glucocorticoids enhance corticotrophin receptor mRNA levels in ovine adrenocortical cells
35. Prenatal exposure to prednisone in humans and animals retards intrauterine growth
36. In vivo evidence for increased adrenal sensitivity to adrenocorticotrophin (1-24) in the lamb fetus late in gestation
37. Glucocorticoids, feto-placental 11β-hydroxysteroid dehydrogenase type 2, and the early life origins of adult disease
38. Metabolism of dexamethasone: Sites and activity in mammalian tissues
39. Effects of repeated maternal betamethasone administration on growth and hypothalamic-pituitary-adrenal function of the ovine fetus at term
40. Prenatal programming of postnatal glucose tolerance in sheep
41. 11β-Hydroxysteroid dehydrogenase in human fetal tissues
42. Early developmental and temporal characteristics of stress-induced secretion of pituitary adrenal hormones in prenatally stressed rat pups
43. Brain damage induced by prenatal exposure to dexamethasone in fetal rhesus macaques. I. Hippocampus
44. Neurotoxicity of glucocorticoids in the primate brain
45. Long-term effects of prenatal stress and handling on metabolic parameters; relationship to corticosterone secretion response
46. Prenatal stress selectively alters the reactivity of the hypothalamic-pituitary-adrenal system in the female rat
47. Regulation and function of the fetal adrenal gland in sheep