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Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 3, 2002, Pages 1194-1199

Discrimination against purine-pyrimidine mispairs in the polymerase active site of DNA polymerase I: A structural explanation

(5) Minnick, Dana T a,c Liu, Lixing b,d Grindley, Nigel D F b Kunkel, Thomas A a Joyce, Catherine M b

a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES (United States)

b YALE UNIVERSITY (United States)

c GLAXOSMITHKLINE (United States)

d Alkermes Incorporated (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINO ACID; DEOXYADENOSINE TRIPHOSPHATE; DEOXYCYTIDINE TRIPHOSPHATE; DEOXYGUANOSINE TRIPHOSPHATE; DEOXYRIBOSE; DNA DIRECTED DNA POLYMERASE BETA; GLUTAMINE; PURINE; PYRIMIDINE; THYMIDINE TRIPHOSPHATE;

AMINO ACID SUBSTITUTION; ARTICLE; BASE MISPAIRING; CONTROLLED STUDY; DNA TEMPLATE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; GENE MUTATION; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; BASE PAIR MISMATCH; BINDING SITES; DEOXYRIBONUCLEOTIDES; DNA POLYMERASE I; KINETICS; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PURINES; PYRIMIDINES; RECOMBINANT PROTEINS;

EID: 0037022239 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.032457899 Document Type: Article

Times cited : (44)

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