메뉴 건너뛰기




Volumn 291, Issue 3, 2006, Pages

Postnatal environment overrides genetic and prenatal factors influencing offspring obesity and insulin resistance

Author keywords

Agouti related peptide; Development; Diet induced obesity; Hypothalamus; Leptin; Milk; Plasticity

Indexed keywords

FATTY ACID; INSULIN; LEPTIN RECEPTOR; NEUROPEPTIDE;

EID: 33748450150     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00138.2006     Document Type: Article
Times cited : (180)

References (70)
  • 1
    • 0001475715 scopus 로고    scopus 로고
    • Guiding principles for research involving animals and human beings
    • American Physiological Society. Guiding principles for research involving animals and human beings. Am J Physiol Regul Integr Comp Physiol 283: R281-R283, 2002.
    • (2002) Am J Physiol Regul Integr Comp Physiol , vol.283
  • 2
    • 17744375347 scopus 로고    scopus 로고
    • Regulation of neuronal and glial proteins by leptin: Implications for brain development
    • Ahima RS, Bjorbaek C, Osei S, and Flier JS. Regulation of neuronal and glial proteins by leptin: implications for brain development. Endocrinology 140: 2755-2762, 1999.
    • (1999) Endocrinology , vol.140 , pp. 2755-2762
    • Ahima, R.S.1    Bjorbaek, C.2    Osei, S.3    Flier, J.S.4
  • 3
    • 2642579261 scopus 로고    scopus 로고
    • Hypothalamic gene expression is altered in underweight but obese juvenile male Sprague-Dawley rats fed a high-energy diet
    • Archer ZA, Rayner DV, and Mercer JG. Hypothalamic gene expression is altered in underweight but obese juvenile male Sprague-Dawley rats fed a high-energy diet. J Nutr 134: 1369-1374, 2004.
    • (2004) J Nutr , vol.134 , pp. 1369-1374
    • Archer, Z.A.1    Rayner, D.V.2    Mercer, J.G.3
  • 4
    • 0031038124 scopus 로고    scopus 로고
    • Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats
    • Borg MA, Sherwin RS, Borg WP, Tamborlane WV, and Shulman GI. Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats. J Clin Invest 99: 361-365, 1997.
    • (1997) J Clin Invest , vol.99 , pp. 361-365
    • Borg, M.A.1    Sherwin, R.S.2    Borg, W.P.3    Tamborlane, W.V.4    Shulman, G.I.5
  • 5
    • 0028931891 scopus 로고
    • Local ventromedial hypothalamic glucopenia triggers counterregulatory hormone release
    • Borg WP, Sherwin RS, During MJ, Borg MA, and Shulman GI. Local ventromedial hypothalamic glucopenia triggers counterregulatory hormone release. Diabetes 44: 180-184, 1995.
    • (1995) Diabetes , vol.44 , pp. 180-184
    • Borg, W.P.1    Sherwin, R.S.2    During, M.J.3    Borg, M.A.4    Shulman, G.I.5
  • 7
    • 1642349297 scopus 로고    scopus 로고
    • Formation of projection pathways from the arcuate nucleus of the hypothalamus to hypothalamic regions implicated in the neural control of feeding behavior in mice
    • Bouret SG, Draper SJ, and Simerly RB. Formation of projection pathways from the arcuate nucleus of the hypothalamus to hypothalamic regions implicated in the neural control of feeding behavior in mice. J Neurosci 24: 2797-2805, 2004.
    • (2004) J Neurosci , vol.24 , pp. 2797-2805
    • Bouret, S.G.1    Draper, S.J.2    Simerly, R.B.3
  • 8
    • 1842536210 scopus 로고    scopus 로고
    • Trophic action of leptin on hypothalamic neurons that regulate feeding
    • Bouret SG, Draper SJ, and Simerly RB. Trophic action of leptin on hypothalamic neurons that regulate feeding. Science 304: 108-110, 2004.
    • (2004) Science , vol.304 , pp. 108-110
    • Bouret, S.G.1    Draper, S.J.2    Simerly, R.B.3
  • 11
    • 0032962123 scopus 로고    scopus 로고
    • GLUT-4, tumor necrosis factor, essential fatty acids and dafgenes and their role in insulin resistance and non-insulin dependent diabetes mellitus
    • Das UN. GLUT-4, tumor necrosis factor, essential fatty acids and dafgenes and their role in insulin resistance and non-insulin dependent diabetes mellitus. Prostaglandins Leukot Essent Fatty Acids 60: 13-20, 1999.
