Cytostatic 6-arylpurine nucleosides. 6. SAR in anti-HCV and cytostatic activity of extended series of 6-hetarylpurine ribonucleosides

Journal of Medicinal Chemistry

Volumn 48, Issue 18, 2005, Pages 5869-5873

  Hocek, Michal ^a   Nauš, Petr ^a   Pohl, Radek ^a   Votruba, Ivan ^a   Furman, Phillip A ^b   Tharnish, Phillip M ^b   Otto, Michael J ^b  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^b PHARMASSET INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 (1H PYRROL 3 YL) 9 (BETA DEXTRO RIBOFURANOSYL)PURINE; 6 CHLOROPURINE NUCLEOSIDE DERIVATIVE; ANTIVIRUS AGENT; BORONIC ACID DERIVATIVE; CYTOSTATIC AGENT; HALIDE; NUCLEOSIDE DERIVATIVE; PURINE NUCLEOSIDE; UNCLASSIFIED DRUG; ZINC HALIDE;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CROSS COUPLING REACTION; CYTOSTASIS; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; HEPATITIS C VIRUS; HUMAN; HUMAN CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIVIRAL AGENTS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HEPACIVIRUS; HUMANS; MICE; PURINE NUCLEOSIDES; RIBONUCLEOSIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 24744436849     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm050335x     Document Type: Article

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