Effects on ion permeation with hydrophobic substitutions at a residue in shaker S6 that interacts with a signature sequence amino acid

Annals of the New York Academy of Sciences

Volumn 868, Issue , 1999, Pages 458-464

  Zei, Paul C ^a   Ogielska, Eva M ^a   Hoshi, Toshinori ^b   Aldrich, Richard W ^a  

^a STANFORD UNIVERSITY   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL; POTASSIUM ION; VOLTAGE GATED CHANNEL FORMING PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; CONFERENCE PAPER; CONTROLLED STUDY; HYDROPHOBICITY; NONHUMAN; POTASSIUM CONDUCTANCE; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

ANIMALIA;

EID: 0033009896     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb11314.x     Document Type: Conference Paper

References (20)

1. Hille, B. 1973. J. Gen. Physiol. 61: 669-686.
2. Blatz, A. L. & K. Magleby. 1984. J Gen. Physiol. 84: 1-23.
3. Heginbotham, L. & R. MacKinnon. 1993. Biophys. J. 65: 2089-2096.
4. MacKinnon, R. 1991. Nature 350: 232-235.
5. Liman, E.R. et al. 1992. Neuron 9: 861-871.
6. Kavanaugh, M.P. et al. 1992. Neuron 8: 493-497.
7. Doyle, D.A. et al. 1998. Science 280: 69-77.
8. Heginbotham, L. & R. MacKinnon. 1994. Science 258: 1152-1155.
9. Choi, K.L. et al. 1993. Neuron 10: 533-541.
10. Lopez, G. et al. 1994. Nature 367: 179-182.
11. Tagliatela, M. et al. 1994. J. Biol. Chem. 269: 13867-13873.
12. Aiyar, J. et al. 1994. Biophys. J. 67: 2261-2264.
13. Liu, Y. et al. 1997. Neuron 19: 175-184.
14. Liu, Y. & R.H. Joho. 1998. Pflügers Arch. 435: 654-661.
15. Hoshi, T. et al. 1991. Neuron 7: 547-556.
16. Avdonin, V. et al. 1997. J. Gen. Physiol. 109; 169-180.
17. Ogielska, E.M. & R.W. Aldrich. 1998. J. Gen. Physiol. 112: 243-257.
18. Ogielska, E.M. & R.W. Aldrich. Unpublished observations.
19. MacKinnon, R. 1998. Personal communication.
20. Ogielska, E.M. & R.W. Aldrich. 1998. J. Gen. Physiol. In press.