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Volumn 27, Issue 1-4, 2006, Pages 213-230

Mechanisms of adenosine-induced cytotoxicity and their clinical and physiological implications

Author keywords

Adenosine; Clinical uses; Cytotoxicity; Extracellular ATP (ATPo); P1 receptors; P2 receptors; Pyrimidine starvation

Indexed keywords

2' DEOXYADENOSINE 3' PHOSPHATE; ADENINE; ADENOSINE; ADENOSINE A2 RECEPTOR; ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE RECEPTOR; ADENOSINE TRIPHOSPHATE; ADENOSYLHOMOCYSTEINASE; ALKALINE PHOSPHATASE; CYCLIC AMP; DEOXYADENOSINE; DEOXYADENOSINE DIPHOSPHATE; DEOXYADENOSINE TRIPHOSPHATE; DNA; GUANOSINE PHOSPHATE; HISTAMINE; HYPOXANTHINE; INOSINE; INOSINE PHOSPHATE; LEUKOTRIENE DERIVATIVE; NUCLEOSIDE DERIVATIVE; OXYGEN RADICAL; PURINE; PYRIMIDINE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; UNINDEXED DRUG; URIC ACID; XANTHINE;

EID: 33748925074     PISSN: 09516433     EISSN: None     Source Type: Journal    
DOI: 10.1002/biof.5520270119     Document Type: Article
Times cited : (13)

References (109)
  • 5
    • 0031154752 scopus 로고    scopus 로고
    • Effects of extracellular ATP and adenosine on different thymocyte subsets
    • S.G. Apasov, M. Koshiba, T.M. Chused and M.V. Sitkovsky, Effects of extracellular ATP and adenosine on different thymocyte subsets, Journal of Immunology 158 (1997), 5095-5105.
    • (1997) Journal of Immunology , vol.158 , pp. 5095-5105
    • Apasov, S.G.1    Koshiba, M.2    Chused, T.M.3    Sitkovsky, M.V.4
  • 6
    • 0021814769 scopus 로고
    • An analysis of multiple mechanisms of adenosine toxicity in Baby Hamster Kidney cells
    • S. Archer, P. Juranka, J.H. Ho and V. Chan, An analysis of multiple mechanisms of adenosine toxicity in Baby Hamster Kidney cells, Journal of Cell Physiology 124 (1985), 226-232.
    • (1985) Journal of Cell Physiology , vol.124 , pp. 226-232
    • Archer, S.1    Juranka, P.2    Ho, J.H.3    Chan, V.4
  • 7
    • 33645953293 scopus 로고    scopus 로고
    • Overexpression of ecto-protein kinases in prostasomes of metastatic cell origin
    • Abstract- Epub ahead of print
    • A.A. Babiker, G. Ronquist, B. Nilsson and K.N. Ekdahl, Overexpression of ecto-protein kinases in prostasomes of metastatic cell origin, Prostate (2006), Abstract- Epub ahead of print.
    • (2006) Prostate
    • Babiker, A.A.1    Ronquist, G.2    Nilsson, B.3    Ekdahl, K.N.4
  • 8
    • 0026452386 scopus 로고
    • Deoxyadenosine toxicity in an adenosine deaminase-inhibited human CCRF-CEM T-lymphoblastoid cell line causes cell swelling
    • A.S. Bagnara, L.E. McDonald and H.M. Slade, Deoxyadenosine toxicity in an adenosine deaminase-inhibited human CCRF-CEM T-lymphoblastoid cell line causes cell swelling, Biochimica Biophysica Acta 1180 (1992), 163-172.
    • (1992) Biochimica Biophysica Acta , vol.1180 , pp. 163-172
    • Bagnara, A.S.1    McDonald, L.E.2    Slade, H.M.3
  • 9
    • 0028266960 scopus 로고
    • Release of intracellular calcium and stimulation of cell growth by ATP and histamine in human ovarian cancer cells
    • S. Batra and I. Fadeel, Release of intracellular calcium and stimulation of cell growth by ATP and histamine in human ovarian cancer cells, Cancer Letters 77 (1994), 57-63.
    • (1994) Cancer Letters , vol.77 , pp. 57-63
    • Batra, S.1    Fadeel, I.2
  • 11
    • 0029114967 scopus 로고
    • p53 expression is required for thymocyte apoptosis induced by adenosine deaminase deficiency
    • P. Benveniste and A. Cohen, p53 expression is required for thymocyte apoptosis induced by adenosine deaminase deficiency, Proceedings of the National Academy of Science USA 92 (1995), 8373-8377.
    • (1995) Proceedings of the National Academy of Science USA , vol.92 , pp. 8373-8377
    • Benveniste, P.1    Cohen, A.2
  • 12
    • 0006731668 scopus 로고    scopus 로고
    • Leukemias
    • P. Calabresi and P.S. Schein, eds, McGraw-Hill, Inc., New York
    • C.D. Bloomfield, K.A. Foon and E.G. Levine, Leukemias, in: Medical Oncology, P. Calabresi and P.S. Schein, eds, McGraw-Hill, Inc., New York, 1993, pp. 459-492.
