Cytostatic and antiviral 6-arylpurine ribonucleosides. Part 7: Synthesis and evaluation of 6-substituted purine l-ribonucleosides

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 20, 2006, Pages 5290-5293

  Hocek, Michal ^a   Šilhár, Peter ^a   Shih, I hung ^b   Mabery, Eric ^b   Mackman, Richard ^b  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^b GILEAD SCIENCES   (United States)

Author keywords

Antivirals; HCV; Nucleosides; Purines

Indexed keywords

6 CHLORO 9 (2,3,5 TRI O ACETYL BETA LEVO RIBOFURANOSYL)PURINE; PALLADIUM; PURINE DERIVATIVE; RIBONUCLEOSIDE DERIVATIVE; RNA POLYMERASE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CATALYSIS; CROSS COUPLING REACTION; CYTOSTASIS; DEPROTECTION REACTION; DRUG SYNTHESIS; ENANTIOMER; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; NONHUMAN; REPLICON;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIVIRAL AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HEPACIVIRUS; HL-60 CELLS; HUMANS; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PURINE NUCLEOSIDES; RIBONUCLEOSIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

HEPATITIS C VIRUS;

EID: 33748316499     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.07.092     Document Type: Article

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