Adenosine kinase inhibition promotes survival of fetal adenosine deaminase-deficient thymocytes by blocking dATP accumulation

Journal of Clinical Investigation

Volumn 110, Issue 3, 2002, Pages 395-402

  Van De Wiele, C Justin ^a,b,f   Vaughn, James G ^a   Blackburn, Michael R ^c   Ledent, Catherine A ^d   Jacobson, Marlene ^e   Jiang, Hong ^a,g   Thompson, Linda F ^a,b  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^d UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^e MERCK RESEARCH LABORATORIES   (United States)

^f UNIVERSITY OF OKLAHOMA   (United States)

^g Curatek Pharmaceuticals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5' AMINO 5' DEOXYADENOSINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE DEAMINASE; ADENOSINE DEAMINASE INHIBITOR; ADENOSINE KINASE INHIBITOR; ADENOSINE RECEPTOR BLOCKING AGENT; ADENOSINE RECEPTOR STIMULATING AGENT; DNA; PENTOSTATIN; PROTEIN BCL 2; RNA; T LYMPHOCYTE RECEPTOR; XANTHINE DERIVATIVE;

ANIMAL CELL; ARTICLE; ENZYME INHIBITION; ENZYME SUBSTRATE; GENE EXPRESSION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; THYMOCYTE; THYMUS;

EID: 0036327878     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI0215683     Document Type: Article

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