Crystal Structures of a Ligand-free MthK Gating Ring: Insights into the Ligand Gating Mechanism of K+ Channels

Cell

Volumn 126, Issue 6, 2006, Pages 1161-1173

  Ye, Sheng ^a   Li, Yang ^a   Chen, Liping ^a   Jiang, Youxing ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CALCIUM TRANSPORT; CONFORMATION; CRYSTAL STRUCTURE; ELECTROPHYSIOLOGY; LIGAND BINDING; NONHUMAN; PH; PRIORITY JOURNAL; PROKARYOTE; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

PROKARYOTA;

EID: 33748622291     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2006.08.029     Document Type: Article

References (43)

1. + transporter: multiple conformations of an octameric ring. Cell 126 (2006) 1147-1159 this issue
2. + export systems in Escherichia coli. J. Bacteriol. 169 (1987) 3743-3749
3. Bao L., Rapin A.M., Holmstrand E.C., and Cox D.H. Elimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity. J. Gen. Physiol. 120 (2002) 173-189
4. Bateman A., Birney E., Durbin R., Eddy S.R., Howe K.L., and Sonnhammer E.L. The Pfam protein families database. Nucleic Acids Res. 28 (2000) 263-266
5. Bellamacina C.R. The nicotinamide dinucleotide binding motif: a comparison of nucleotide binding proteins. FASEB J. 10 (1996) 1257-1269
6. 2+-dependent activation. Proc. Natl. Acad. Sci. USA 98 (2001) 4776-4781
7. CCP4 (Collaborative Computational Project, Number 4). The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D Biol. Crystallogr. 50 (1994) 760-763
8. del Camino D., and Yellen G. Tight steric closure at the intracellular activation gate of a voltage-gated K(+) channel. Neuron 32 (2001) 649-656
9. + channel and its structural implications. Nature 403 (2000) 321-325
10. Ding S., Ingleby L., Ahern C.A., and Horn R. Investigating the putative glycine hinge in Shaker potassium channel. J. Gen. Physiol. 126 (2005) 213-226
11. 2+ on gating ring stability. J. Biol. Chem. 280 (2005) 41716-41724
12. + conduction and selectivity. Science 280 (1998) 69-77
13. Heginbotham L., LeMasurier M., Kolmakova-Partensky L., and Miller C. Single streptomyces lividans K(+) channels: functional asymmetries and sidedness of proton activation. J. Gen. Physiol. 114 (1999) 551-560
14. + sensitivity in E. coli. FEBS Lett. 547 (2003) 165-169
15. + channel and demonstration of its presence in the human BK channel. Neuron 29 (2001) 593-601
16. Jiang Y., Lee A., Chen J., Cadene M., Chait B.T., and MacKinnon R. Crystal structure and mechanism of a calcium-gated potassium channel. Nature 417 (2002) 515-522
17. Jiang Y., Lee A., Chen J., Cadene M., Chait B.T., and MacKinnon R. The open pore conformation of potassium channels. Nature 417 (2002) 523-526
18. Jin T., Peng L., Mirshahi T., Rohacs T., Chan K.W., Sanchez R., and Logothetis D.E. The (beta)gamma subunits of G proteins gate a K(+) channel by pivoted bending of a transmembrane segment. Mol. Cell 10 (2002) 469-481
19. + conduit in vivo. EMBO J. 22 (2003) 4049-4058
20. Kuo M.M., Haynes W.J., Loukin S.H., Kung C., and Saimi Y. Prokaryotic K(+) channels: from crystal structures to diversity. FEMS Microbiol. Rev. 29 (2005) 961-985
21. + channel. Neuron 19 (1997) 175-184
22. Liu Y.S., Sompornpisut P., and Perozo E. Structure of the KcsA channel intracellular gate in the open state. Nat. Struct. Biol. 8 (2001) 883-887
23. + channels. Biochemistry 43 (2004) 13242-13247
24. Magleby K.L. Gating mechanism of BK (Slo1) channels: so near, yet so far. J. Gen. Physiol. 121 (2003) 81-96
25. McCoy A.J., Grosse-Kunstleve R.W., Storoni L.C., and Read R.J. Likelihood-enhanced fast translation functions. Acta Crystallogr. D Biol. Crystallogr. 61 (2005) 458-464
26. McRee D.E. XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density. J. Struct. Biol. 125 (1999) 156-165
27. Munro A.W., Ritchie G.Y., Lamb A.J., Douglas R.M., and Booth I.R. The cloning and DNA sequence of the gene for the glutathione-regulated potassium-efflux system KefC of Escherichia coli. Mol. Microbiol. 5 (1991) 607-616
28. Nakamura T., Yuda R., Unemoto T., and Bakker E.P. KtrAB, a new type of bacterial K(+)-uptake system from Vibrio alginolyticus. J. Bacteriol. 180 (1998) 3491-3494
29. Niu X., Qian X., and Magleby K.L. Linker-gating ring complex as passive spring and Ca(2+)-dependent machine for a voltage- and Ca(2+)-activated potassium channel. Neuron 42 (2004) 745-756
30. Otwinowski Z., and Minor W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276 (1997) 307-326
31. +-channel activation gating. Science 285 (1999) 73-78
32. Perrakis A., Harkiolaki M., Wilson K.S., and Lamzin V.S. ARP/wARP and molecular replacement. Acta Crystallogr. D Biol. Crystallogr. 57 (2001) 1445-1450
33. Pico, A. (2003). RCK domain model of calcium activation in BK channels. PhD thesis, Rockefeller University, New York.
34. + channel RCK domain with charged membrane surfaces. Biochemistry 44 (2005) 62-71
35. Roosild T.P., Miller S., Booth I.R., and Choe S. A mechanism of regulating transmembrane potassium flux through a ligand-mediated conformational switch. Cell 109 (2002) 781-791
36. +-channel flux: a structural perspective. Trends Biochem. Sci. 29 (2004) 39-45
37. Rossmann M.G., Moras D., and Olsen K.W. Chemical and biological evolution of nucleotide-binding protein. Nature 250 (1974) 194-199
38. + in bacterial transport. Mol. Microbiol. 9 (1993) 533-543
39. Schreiber M., and Salkoff L. A novel calcium-sensing domain in the BK channel. Biophys. J. 73 (1997) 1355-1363
40. Storoni L.C., McCoy A.J., and Read R.J. Likelihood-enhanced fast rotation functions. Acta Crystallogr. D Biol. Crystallogr. 60 (2004) 432-438
41. Xia X.M., Zeng X., and Lingle C.J. Multiple regulatory sites in large-conductance calcium-activated potassium channels. Nature 418 (2002) 880-884
42. + channels; a molecular switch for electrical signaling. Neuron 41 (2004) 859-865
43. + channel-Fab complex at 2.0 Å resolution. Nature 414 (2001) 43-48