    • Medical Oncology , vol.1993 , pp. 459-492
    • Bloomfield, C.D.1    Foon, K.A.2    Levine, E.G.3
  • 13
    • 0027787739 scopus 로고
    • The role of pharmacogenetics in chemotherapy: Modulation of tumour response and host toxicity
    • A.V. Boddy and J.R. Idle, The role of pharmacogenetics in chemotherapy: modulation of tumour response and host toxicity, Cancer Surv. 117 (1993), 79-103.
    • (1993) Cancer Surv. , vol.117 , pp. 79-103
    • Boddy, A.V.1    Idle, J.R.2
  • 14
    • 0025193106 scopus 로고
    • P2 purinoceptors on vascular endothelial cells: Physiological significance and transduction mechanisms
    • J.M. Boeynames and J.D. Pearson, P2 purinoceptors on vascular endothelial cells: Physiological significance and transduction mechanisms, Trends in Pharmacological Sciences 11 (1990), 34-37.
    • (1990) Trends in Pharmacological Sciences , vol.11 , pp. 34-37
    • Boeynames, J.M.1    Pearson, J.D.2
  • 15
    • 0004593318 scopus 로고
    • Pharmacology of antineoplastic agents
    • P. Calabresi and P.S. Schein, eds, McGraw-Hill, Inc., New York
    • P. Calabresi, J. Clark, A.R. Hanauske and M.C. Wiemann, Pharmacology of antineoplastic agents, in: Medical Oncology, P. Calabresi and P.S. Schein, eds, McGraw-Hill, Inc., New York, 1993, pp. 263-287.
    • (1993) Medical Oncology , pp. 263-287
    • Calabresi, P.1    Clark, J.2    Hanauske, A.R.3    Wiemann, M.C.4
  • 16
    • 0026606151 scopus 로고
    • The purine analogs - A therapeutic beauty contest
    • B.D. Cheson, The purine analogs - a therapeutic beauty contest, Journal of Clinical Oncology 10 (1992), 352-355.
    • (1992) Journal of Clinical Oncology , vol.10 , pp. 352-355
    • Cheson, B.D.1
  • 21
    • 0026507232 scopus 로고
    • Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors
    • B.N. Cronstein, R.I. Levin, M.R. Philips, R. Hirschhorn, S.B. Abramson and G. Weisman, Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors, Journal of Immunology 148 (1992), 2201-2206.
    • (1992) Journal of Immunology , vol.148 , pp. 2201-2206
    • Cronstein, B.N.1    Levin, R.I.2    Philips, M.R.3    Hirschhorn, R.4    Abramson, S.B.5    Weisman, G.6
  • 22
    • 0026592425 scopus 로고
    • Stimulus-response uncoupling in the neutrophil, Adenosine A2-receptor occupancy inhibits the sustained, but not the early, events of stimulus transduction in human neutrophils by a mechanism independent of actin-filament formation
    • B.N. Cronstein and K.A. Haines, Stimulus-response uncoupling in the neutrophil, Adenosine A2-receptor occupancy inhibits the sustained, but not the early, events of stimulus transduction in human neutrophils by a mechanism independent of actin-filament formation, Biochemical Journal 281 (1992), 631-635.
    • (1992) Biochemical Journal , vol.281 , pp. 631-635
    • Cronstein, B.N.1    Haines, K.A.2
  • 23
    • 0025829211 scopus 로고
    • Extracellular metabolism of adenine nucleotides and adenosine in the innervated skeletal muscle of the frog
    • R.A. Cunha and A.M. Sebastiao, Extracellular metabolism of adenine nucleotides and adenosine in the innervated skeletal muscle of the frog, European Journal of Pharmacology 197 (1991), 83-92.
    • (1991) European Journal of Pharmacology , vol.197 , pp. 83-92
    • Cunha, R.A.1    Sebastiao, A.M.2
  • 24
    • 0028581975 scopus 로고
    • Receptors for adenine nucleotides and nucleosides: Subclassification, distribution and molecular characterisation
    • H.H. Dalziel and D.P. Westfall, Receptors for adenine nucleotides and nucleosides: subclassification, distribution and molecular characterisation, Pharmacological Reviews 46 (1994), 449-466.
    • (1994) Pharmacological Reviews , vol.46 , pp. 449-466
    • Dalziel, H.H.1    Westfall, D.P.2
  • 25
    • 0030826888 scopus 로고    scopus 로고
    • Extracellular ATP and adenosine cause apoptosis of pulmonary artery endothelial cells
    • D.D. Dawicki, D. Chatterjee, J. Wyche and S. Rounds, Extracellular ATP and adenosine cause apoptosis of pulmonary artery endothelial cells, American Journal of Physiology 273 (1997), L485-L494.
    • (1997) American Journal of Physiology , vol.273
    • Dawicki, D.D.1    Chatterjee, D.2    Wyche, J.3    Rounds, S.4
  • 28
    • 0027440979 scopus 로고
    • Cell death initiated by 3-deazaadenosine in HL-60 cells is apoptosis and is partially inhibited by homocysteine
    • P.C. Endresen, T.J. Eide and J. Aarbakke, Cell death initiated by 3-deazaadenosine in HL-60 cells is apoptosis and is partially inhibited by homocysteine, Biochemical Pharmacology 46 (1993), 1893-1901.
