AMPK regulation of the growth of cultured human keratinocytes

Biochemical and Biophysical Research Communications

Volumn 349, Issue 2, 2006, Pages 519-524

  Saha, Asish K ^a   Persons, Kelly ^a   Safer, Joshua D ^a   Luo, Zhijun ^a   Holick, Michael F ^a   Ruderman, Neil B ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acetyl CoA carboxylase; AICAR; AMP activated protein kinase; Malonyl CoA; Troglitazone; Vitamin D3

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; 5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ACETYL COENZYME A CARBOXYLASE; ADENYLATE KINASE; CALCITRIOL; MALONYL COENZYME A; TROGLITAZONE; VITAMIN D;

ARTICLE; CELL ENERGY; CELL GROWTH; CELL PROLIFERATION; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; KERATINOCYTE; PRIORITY JOURNAL;

ANIMALS; CHOLECALCIFEROL; CHROMANS; CULTURE MEDIA; FIBRINOLYTIC AGENTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; KERATINOCYTES; MALONYL COENZYME A; MICE; MULTIENZYME COMPLEXES; NIH 3T3 CELLS; PROTEIN-SERINE-THREONINE KINASES; THIAZOLIDINEDIONES; VITAMIN D;

EID: 33748561175     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.08.107     Document Type: Article

References (34)