    • (1999) Prostaglandins Leukot Essent Fatty Acids , vol.60 , pp. 13-20
    • Das, U.N.1
  • 12
    • 0028279263 scopus 로고
    • Insulin resistance and hyperinsulinaemia: Are they secondary to an alteration in the metabolism of essential fatty acids?
    • Das UN. Insulin resistance and hyperinsulinaemia: Are they secondary to an alteration in the metabolism of essential fatty acids? Med Sci Res 22: 243-245, 1994.
    • (1994) Med Sci Res , vol.22 , pp. 243-245
    • Das, U.N.1
  • 13
    • 4444360248 scopus 로고    scopus 로고
    • N-3 long chain polyunsaturated fatty acids: A nutritional tool to prevent insulin resistance associated to type 2 diabetes and obesity?
    • Delarue J, LeFoll C, Corporeau C, and Lucas D. N-3 long chain polyunsaturated fatty acids: a nutritional tool to prevent insulin resistance associated to type 2 diabetes and obesity? Reprod Nutr Dev 44: 289-299, 2004.
    • (2004) Reprod Nutr Dev , vol.44 , pp. 289-299
    • Delarue, J.1    LeFoll, C.2    Corporeau, C.3    Lucas, D.4
  • 14
    • 0034123037 scopus 로고    scopus 로고
    • Development of hypertension in a rat model of diet-induced obesity
    • Dobrian AD, Davies MJ, Prewitt RL, and Lauterio TJ. Development of hypertension in a rat model of diet-induced obesity. Hypertension 35: 1009-1015, 2000.
    • (2000) Hypertension , vol.35 , pp. 1009-1015
    • Dobrian, A.D.1    Davies, M.J.2    Prewitt, R.L.3    Lauterio, T.J.4
  • 15
    • 1542347160 scopus 로고    scopus 로고
    • Cross-fostering to diabetic rat dams affects early development of mediobasal hypothalamic nuclei regulating food intake, body weight, and metabolism
    • Fahrenkrog S, Harder T, Stolaczyk E, Melchior K, Franke K, Dudenhausen JW, and Plagemann A. Cross-fostering to diabetic rat dams affects early development of mediobasal hypothalamic nuclei regulating food intake, body weight, and metabolism. J Nutr 134: 648-654, 2004.
    • (2004) J Nutr , vol.134 , pp. 648-654
    • Fahrenkrog, S.1    Harder, T.2    Stolaczyk, E.3    Melchior, K.4    Franke, K.5    Dudenhausen, J.W.6    Plagemann, A.7
  • 16
    • 0019205487 scopus 로고
    • Long-term effects of early nutritional experience on the development of obesity in the rat
    • Faust IM, Johnson PR, and Hirsch J. Long-term effects of early nutritional experience on the development of obesity in the rat. J Nutr 110: 2027-2034, 1980.
    • (1980) J Nutr , vol.110 , pp. 2027-2034
    • Faust, I.M.1    Johnson, P.R.2    Hirsch, J.3
  • 17
    • 0030253891 scopus 로고    scopus 로고
    • The early intracellular signaling pathway for the insulin/insulin-like growth factor receptor family in the mammalian central nervous system
    • Folli F, Ghidella S, Bonfanti L, Kahn CR, and Merighi A. The early intracellular signaling pathway for the insulin/insulin-like growth factor receptor family in the mammalian central nervous system. Mol Neurobiol 13: 155-183, 1996.
    • (1996) Mol Neurobiol , vol.13 , pp. 155-183
    • Folli, F.1    Ghidella, S.2    Bonfanti, L.3    Kahn, C.R.4    Merighi, A.5
  • 19
    • 0037474044 scopus 로고    scopus 로고
    • Postnatal development of the hypothalamic neuropeptide Y system
    • Grove KL, Allen S, Grayson BE, and Smith MS. Postnatal development of the hypothalamic neuropeptide Y system. Neuroscience 116: 393-406, 2003.