    • (1993) Biochemical Pharmacology , vol.46 , pp. 1893-1901
    • Endresen, P.C.1    Eide, T.J.2    Aarbakke, J.3
  • 29
    • 0035877185 scopus 로고    scopus 로고
    • Involvement of A3 receptors in the potentiation by adenosine of the inhibitory effect of theophylline on human eosinophil degranulation: Possible novel mechanism of the anti-inflammatory action of theophylline
    • C.I. Ezeamuzie, Involvement of A3 receptors in the potentiation by adenosine of the inhibitory effect of theophylline on human eosinophil degranulation: possible novel mechanism of the anti-inflammatory action of theophylline, Biochemical Pharmacology 61 (2001), 1551-1559.
    • (2001) Biochemical Pharmacology , vol.61 , pp. 1551-1559
    • Ezeamuzie, C.I.1
  • 30
    • 0037449867 scopus 로고    scopus 로고
    • Positive coupling of atypical adenosine A3 receptors on human eosinophils to adenylyl cyclase
    • C.I. Ezeamuzie and E. Philips, Positive coupling of atypical adenosine A3 receptors on human eosinophils to adenylyl cyclase, Biochemical and Biophysical Research Communications 300 (2003), 712-718.
    • (2003) Biochemical and Biophysical Research Communications , vol.300 , pp. 712-718
    • Ezeamuzie, C.I.1    Philips, E.2
  • 31
    • 0026610294 scopus 로고
    • P2-purinergic receptor agonists inhibit the growth of androgen-independent prostate carcinoma cells
    • W.G. Fang, F. Pirnia, Y.J. Bang, C.E. Myers and J.B. Trepel, P2-purinergic receptor agonists inhibit the growth of androgen-independent prostate carcinoma cells, Journal of Clinical Investigation 89 (1992), 191-196.
    • (1992) Journal of Clinical Investigation , vol.89 , pp. 191-196
    • Fang, W.G.1    Pirnia, F.2    Bang, Y.J.3    Myers, C.E.4    Trepel, J.B.5
  • 32
    • 0027279128 scopus 로고
    • Bcl-2 modulation of apoptosis induced by anticancer drugs: Resistance to thymidylate stress is independent of classical resistance pathways
    • T.C. Fisher, A.E. Milner, C.D. Gregory, A.L. Jackman, G.W. Aherne, J.A. Hartley, C. Dive and J.A. Hickman, Bcl-2 modulation of apoptosis induced by anticancer drugs: resistance to thymidylate stress is independent of classical resistance pathways, Cancer Research 53 (1993), 3321-3326.
    • (1993) Cancer Research , vol.53 , pp. 3321-3326
    • Fisher, T.C.1    Milner, A.E.2    Gregory, C.D.3    Jackman, A.L.4    Aherne, G.W.5    Hartley, J.A.6    Dive, C.7    Hickman, J.A.8
  • 33
    • 0017794615 scopus 로고
    • The role of adenosine and 2′-deoxyadenosine in mammalian cells
    • I.H. Fox and W.N. Kelley, The role of adenosine and 2′- deoxyadenosine in mammalian cells, Annual Review of Biochemistry 47 (1978), 655-686.
    • (1978) Annual Review of Biochemistry , vol.47 , pp. 655-686
    • Fox, I.H.1    Kelley, W.N.2
  • 34
    • 0025755609 scopus 로고
    • The overexpression of the 3′ terminal region of the CDC25 gene of Saccharomyces cerevisiae causes growth inhibition and alteration of purine nucleotides
    • G. Frascotti, P. Coccetti, M.A. Vanoni, L. Alberghina and E. Martegani, The overexpression of the 3′ terminal region of the CDC25 gene of Saccharomyces cerevisiae causes growth inhibition and alteration of purine nucleotides, Biochimica Biophysica Acta 1089 (1991), 206-212.
    • (1991) Biochimica Biophysica Acta , vol.1089 , pp. 206-212
    • Frascotti, G.1    Coccetti, P.2    Vanoni, M.A.3    Alberghina, L.4    Martegani, E.5
  • 35
    • 0029097199 scopus 로고
    • Activation of cell growth inhibitor by ectoprotein kinase-mediated phosphorylation in transformed mouse fibroblasts
    • I. Friedberg, I. Belzer, O. Oged-Plesz and D. Kuebler, Activation of cell growth inhibitor by ectoprotein kinase-mediated phosphorylation in transformed mouse fibroblasts, Journal of Biological Chemistry 270 (1995), 20560-20567.
    • (1995) Journal of Biological Chemistry , vol.270 , pp. 20560-20567
    • Friedberg, I.1    Belzer, I.2    Oged-Plesz, O.3    Kuebler, D.4
  • 36
    • 2942541730 scopus 로고    scopus 로고
    • Is type 2 diabetes mellitus a vascular disease (atheroscleropathy) with hyperglycaemia a late manifestation? The role of NOS, NO and redox stress
    • BioMed Central-Open Access
    • M.R. Hayden and S.C. Tyagi, Is type 2 diabetes mellitus a vascular disease (atheroscleropathy) with hyperglycaemia a late manifestation? The role of NOS, NO and redox stress, Cardiovascular Diabetology 2 (2003), 2, BioMed Central-Open Access.
    • (2003) Cardiovascular Diabetology , vol.2 , pp. 2
    • Hayden, M.R.1    Tyagi, S.C.2
  • 37
    • 0031149046 scopus 로고    scopus 로고
    • The c-Jun transcription factor-bipotential mediator of neuronal death, survival and regeneration
    • T. Herdegen, P. Skene and M. Bahr, The c-Jun transcription factor-bipotential mediator of neuronal death, survival and regeneration, Trends in Neurosciences 20 (1997), 227-231.