1. Hardie D.G., and Carling D. The AMP-activated protein kinase-fuel gauge of the mammalian cell?. Eur. J. Biochem. 246 (1997) 259-273
2. Motoshima H., Goldstein B.J., Igata M., and Araki E.H. AMPK and cell proliferation-AMPK as a therapeutic target for atherosclerosis and cancer. J. Physiol. 574 (2006) 63-71
3. Itani S.I., Saha A.K., Kurowski T.G., Coffin H.R., Tornheim K., and Ruderman N.B. Glucose autoregulates its uptake in skeletal muscle: involvement of AMP-activated protein kinase. Diabetes 52 (2003) 1635-1640
4. Hardie D.G., Scott J.W., Pan D.A., and Hudson E.R. Management of cellular energy by the AMP-activated protein kinase system. FEBS Lett. 546 (2003) 113-120
5. Kemp B.E., Stapleton D., Campbell D.J., Chen Z.P., Murthy S., Walter M., Gupta A., Adams J.J., Katsis F., Van Denderen B., Jennings I.G., Iseli T., Michell B.J., and Witters L.A. AMP-activated protein kinase, super metabolic regulator. Biochem. Soc. Trans. 31 (2003) 162-168
6. Winder W.W. Energy-sensing and signaling by AMP-activated protein kinase in skeletal muscle. J. Appl. Physiol. 91 (2001) 1017-1028
7. Ruderman N.B., Saha A.K., Vavvas D., and Witters L.A. Malonyl-CoA, fuel sensing, and insulin resistance. Am. J. Physiol. 276 (1999) E1-E18
8. Tomas E., Tsao T.S., Saha A.K., Murrey H.E., Zhang C.C., Itani S.I., Lodish H.F., and Ruderman N.B. Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc. Natl. Acad. Sci. USA 99 (2002) 16309-16313
9. Bolster D.R., Crozier S.J., Kimball S.R., and Jefferson RL.S. S AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling. J. Biol. Chem. 277 (2002) 23977-23980
10. Xiang X., Saha A.K., Wen R., Ruderman N.B., and Luo Z. AMP-activated protein kinase activators can inhibit the growth of prostate cancer cells by multiple mechanisms. Biochem. Biophys. Res. Commun. 321 (2004) 161-167
11. Luo Z., Saha A.K., Xiang X., and Ruderman N.B. AMPK, the metabolic syndrome and cancer. Trends Pharmacol. Sci. 26 (2005) 69-76
12. Wang W., Yang X., De Silanes I.L., Carling D., and Gorospe M. Increased AMP:ATP ratio and AMP-activated protein kinase activity during senescence linked to reduced HuR function. J. Biol. Chem. 278 (2003) 27016-27023
13. 3. Br. J. Dermatol. 143 (2000) 72-78
14. 3 and its analogues in the treatment of psoriasis. Retinoid 14 (1998) 12-17
15. Safer J.D., Crawford T.M., Fraser L.M., Hoa M., Ray S., Chen T.C., Persons K., and Holick M.F. Thyroid hormone action on skin: diverging effects of topical versus intraperitoneal administration. Thyroid 13 (2003) 159-165
16. McGarry J.D., Stark M.J., and Foster D.W. Hepatic malonyl-CoA levels of fed, fasted and diabetic rats as measured using a simple radioisotopic assay. J. Biol. Chem. 253 (1978) 8291-8293
17. Saha A.K., Kurowski T.G., and Ruderman N.B. A malonyl-CoA fuel-sensing mechanism in muscle: effects of insulin, glucose, and denervation. Am. J. Physiol. 269 (1995) E283-E289
18. Fryer L.G., Parbu-Patel A., and Carling D. The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways. J. Biol. Chem. 277 (2002) 25226-25232
19. Saha A.K., Avilucea P., Ye J.-M., Assifi M.M., Kraegen E.W., and Ruderman N.B. Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo. Biochem. Biophys. Res. Commun. 314 (2004) 580-585
20. Nawrocki A.R., Rajala M.W., Tomas E., Pajvani U.B., Saha A.K., Treumbauer M.E., Pang Z., Chen A.S., Ruderman N.B., Chen H., and Scherer P.E. Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to PPARγ-agonists. J. Biol. Chem. 281 (2006) 2654-2660
21. Bhagavathula N., Nerusu K.C., Lai A., Ellis C.N., Chittiboyina A., Avery M.A., Benson H.S.C., Pershadsingh H.A., Kurtz T.W., and Varani J. Rosiglitazone inhibits proliferation, motility and matrix metalloproteinase production in keratinocytes. J. Invest. Dermatol. 122 (2004) 130-139
22. Imamura K., Ogura T., Kishimoto T., Kaminishi M., and Esumi H. Cell cycle regulation via p53 phosphorylation by a 5′-AMP activated protein kinase activator, 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranoside, in a human hepatocellular carcinoma cell line. Biochem. Biophys. Res. Commun. 287 (2001) 562-567
23. Swinnen J.V., Beckers A., Brusselmans K., Orange S., Segers J., Timmermans L., Vanderhoydonc F., Deboel L., Derua R., Waelkens E., De Schrijver E., Van de sande T., Noël A., Foufelle F., and Verhoeven G. Mimicry of a cellular low energy status blocks tumor cell anabolism and suppresses the malignant phenotype. Cancer Res. 65 (2005) 2441-2448
24. Rattan R., Giri S., Singh A.K., and Singh I. 5-Aminoimidazole-4-carboxamide-1-beta-d-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase. J. Biol. Chem. 280 (2005) 39582-39593
25. LeBrasseur N.K., Kelly M., Tsao T.-S., Farmer S.R., Saha A.K., Ruderman N.B., and Tomas E. Thiazolidinediones can rapidly activate AMP-activated protein kinase in mammalian tissues. Am. J. Physiol. 291 (2006) E175-E181
26. He G., Sung Y.M., DiGiovanni J., and Fischer S.M. Thiazolidinones inhibit insulin-like growth factor-1-induced activation of p70S6 kinase and suppress insulin-like growth factor-1 tumor-promoting activity. Cancer Res. 66 (2006) 1873-1879
27. Holick M.F. Vitamin D: a millennium perspective. J. Cell. Biochem. 88 (2003) 296-307
28. 3 in prostate cancer cells. J. Steroid Biochem. Mol. Biol. 85 (2003) 1-8
29. Yamauchi T., Kamon J., Minokoshi Y., Ito Y., Waki H., Uchida S., Yamashita S., Noda M., Kita S., and Ueki K. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat. Med. 8 (2002) 1288-1295
30. Ellis C.N., Varani J., Fisher G.J., Zeigler M.E., Pershadsingh H.A., Benson S.C., Chi Y., and Kurtz T.W. Troglitazone improves psoriasis and normalizes models of proliferative skin disease; ligands for peroxisome proliferators-activated receptor-γ inhibit keratinocyte proliferation. Arch. Dermatol. 136 (2003) 609-616
31. Ido Y., Carling D., and Ruderman N.B. Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation. Diabetes 51 (2002) 159-167
32. Cacicedo J.M., Yagihashi N., Keaney Jr. J.F., Ruderman N.B., and Ido Y. AMPK inhibits fatty acid-induced increases in NF-kappaB transactivation in cultured human umbilical vein endothelial cells. Biochem. Biophys. Res. Commun. 324 (2004) 1204-1209
33. Suzuki A., Kusakai G., Kishimoto A., Minegichi Y., Ogura T., and Esumi H. Induction of cell-cell detachment during glucose starvation through F-actin conversion by SNARK, the fourth member of the AMP-activated protein kinase catalytic subunit family. Biochem. Biophys. Res. Commun. 311 (2003) 156-161
34. Shaw R.J., Kosmatka M., Bardeesy N., Hurley R.L., Witters L.A., DePinho R.A., and Cantley L.C. The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. Proc. Natl. Acad. Sci. USA 100 (2004) 3329-3335