    • (2003) Neuroscience , vol.116 , pp. 393-406
    • Grove, K.L.1    Allen, S.2    Grayson, B.E.3    Smith, M.S.4
  • 20
    • 0030919789 scopus 로고    scopus 로고
    • Modifying the n-3 fatty acid content of the maternal diet to determine the requirements of the fetal and suckling rat
    • Guesnet P, Alasnier C, Alessandri JM, and Durand G. Modifying the n-3 fatty acid content of the maternal diet to determine the requirements of the fetal and suckling rat. Lipids 32: 527-534, 1997.
    • (1997) Lipids , vol.32 , pp. 527-534
    • Guesnet, P.1    Alasnier, C.2    Alessandri, J.M.3    Durand, G.4
  • 21
    • 0028899049 scopus 로고
    • High-fat feeding during pregnancy and lactation affects offspring metabolism in rats
    • Guo F and Jen KL. High-fat feeding during pregnancy and lactation affects offspring metabolism in rats. Physiol Behav 57: 681-686, 1995.
    • (1995) Physiol Behav , vol.57 , pp. 681-686
    • Guo, F.1    Jen, K.L.2
  • 22
    • 0031837952 scopus 로고    scopus 로고
    • Syndrome X-like alterations in adult female rats due to neonatal insulin treatment
    • Harder T, Plagemann A, Rohde W, and Dorner G. Syndrome X-like alterations in adult female rats due to neonatal insulin treatment. Metab Clin Exper 47: 855-862, 1998.
    • (1998) Metab Clin Exper , vol.47 , pp. 855-862
    • Harder, T.1    Plagemann, A.2    Rohde, W.3    Dorner, G.4
  • 23
    • 0015860206 scopus 로고
    • Effect of early nutrition on adipose cellularity and pancreatic insulin release in the Zucker rat
    • Johnson PR, Stern JS, Greenwood MR, Zucker LM, and Hirsch J. Effect of early nutrition on adipose cellularity and pancreatic insulin release in the Zucker rat. J Nutr 103: 738-743, 1973.
    • (1973) J Nutr , vol.103 , pp. 738-743
    • Johnson, P.R.1    Stern, J.S.2    Greenwood, M.R.3    Zucker, L.M.4    Hirsch, J.5
  • 24
    • 0024790476 scopus 로고
    • Maternal milk and plasma glucose and insulin levels: Studies in normal and diabetic subjects
    • Jovanovic-Peterson L, Fuhrmann K, Hedden K, Walker L, and Peterson CM. Maternal milk and plasma glucose and insulin levels: studies in normal and diabetic subjects. J Am Coll Nutr 8: 125-131, 1989.
    • (1989) J Am Coll Nutr , vol.8 , pp. 125-131
    • Jovanovic-Peterson, L.1    Fuhrmann, K.2    Hedden, K.3    Walker, L.4    Peterson, C.M.5
  • 25
    • 1442276966 scopus 로고    scopus 로고
    • Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons
    • Kang L, Routh VH, Kuzhikandathil EV, Gaspers L, and Levin BE. Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons. Diabetes 53: 549-559, 2004.
    • (2004) Diabetes , vol.53 , pp. 549-559
    • Kang, L.1    Routh, V.H.2    Kuzhikandathil, E.V.3    Gaspers, L.4    Levin, B.E.5
  • 26
    • 0002949909 scopus 로고
    • The development with age of hypothalamic restraint upon the appetite of the rat
    • Kennedy GC. The development with age of hypothalamic restraint upon the appetite of the rat. J Endocrinol 16: 9-17, 1957.
    • (1957) J Endocrinol , vol.16 , pp. 9-17
    • Kennedy, G.C.1
  • 28
    • 0036084856 scopus 로고    scopus 로고
    • Maternal dietary intake of essential fatty acids affects adipose tissue growth and leptin mRNA expression in suckling rat pups
    • Korotkova M, Gabrielsson B, Hanson LA, and Strandvik B. Maternal dietary intake of essential fatty acids affects adipose tissue growth and leptin mRNA expression in suckling rat pups. Pediatr Res 52: 78-84, 2002.