    • (1997) Trends in Neurosciences , vol.20 , pp. 227-231
    • Herdegen, T.1    Skene, P.2    Bahr, M.3
  • 38
    • 0028062055 scopus 로고
    • 2-Chloroadenosine inhibits the MHC-unrestricted cytolytic activity of anti-CD3-activated killer cells: Evidence for the involvement of a non-A1/A2 cell-surface adenosine receptor
    • D.W. Hoskin, T. Reynolds and T. Blay, 2-Chloroadenosine inhibits the MHC-unrestricted cytolytic activity of anti-CD3-activated killer cells: evidence for the involvement of a non-A1/A2 cell-surface adenosine receptor, Cellular Immunology 159 (1994), 85-93.
    • (1994) Cellular Immunology , vol.159 , pp. 85-93
    • Hoskin, D.W.1    Reynolds, T.2    Blay, T.3
  • 39
    • 0016382304 scopus 로고
    • Mechanism of inhibition of bacterial growth by adenine
    • R. Hosono and S. Kuno, Mechanism of inhibition of bacterial growth by adenine, Journal of Biochemistry 75 (1974), 215-220.
    • (1974) Journal of Biochemistry , vol.75 , pp. 215-220
    • Hosono, R.1    Kuno, S.2
  • 47
    • 0032486367 scopus 로고    scopus 로고
    • Adenosine induces apotosis by inhibiting mRNA and protein synthesis in chick embryonic sympathetic neurons
    • J.S. Kulkarni, D.A. Przywara, T.D. Wakade and A.R. Wakade, Adenosine induces apotosis by inhibiting mRNA and protein synthesis in chick embryonic sympathetic neurons, Neuroscience Letters 248 (1998), 187-190.
    • (1998) Neuroscience Letters , vol.248 , pp. 187-190
    • Kulkarni, J.S.1    Przywara, D.A.2    Wakade, T.D.3    Wakade, A.R.4
  • 48
    • 0025821202 scopus 로고
    • Inhibition of 2-desamino-2-2-methyl-10-propagyl-5,8-dideazafolic acid cytotoxicity by 5,10-dideazatetrahydrofolate in L1210 cells with decrease in DNA fragmentation and deoxyadenosine triphosphate pools
    • J.B. Kwok and M.H. Tattersall, Inhibition of 2-desamino-2-2-methyl-10- propagyl-5,8-dideazafolic acid cytotoxicity by 5,10-dideazatetrahydrofolate in L1210 cells with decrease in DNA fragmentation and deoxyadenosine triphosphate pools, Biochemical Pharmacology 42 (1991), 507-513.
    • (1991) Biochemical Pharmacology , vol.42 , pp. 507-513
    • Kwok, J.B.1    Tattersall, M.H.2
  • 49
    • 0026597120 scopus 로고
    • DNA fragmentation, dATP pool elevation and potentiation of antifolate cytotoxicity in L1210 cells by hypoxanthine
    • J.B. Kwok and M.H. Tattersall, DNA fragmentation, dATP pool elevation and potentiation of antifolate cytotoxicity in L1210 cells by hypoxanthine, British Journal of Cancer 65 (1992), 503-508.
    • (1992) British Journal of Cancer , vol.65 , pp. 503-508
    • Kwok, J.B.1    Tattersall, M.H.2
  • 50
    • 0028307259 scopus 로고
    • Decrease in equilibrative uridine transport during monocytic differentiation of HL-60 leukaemia: Involvement of protein kinase C
    • C. Lee, Decrease in equilibrative uridine transport during monocytic differentiation of HL-60 leukaemia: involvement of protein kinase C, Biochemical Journal 300 (1994), 407-412.
    • (1994) Biochemical Journal , vol.300 , pp. 407-412
    • Lee, C.1
  • 53
    • 0016778808 scopus 로고
    • Effect of adenosine on the adenine nucleotide content and metabolism of hepatocytes
    • P. Lund, N.W. Cornell and H.A. Krebs, Effect of adenosine on the adenine nucleotide content and metabolism of hepatocytes, Biochemical Journal 152 (1975), 593-599.
    • (1975) Biochemical Journal , vol.152 , pp. 593-599
    • Lund, P.1    Cornell, N.W.2    Krebs, H.A.3
  • 55
    • 0019521591 scopus 로고
    • Clinical pharmacology of deoxycoformycin
    • P.P. Major, R.P. Agarwal and D.W. Kufe, Clinical pharmacology of deoxycoformycin, Blood 58 (1981), 91-96.
    • (1981) Blood , vol.58 , pp. 91-96
    • Major, P.P.1    Agarwal, R.P.2    Kufe, D.W.3
  • 57
    • 0036676924 scopus 로고    scopus 로고
    • Spontaneous oxidative stress and liver tumours in mice lacking methionine adenosyltransferase 1A
    • M.L. Martinez-Chantar, Spontaneous oxidative stress and liver tumours in mice lacking methionine adenosyltransferase 1A, FASEB Journal 16 (2002), 1292-1294.
