Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis

Journal of Clinical Investigation

Volumn 113, Issue 6, 2004, Pages 895-904

  Marí, Montserrat ^a   Colell, Anna ^a   Morales, Albert ^a   Pañeda, Covadonga ^b   Varela Nieto, Isabel ^b   García Ruiz, Carmen ^a,c   Fernández Checa, José C ^a,c  

^a HOSPITAL CLÍNIC   (Spain)

^b INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

^c INST D INVESTIGACIONS B   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; METHIONINE ADENOSYLTRANSFERASE; METHIONINE ADENOSYLTRANSFERASE 1A; S ADENOSYLMETHIONINE; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AMINO ACID SYNTHESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAUSE OF DEATH; CELL CULTURE; CHRONIC LIVER DISEASE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; HEPATITIS; IN VIVO STUDY; LIVER CELL; LIVER INJURY; MALE; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT;

ACETYLTRANSFERASES; ANIMALS; ANTINEOPLASTIC AGENTS; DOWN-REGULATION; HEPATITIS; MICE; MICE, KNOCKOUT; S-ADENOSYLMETHIONINE; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 2142657911     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200419852     Document Type: Article

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