    • (2002) Pediatr Res , vol.52 , pp. 78-84
    • Korotkova, M.1    Gabrielsson, B.2    Hanson, L.A.3    Strandvik, B.4
  • 29
    • 0036794724 scopus 로고    scopus 로고
    • Leptin levels in rat offspring are modified by the ratio of linoleic to α-linolenic acid in the maternal diet
    • Korotkova M, Gabrielsson B, Lonn M, Hanson LA, and Strandvik B. Leptin levels in rat offspring are modified by the ratio of linoleic to α-linolenic acid in the maternal diet. J Lipid Res 43: 1743-1749, 2002.
    • (2002) J Lipid Res , vol.43 , pp. 1743-1749
    • Korotkova, M.1    Gabrielsson, B.2    Lonn, M.3    Hanson, L.A.4    Strandvik, B.5
  • 30
    • 0028072540 scopus 로고
    • Development and characterization of a purified diet to identify obesity-susceptible and resistant rat populations
    • Lauterio TJ, Bond JP, and Ulman EA. Development and characterization of a purified diet to identify obesity-susceptible and resistant rat populations. J Nutr 124: 2172-2178, 1994.
    • (1994) J Nutr , vol.124 , pp. 2172-2178
    • Lauterio, T.J.1    Bond, J.P.2    Ulman, E.A.3
  • 31
    • 0027466840 scopus 로고
    • Regulation of growth-associated protein 43 (GAP-43) messenger RNA associated with plastic change in the adult rat barrel receptor complex
    • Levin BE, and Dunn-Meynell A. Regulation of growth-associated protein 43 (GAP-43) messenger RNA associated with plastic change in the adult rat barrel receptor complex. Mol Brain Res 18: 59-70, 1993.
    • (1993) Mol Brain Res , vol.18 , pp. 59-70
    • Levin, B.E.1    Dunn-Meynell, A.2
  • 32
    • 0036838623 scopus 로고    scopus 로고
    • Maternal obesity alters adiposity and monoamine function in genetically predisposed offspring
    • Levin BE and Dunn-Meynell AA. Maternal obesity alters adiposity and monoamine function in genetically predisposed offspring. Am J Physiol Regul Integr Comp Physiol 283: R1087-R1093, 2002.
    • (2002) Am J Physiol Regul Integr Comp Physiol , vol.283
    • Levin, B.E.1    Dunn-Meynell, A.A.2
  • 34
    • 0347988175 scopus 로고    scopus 로고
    • Obesity-prone rats have normal blood-brain barrier transport but defective central leptin signaling prior to obesity onset
    • Levin BE, Dunn-Meynell AA, and Banks WA. Obesity-prone rats have normal blood-brain barrier transport but defective central leptin signaling prior to obesity onset. Am J Physiol Regul Integr Comp Physiol 286: R143-R150, 2004.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286
    • Levin, B.E.1    Dunn-Meynell, A.A.2    Banks, W.A.3
  • 36
    • 0031738244 scopus 로고    scopus 로고
    • Gestational obesity accentuates obesity in obesity-prone progeny
    • Levin BE and Govek E. Gestational obesity accentuates obesity in obesity-prone progeny. Am J Physiol Regul Integr Comp Physiol 275: R1374-R1379, 1998.
    • (1998) Am J Physiol Regul Integr Comp Physiol , vol.275
    • Levin, B.E.1    Govek, E.2
  • 37
    • 0000977522 scopus 로고
    • Plasticity of brain α-adrenoceptors during the development of diet-induced obesity in the rat
    • Levin BE and Hamm MW. Plasticity of brain α-adrenoceptors during the development of diet-induced obesity in the rat. Obes Res 2: 230-238, 1994.
    • (1994) Obes Res , vol.2 , pp. 230-238
    • Levin, B.E.1    Hamm, M.W.2
  • 39
    • 0018380614 scopus 로고
    • Catecholamine levels in discrete brain nuclei of seven month old genetically obese rats
    • Levin BE and Sullivan AC. Catecholamine levels in discrete brain nuclei of seven month old genetically obese rats. Pharmacol Biochem Behav 11: 77-82, 1979.
    • (1979) Pharmacol Biochem Behav , vol.11 , pp. 77-82
    • Levin, B.E.1    Sullivan, A.C.2
  • 40
    • 0021732102 scopus 로고
    • Neuropeptide Y: A potent inducer of consumatory behavior in rats
    • Levine AS and Morley JE. Neuropeptide Y: a potent inducer of consumatory behavior in rats. Peptides 5: 1025-1029, 1984.