    • (2002) FASEB Journal , vol.16 , pp. 1292-1294
    • Martinez-Chantar, M.L.1
  • 59
    • 0016665063 scopus 로고
    • Release of adenosine by hypoxic canine lung tissue and its possible role in pulmonary circulation
    • R.M. Mentzer, R. Rubio and R.M. Berne, Release of adenosine by hypoxic canine lung tissue and its possible role in pulmonary circulation, American Journal of Physiology 229 (1975), 1625-1631.
    • (1975) American Journal of Physiology , vol.229 , pp. 1625-1631
    • Mentzer, R.M.1    Rubio, R.2    Berne, R.M.3
  • 64
    • 2142657911 scopus 로고    scopus 로고
    • Acidic sphigomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis
    • M. Montserrat, A. Colell, A. Morales, C. Paneda, I. Varela-Nieto, C. Garcia-Ruiz and J.C. Fernandez-Checa, Acidic sphigomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis, Journal of Clinical Investigation 113 (2004), 895-904.
    • (2004) Journal of Clinical Investigation , vol.113 , pp. 895-904
    • Montserrat, M.1    Colell, A.2    Morales, A.3    Paneda, C.4    Varela-Nieto, I.5    Garcia-Ruiz, C.6    Fernandez-Checa, J.C.7
  • 68
    • 0030702041 scopus 로고    scopus 로고
    • Structure-function analysis of inhibitory adenosine receptor regulation
    • T.M. Palmer and G.L. Stiles, Structure-function analysis of inhibitory adenosine receptor regulation, Neuropharmacology 36 (1997), 1141-1147.
    • (1997) Neuropharmacology , vol.36 , pp. 1141-1147
    • Palmer, T.M.1    Stiles, G.L.2
  • 69
    • 0023758320 scopus 로고
    • 2-Chlorodeoxyadenosine: An effective new agent for the treatment of chronic lymphocytic leukaemia
    • L.D. Piro, C.J. Carrera, E. Beutler and D.A. Carson, 2- chlorodeoxyadenosine: an effective new agent for the treatment of chronic lymphocytic leukaemia, Blood 72 (1988), 1069-1073.
    • (1988) Blood , vol.72 , pp. 1069-1073
    • Piro, L.D.1    Carrera, C.J.2    Beutler, E.3    Carson, D.A.4
  • 70
    • 0025274664 scopus 로고
    • Lasting remissions in hairy-cell leukaemia induced by single infusion of 2-chlorodeoxyadenosine
    • L.D. Piro, C.J. Carrera, D.A. Carson and E. Beutler, Lasting remissions in hairy-cell leukaemia induced by single infusion of 2-chlorodeoxyadenosine, New England Journal of Medicine 322 (1992), 1117-1121.
    • (1992) New England Journal of Medicine , vol.322 , pp. 1117-1121
    • Piro, L.D.1    Carrera, C.J.2    Carson, D.A.3    Beutler, E.4
  • 71
    • 77957077456 scopus 로고
    • Permeation of nucleosides, nucleic acid bases, and nucleotides in animal cells
    • P.G.W. Plagemann and R.M. Wohlhueter, Permeation of nucleosides, nucleic acid bases, and nucleotides in animal cells, Current Topics in Membranes 14 (1980), 225-330.
    • (1980) Current Topics in Membranes , vol.14 , pp. 225-330
    • Plagemann, P.G.W.1    Wohlhueter, R.M.2
  • 72
    • 0017186880 scopus 로고
    • Inhibition of phosphoribosylpyrophosphate synthesis by purine nucleosides in human erythrocytes
    • G. Planet and I.H. Fox, Inhibition of phosphoribosylpyrophosphate synthesis by purine nucleosides in human erythrocytes, Journal of Biological Chemistry 251 (1976), 5839-5844.
    • (1976) Journal of Biological Chemistry , vol.251 , pp. 5839-5844
    • Planet, G.1    Fox, I.H.2
  • 73
    • 0018885429 scopus 로고
    • Comparison of the toxicity and metabolism of 9-β-D-Arabinofuranosyl- 2-fluoroadenine and 9-β-D-Arabinofuranosyladenine in human lymphoblastoid cells
    • W. Plunkett, S. Chubb, L. Alexander and J.A. Montgomery, Comparison of the toxicity and metabolism of 9-β-D-Arabinofuranosyl-2-fluoroadenine and 9-β-D-Arabinofuranosyladenine in human lymphoblastoid cells, Cancer Research 40 (1980), 2349-2355.
    • (1980) Cancer Research , vol.40 , pp. 2349-2355
    • Plunkett, W.1    Chubb, S.2    Alexander, L.3    Montgomery, J.A.4
  • 74
    • 0031754497 scopus 로고    scopus 로고
    • Receptors for purines and pyrimidines
    • V. Ralevic and G. Burnstock, Receptors for purines and pyrimidines, Pharmacolgical Reviews 50 (1998), 413-492.
    • (1998) Pharmacolgical Reviews , vol.50 , pp. 413-492
    • Ralevic, V.1    Burnstock, G.2
  • 76
    • 0019120629 scopus 로고
    • Compartmentalized ATP pools produced from adenosine are nuclear pools
    • E. Rapaport, Compartmentalized ATP pools produced from adenosine are nuclear pools, Journal of Cellular Physiology 105 (1980), 267-274.
    • (1980) Journal of Cellular Physiology , vol.105 , pp. 267-274
    • Rapaport, E.1
  • 77
    • 0020683915 scopus 로고
    • Treatment of human tumour cells with ADP or ATP yields arrest of growth in the S-phase of the cell cycle
    • E. Rapaport, Treatment of human tumour cells with ADP or ATP yields arrest of growth in the S-phase of the cell cycle, Journal of Cellular Physiology 114 (1983), 279-283.
    • (1983) Journal of Cellular Physiology , vol.114 , pp. 279-283
    • Rapaport, E.1
  • 78
    • 1542730150 scopus 로고
    • Anticancer activities of adenine nucleotides in mice are mediated through expansion of erythrocyte ATP pools
    • E. Rapaport and J. Fontaine, Anticancer activities of adenine nucleotides in mice are mediated through expansion of erythrocyte ATP pools, Proceedings of the National Academy of Science USA 86 (1989), 1662-1666.
    • (1989) Proceedings of the National Academy of Science USA , vol.86 , pp. 1662-1666
    • Rapaport, E.1    Fontaine, J.2
  • 80
  • 81
    • 0016683809 scopus 로고
    • Relationship between adenosine concentration and oxygen supply in rat brain
    • R. Rubio, R.M. Berne, E.I. Bockman and R.R. Curnish, Relationship between adenosine concentration and oxygen supply in rat brain, American Journal of Physiology 228 (1975), 1896-1902.
    • (1975) American Journal of Physiology , vol.228 , pp. 1896-1902
    • Rubio, R.1    Berne, R.M.2    Bockman, E.I.3    Curnish, R.R.4
  • 82
    • 0035865184 scopus 로고    scopus 로고
    • Extracellular adenosine-induced apoptosis in mouse neuroblastoma cells studies on involvement of adenosine receptors and adenosine uptake
    • S.M. Schrier, E.W. van Tilburg, H. van der Meulen, A.P. IJzerman, G.J. Mulder and J.F. Nagelkerke, Extracellular adenosine-induced apoptosis in mouse neuroblastoma cells studies on involvement of adenosine receptors and adenosine uptake, Biochemical Pharmacology 61 (2001), 417-425.
    • (2001) Biochemical Pharmacology , vol.61 , pp. 417-425
    • Schrier, S.M.1    Van Tilburg, E.W.2    Van Der Meulen, H.3    Ijzerman, A.P.4    Mulder, G.J.5    Nagelkerke, J.F.6
  • 83
    • 0022992945 scopus 로고
    • The effects of adenosine agonists on human neutrophil function
    • D.J. Schrier and K.M. Imre, The effects of adenosine agonists on human neutrophil function, Journal of Immunology 137 (1986), 3284-3289.
    • (1986) Journal of Immunology , vol.137 , pp. 3284-3289
    • Schrier, D.J.1    Imre, K.M.2
  • 84
    • 0037087594 scopus 로고    scopus 로고
    • Apoptosis induced by extracellular ATP in the mouse neuroblastoma cell line N1E-115: Studies on involvement of P2 receptors and adenosine
    • S.M. Schrier, B.I. Florea, G.J. Mulder, J.F. Nagelkerke and A.P. IJzerman, Apoptosis induced by extracellular ATP in the mouse neuroblastoma cell line N1E-115: studies on involvement of P2 receptors and adenosine, Biochemical Pharmacology 63 (2002), 1119-1126.
    • (2002) Biochemical Pharmacology , vol.63 , pp. 1119-1126
    • Schrier, S.M.1    Florea, B.I.2    Mulder, G.J.3    Nagelkerke, J.F.4    Ijzerman, A.P.5
  • 85
    • 0032544374 scopus 로고    scopus 로고
    • Growth inhibition of HL-60 cells by extracellular ATP: Concentration-dependent involvement of a P2 receptor and adenosine generation
    • S.P. Seetulsingh-Goorah and B.W. Stewart, Growth inhibition of HL-60 cells by extracellular ATP: concentration-dependent involvement of a P2 receptor and adenosine generation, Biochemical Biophysical Research Communications 250 (1998), 390-396.
    • (1998) Biochemical Biophysical Research Communications , vol.250 , pp. 390-396
    • Seetulsingh-Goorah, S.P.1    Stewart, B.W.2
  • 86
    • 0344279663 scopus 로고    scopus 로고
    • Growth inhibition of HL-60 cells by extracellular ATP and adenosine: Role of pyrimidine starvation and implications regarding ATP analogues as preferred antileukaemic agents
    • S.P. Seetulsingh-Goorah and B.W. Stewart, Growth inhibition of HL-60 cells by extracellular ATP and adenosine: Role of pyrimidine starvation and implications regarding ATP analogues as preferred antileukaemic agents, Cancer Forum 21 (1997), 84.
    • (1997) Cancer Forum , vol.21 , pp. 84
    • Seetulsingh-Goorah, S.P.1    Stewart, B.W.2
  • 87
    • 0006587284 scopus 로고    scopus 로고
    • Scleroderma
    • S. Ruddy, E.D. Harris and C.B. Sledge, eds, WB Saunders, Philadelphia
    • J.R. Seibold, Scleroderma, in: Kelley's Textbook of Rheumatology, (Vol. 2), S. Ruddy, E.D. Harris and C.B. Sledge, eds, WB Saunders, Philadelphia, 2000, pp. 1211-1239.