    • (1984) Peptides , vol.5 , pp. 1025-1029
    • Levine, A.S.1    Morley, J.E.2
  • 41
    • 0035826876 scopus 로고    scopus 로고
    • Time course of short-term and long-term orexigenic effects of Agouti-related protein (86 -132)
    • Lu XY, Nicholson JR, Akil H, and Watson SJ. Time course of short-term and long-term orexigenic effects of Agouti-related protein (86 -132). Neuroreport 12: 1281-1284, 2001.
    • (2001) Neuroreport , vol.12 , pp. 1281-1284
    • Lu, X.Y.1    Nicholson, J.R.2    Akil, H.3    Watson, S.J.4
  • 42
    • 0032821965 scopus 로고    scopus 로고
    • Insulin sensitivity indices obtained from oral glucose tolerance testing: Comparison with the euglycemic insulin clamp
    • Matsuda M and DeFronzo R. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 22: 1462-1470, 1999.
    • (1999) Diabetes Care , vol.22 , pp. 1462-1470
    • Matsuda, M.1    DeFronzo, R.2
  • 43
    • 0034928759 scopus 로고    scopus 로고
    • Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations
    • Meaney MJ. Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. Annu Rev Neurosci 24: 1161-1192, 2003.
    • (2003) Annu Rev Neurosci , vol.24 , pp. 1161-1192
    • Meaney, M.J.1
  • 44
    • 6344277183 scopus 로고    scopus 로고
    • Variations of maternal care differentially influence 'fear' reactivity and regional patterns of cFos immunoreactivity in response to the shock-probe burying test
    • Menard JL, Champagne DL, and Meaney MJ. Variations of maternal care differentially influence 'fear' reactivity and regional patterns of cFos immunoreactivity in response to the shock-probe burying test. Neuroscience 129: 297-308, 2004.
    • (2004) Neuroscience , vol.129 , pp. 297-308
    • Menard, J.L.1    Champagne, D.L.2    Meaney, M.J.3
  • 46
    • 30044447631 scopus 로고    scopus 로고
    • Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons
    • Morton GJ, Gelling RW, Niswender KD, Morrison CD, Rhodes CJ, and Schwartz MW. Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons. Cell Metab 2: 411-420, 2005.
    • (2005) Cell Metab , vol.2 , pp. 411-420
    • Morton, G.J.1    Gelling, R.W.2    Niswender, K.D.3    Morrison, C.D.4    Rhodes, C.J.5    Schwartz, M.W.6
  • 48
    • 0015697938 scopus 로고
    • Isolated removal of hypothalamic or other brain nuclei of the rat
    • Palkovits M. Isolated removal of hypothalamic or other brain nuclei of the rat. Brain Res 59: 449-450, 1973.
    • (1973) Brain Res , vol.59 , pp. 449-450
    • Palkovits, M.1
  • 50
    • 0033018753 scopus 로고    scopus 로고
    • Morphological alterations of hypothalamic nuclei due to intrahypothalamic hyperinsulinemia in newborn rats
    • Plagemann A, Harder T, Rake A, Janert U, Melchior K, Rohde W, and Dorner G. Morphological alterations of hypothalamic nuclei due to intrahypothalamic hyperinsulinemia in newborn rats. Int J Dev Neurosci 17: 37-44, 1999.
    • (1999) Int J Dev Neurosci , vol.17 , pp. 37-44
    • Plagemann, A.1    Harder, T.2    Rake, A.3    Janert, U.4    Melchior, K.5    Rohde, W.6    Dorner, G.7
  • 51
    • 0033787384 scopus 로고    scopus 로고
    • Maternal environment and genotype interact to establish diabesity in mice
    • Reifsnyder PC, Churchill G, and Leiter EH. Maternal environment and genotype interact to establish diabesity in mice. Genome Res 10: 1568-1578, 2000.
    • (2000) Genome Res , vol.10 , pp. 1568-1578
    • Reifsnyder, P.C.1    Churchill, G.2    Leiter, E.H.3
  • 52
    • 0041919296 scopus 로고    scopus 로고
    • Ontogeny of diet-Induced obesity in selectivelybred Sprague-Dawley rats
    • Ricci MR and Levin BE. Ontogeny of diet-Induced obesity in selectivelybred Sprague-Dawley rats. Am J Physiol Regul Integr Comp Physiol 285: R610-R618, 2003.