    • (2000) Kelley's Textbook of Rheumatology , vol.2 , pp. 1211-1239
    • Seibold, J.R.1
  • 88
    • 0022003367 scopus 로고
    • Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to non-dividing human lymphocytes
    • S. Seto, J. Carrera, M. Kubota, D.B. Wasson and D.A. Carson, Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to non-dividing human lymphocytes, Journal of Clinical Investigation 75 (1985), 377-383.
    • (1985) Journal of Clinical Investigation , vol.75 , pp. 377-383
    • Seto, S.1    Carrera, J.2    Kubota, M.3    Wasson, D.B.4    Carson, D.A.5
  • 89
    • 33646378412 scopus 로고    scopus 로고
    • Mining literature for a comprehensive pathway analysis: A case study for retrieval of homocysteine-related genes for genetic and epigenetic studies
    • BioMed Central- Open Access
    • P. Sharma, R.D. Senthilkumar, V. Brahmachari, E. Sundaramoorthy, A. Mahajan, A. Sharma and S. Sengupta, Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine-related genes for genetic and epigenetic studies, Lipids in Health and Disease 5 (2006), 1. - BioMed Central- Open Access.
    • (2006) Lipids in Health and Disease , vol.5 , pp. 1
    • Sharma, P.1    Senthilkumar, R.D.2    Brahmachari, V.3    Sundaramoorthy, E.4    Mahajan, A.5    Sharma, A.6    Sengupta, S.7
  • 90
    • 0017157251 scopus 로고
    • The adenosine-like effect of exogenous cyclic AMP upon nucleotide and PP-Ribose-P concentrations of cultured human lymphoblasts
    • F.F. Snyder and J.E. Seegmiller, The adenosine-like effect of exogenous cyclic AMP upon nucleotide and PP-Ribose-P concentrations of cultured human lymphoblasts, FEBS Letters 66 (1976), 102-106.
    • (1976) FEBS Letters , vol.66 , pp. 102-106
    • Snyder, F.F.1    Seegmiller, J.E.2
  • 91
    • 0033942755 scopus 로고    scopus 로고
    • Distributional changes of purinergic receptor subtypes (P2X 1-7) in uterine epithelial cells during early pregnancy
    • M. Slater, J.A. Barden and C.R. Murphy, Distributional changes of purinergic receptor subtypes (P2X 1-7) in uterine epithelial cells during early pregnancy, Histochemical Journal 32 (2000), 365-372.
    • (2000) Histochemical Journal , vol.32 , pp. 365-372
    • Slater, M.1    Barden, J.A.2    Murphy, C.R.3
  • 92
    • 0033711974 scopus 로고    scopus 로고
    • The purinergic calcium channels P2X1,2,5,7 are down-regulated while P2X3, 4, 6 are up-regulated during apoptosis in the ageing rat prostate
    • M. Slater, J.A. Barden and C.R. Murphy, The purinergic calcium channels P2X1,2,5,7 are down-regulated while P2X3, 4, 6 are up-regulated during apoptosis in the ageing rat prostate, Histochemical Journal 32 (2000), 571-580.
    • (2000) Histochemical Journal , vol.32 , pp. 571-580
    • Slater, M.1    Barden, J.A.2    Murphy, C.R.3
  • 93
    • 0028568104 scopus 로고
    • 2+-mediated mechanisms
    • 2+-mediated mechanisms, Biochemical Journal 304 (1994), 877-885.
    • (1994) Biochemical Journal , vol.304 , pp. 877-885
    • Szondy, Z.1
  • 96
    • 0032476788 scopus 로고    scopus 로고
    • Adenosine and ADP prevent apoptosis in cultured rat cerebellar granule cells
    • O.V. Vitolo, M.T. Ciotti, C. Galli, T. Borsello and P. Calissano, Adenosine and ADP prevent apoptosis in cultured rat cerebellar granule cells, Brain Research 809 (1998), 297-301.
    • (1998) Brain Research , vol.809 , pp. 297-301
    • Vitolo, O.V.1    Ciotti, M.T.2    Galli, C.3    Borsello, T.4    Calissano, P.5
  • 97
    • 0025997351 scopus 로고
    • Adenine nucleotide degradation in cultured chick heart muscle cells
    • B. Wagenknecht and M. Lieberman, Adenine nucleotide degradation in cultured chick heart muscle cells, Molecular and Cellular Biochemistry 107 (1991), 119-125.
    • (1991) Molecular and Cellular Biochemistry , vol.107 , pp. 119-125
    • Wagenknecht, B.1    Lieberman, M.2
  • 98
    • 28644439712 scopus 로고    scopus 로고
    • Inhibitory effects of extracellular adenosine triphosphate on growth of esophageal carcinoma cells
    • M.X. Wang, L.M. Ren and B.E. Shan, Inhibitory effects of extracellular adenosine triphosphate on growth of esophageal carcinoma cells, World Journal of Gastroenterology 11 (2005), 5915-5919.
    • (2005) World Journal of Gastroenterology , vol.11 , pp. 5915-5919
    • Wang, M.X.1    Ren, L.M.2    Shan, B.E.3
  • 100
    • 0032555440 scopus 로고    scopus 로고
    • Adenosine protects chick embryonic sympathetic neurons from apoptotic death by 2′-deoxyadenosine - Importance of ATP in apoptosis
    • A.R. Wakade, T.D. Wakade and J.S. Kulkarni, Adenosine protects chick embryonic sympathetic neurons from apoptotic death by 2′-deoxyadenosine - importance of ATP in apoptosis, Neuroscience Letters 252 (1998), 63-166.
    • (1998) Neuroscience Letters , vol.252 , pp. 63-166
    • Wakade, A.R.1    Wakade, T.D.2    Kulkarni, J.S.3
  • 101
    • 0035318769 scopus 로고    scopus 로고
    • Adenosine inhibits neutrophil vascular endothelial growth factor release and transendothelial migration via A2B receptor activation
    • A. Wakai, J.H. Wang, D.C. Winter, J.T. Street, R.G. O'Sullivan and H.P. Redmond, Adenosine inhibits neutrophil vascular endothelial growth factor release and transendothelial migration via A2B receptor activation, Shock 15 (2001), 297-301.
    • (2001) Shock , vol.15 , pp. 297-301
    • Wakai, A.1    Wang, J.H.2    Winter, D.C.3    Street, J.T.4    O'Sullivan, R.G.5    Redmond, H.P.6
  • 102
    • 0026844113 scopus 로고
    • A2-adenosine receptor stimulation increases macromolecule permeability of coronary endothelial cells
    • H. Watanabe, W. Kuhne, P. Schwartz and H.M. Piper, A2-adenosine receptor stimulation increases macromolecule permeability of coronary endothelial cells. American Journal of Physiology 262 (1992), H1174-H1181.
    • (1992) American Journal of Physiology , vol.262
    • Watanabe, H.1    Kuhne, W.2    Schwartz, P.3    Piper, H.M.4
  • 103
    • 0024238623 scopus 로고
    • Growth inhibition of transformed mouse fibroblasts by adenine nucleotides occurs via generation of extracellular adenosine
    • G.A. Weisman, K.D. Lustig, E. Lane, N.N. Huang, I. Belzer and I. Friedberg, Growth inhibition of transformed mouse fibroblasts by adenine nucleotides occurs via generation of extracellular adenosine, Journal of Biological Chemistry 263 (1988), 12367-12372.
    • (1988) Journal of Biological Chemistry , vol.263 , pp. 12367-12372
    • Weisman, G.A.1    Lustig, K.D.2    Lane, E.3    Huang, N.N.4    Belzer, I.5    Friedberg, I.6
  • 104
    • 0344826090 scopus 로고    scopus 로고
    • Extracellular ATP and adenosine induce cell apoptosis of human hepatoma Li-7A cells via the A3 adenosine receptor
    • L.T. Wen and A.F. Knowles, Extracellular ATP and adenosine induce cell apoptosis of human hepatoma Li-7A cells via the A3 adenosine receptor, British Journal of Pharmacology 140 (2003), 1009-1018.
    • (2003) British Journal of Pharmacology , vol.140 , pp. 1009-1018
    • Wen, L.T.1    Knowles, A.F.2
  • 106
    • 0032538046 scopus 로고    scopus 로고
    • Nucleotide metabolizing ectoenzymes are upregulated in A431 cells periodically treated with cytostatic ATP leading to partial resistance without preventing apoptosis
    • H.S. Wiendl, C. Schneider and A. Ogilvie, Nucleotide metabolizing ectoenzymes are upregulated in A431 cells periodically treated with cytostatic ATP leading to partial resistance without preventing apoptosis, Biochimica Biophysica Acta 230 (1998), 282-298.
    • (1998) Biochimica Biophysica Acta , vol.230 , pp. 282-298
    • Wiendl, H.S.1    Schneider, C.2    Ogilvie, A.3
  • 107
    • 0027156894 scopus 로고
    • Kinetic characterization of adenosine A2 receptor-mediated relaxation in isolated rabbit aorta
    • H.L. Wiener and G.P. Thalody, Kinetic characterization of adenosine A2 receptor-mediated relaxation in isolated rabbit aorta, European Journal of Pharmacology 238 (1993), 65-74.
    • (1993) European Journal of Pharmacology , vol.238 , pp. 65-74
    • Wiener, H.L.1    Thalody, G.P.2
  • 108
    • 0029927229 scopus 로고    scopus 로고
    • Deoxynucleotide pool depletion and sustained inhibition of ribonucleotide reductase and DNA synthesis after treatment of human lymphoblastoid cells with 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine
    • K.C. Xie and W. Plunkett, Deoxynucleotide pool depletion and sustained inhibition of ribonucleotide reductase and DNA synthesis after treatment of human lymphoblastoid cells with 2-chloro-9-(2-deoxy-2-fluoro-β-D- arabinofuranosyl)adenine, Cancer Research 56 (1996), 3030-3037.
    • (1996) Cancer Research , vol.56 , pp. 3030-3037
    • Xie, K.C.1    Plunkett, W.2
  • 109
    • 0027955309 scopus 로고
    • Purinergic axis in cardiac blood vessels: Agonist-mediated release of ATP from cardiac endothelial cells
    • S. Yang, D.J. Cheek, D.P. Westfall and I.L. Buxton, Purinergic axis in cardiac blood vessels: agonist-mediated release of ATP from cardiac endothelial cells, Circulation Research 74 (1994), 401-407.
    • (1994) Circulation Research , vol.74 , pp. 401-407
    • Yang, S.1    Cheek, D.J.2    Westfall, D.P.3    Buxton, I.L.4


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