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.285
    • Ricci, M.R.1    Levin, B.E.2
  • 53
    • 0035479567 scopus 로고    scopus 로고
    • Postnatal development of catecholamine inputs to the paraventricular nucleus of the hypothalamus in rats
    • Rinaman L. Postnatal development of catecholamine inputs to the paraventricular nucleus of the hypothalamus in rats. J Comp Neurol 438: 411-422, 2001.
    • (2001) J Comp Neurol , vol.438 , pp. 411-422
    • Rinaman, L.1
  • 54
    • 0038381461 scopus 로고    scopus 로고
    • Postnatal development of hypothalamic inputs to the dorsal vagal complex in rats
    • Rinaman L. Postnatal development of hypothalamic inputs to the dorsal vagal complex in rats. Physiol Behav 79: 65-70, 2003.
    • (2003) Physiol Behav , vol.79 , pp. 65-70
    • Rinaman, L.1
  • 55
    • 0022549972 scopus 로고
    • Lactation in lean and obese rats: Effect of cafeteria feeding and of dietary obesity on milk composition
    • Rolls BA, Gurr MI, van Duijvenvoorde PM, Rolls BJ, and Rowe EA. Lactation in lean and obese rats: effect of cafeteria feeding and of dietary obesity on milk composition. Physiol Behav 38: 185-190, 1986.
    • (1986) Physiol Behav , vol.38 , pp. 185-190
    • Rolls, B.A.1    Gurr, M.I.2    Van Duijvenvoorde, P.M.3    Rolls, B.J.4    Rowe, E.A.5
  • 56
    • 22744446857 scopus 로고    scopus 로고
    • Differential effects of dietary saturated and trans-fatty acids on expression of genes associated with insulin sensitivity in rat adipose tissue
    • Saravanan N, Haseeb A, Ehtesham NZ, and Ghafoorunissa. Differential effects of dietary saturated and trans-fatty acids on expression of genes associated with insulin sensitivity in rat adipose tissue. Eur J Endocrinol 153: 159-165, 2005.
    • (2005) Eur J Endocrinol , vol.153 , pp. 159-165
    • Saravanan, N.1    Haseeb, A.2    Ehtesham, N.Z.3    Ghafoorunissa4
  • 57
    • 44949263977 scopus 로고    scopus 로고
    • Longchain polyunsaturated fatty acid supplementation in preterm infants
    • CD000375
    • Simmer K and Patole S. Longchain polyunsaturated fatty acid supplementation in preterm infants. Cochrane Database Syst Rev: CD000375, 2004.
    • (2004) Cochrane Database Syst Rev
    • Simmer, K.1    Patole, S.2
  • 58
    • 17244377113 scopus 로고    scopus 로고
    • Essential fatty acids, DHA and human brain
    • Singh M. Essential fatty acids, DHA and human brain. Indian J Pediatr 72: 239-242, 2005.
    • (2005) Indian J Pediatr , vol.72 , pp. 239-242
    • Singh, M.1
  • 59
    • 0036738829 scopus 로고    scopus 로고
    • Stimulation of peroxisome proliferator-activated receptors alpha and gamma blocks HIV-1 replication and TNFα production in acutely infected primary blood cells, chronically infected U1 cells, and alveolar macrophages from HIV-infected subjects
    • Skolnik PR, Rabbi MF, Mathys JM, and Greenberg AS. Stimulation of peroxisome proliferator-activated receptors alpha and gamma blocks HIV-1 replication and TNFα production in acutely infected primary blood cells, chronically infected U1 cells, and alveolar macrophages from HIV-infected subjects. J Acquir Immune Defic Syndr Hum Retrovirol 31: 1-10, 2002.
    • (2002) J Acquir Immune Defic Syndr Hum Retrovirol , vol.31 , pp. 1-10
    • Skolnik, P.R.1    Rabbi, M.F.2    Mathys, J.M.3    Greenberg, A.S.4
  • 60
    • 27744457512 scopus 로고    scopus 로고
    • Topographic mapping of VMH → arcuate nucleus microcircuits and their reorganization by fasting
    • Sternson SM, Shepherd GMG, and Friedman JM. Topographic mapping of VMH → arcuate nucleus microcircuits and their reorganization by fasting. Nat Neurosci 8: 1356-1363, 2005.
    • (2005) Nat Neurosci , vol.8 , pp. 1356-1363
    • Sternson, S.M.1    Gmg, S.2    Friedman, J.M.3
  • 61
    • 0025334309 scopus 로고
    • Trophic effects of insulin-like growth factor-I on fetal rat hypothalamic cells in culture
    • Torres-Aleman I, Naftolin F, and Robbins RJ. Trophic effects of insulin-like growth factor-I on fetal rat hypothalamic cells in culture. Neuroscience 35: 601-608, 1990.
    • (1990) Neuroscience , vol.35 , pp. 601-608
    • Torres-Aleman, I.1    Naftolin, F.2    Robbins, R.J.3
  • 64
    • 0036179718 scopus 로고    scopus 로고
    • Dietary essential fatty acids and brain function: A developmental perspective on mechanisms
    • Wainwright PE. Dietary essential fatty acids and brain function: a developmental perspective on mechanisms. Proc Nutr Soc 61: 61-69, 2002.
    • (2002) Proc Nutr Soc , vol.61 , pp. 61-69
    • Wainwright, P.E.1
  • 65
    • 0036088134 scopus 로고    scopus 로고
    • Effects of dietary fat types on body fatness, leptin, and ARC leptin receptor, NPY, and AgRP mRNA expression
    • Wang H, Storlien LH, and Huang XF. Effects of dietary fat types on body fatness, leptin, and ARC leptin receptor, NPY, and AgRP mRNA expression. Am J Physiol Endocrinol Metab 282: E1352-E1359, 2002.
    • (2002) Am J Physiol Endocrinol Metab , vol.282
    • Wang, H.1    Storlien, L.H.2    Huang, X.F.3
  • 66
    • 3242765290 scopus 로고    scopus 로고
    • The regulation of glucose-excited (GE) neurons in the hypothalamic arcuate nucleus by glucose and feeding relevant peptides
    • Wang R, Liu X, Dunn-Meynell AA, Levin BE, and Routh VH. The regulation of glucose-excited (GE) neurons in the hypothalamic arcuate nucleus by glucose and feeding relevant peptides. Diabetes 53: 1959-1965, 2004.
    • (2004) Diabetes , vol.53 , pp. 1959-1965
    • Wang, R.1    Liu, X.2    Dunn-Meynell, A.A.3    Levin, B.E.4    Routh, V.H.5
  • 67
    • 0036678588 scopus 로고    scopus 로고
    • Maternal behavior regulates long-term hippocampal expression of BAX and apoptosis in the offspring
    • Weaver IC, Grant RJ, and Meaney MJ. Maternal behavior regulates long-term hippocampal expression of BAX and apoptosis in the offspring. J Neurochem 82: 998-1002, 2002.
    • (2002) J Neurochem , vol.82 , pp. 998-1002
    • Weaver, I.C.1    Grant, R.J.2    Meaney, M.J.3
  • 69
    • 0023746608 scopus 로고
    • Projection of pro-opiomelanocortin neurons from the rat arcuate nucleus to the midbrain central gray as demonstrated by double staining with retrograde labeling and immunocytochemistry
    • Yoshida M and Taniguchi Y. Projection of pro-opiomelanocortin neurons from the rat arcuate nucleus to the midbrain central gray as demonstrated by double staining with retrograde labeling and immunocytochemistry. Arch Histol Cytol 51: 175-183, 1988.
    • (1988) Arch Histol Cytol , vol.51 , pp. 175-183
    • Yoshida, M.1    Taniguchi, Y.2
  • 70
    • 0033695523 scopus 로고    scopus 로고
    • Differential expression of hypothalamic neuropeptides in the early phase of diet-induced obesity in mice
    • Ziotopoulou M, Mantzoros CS, Hileman SM, and Flier JS. Differential expression of hypothalamic neuropeptides in the early phase of diet-induced obesity in mice. Am J Physiol Endocrinol Metab 279: E838-E845, 2000.
    • (2000) Am J Physiol Endocrinol Metab , vol.279
    • Ziotopoulou, M.1    Mantzoros, C.S.2    Hileman, S.M.3    Flier, J.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.