Research on L-Nucleosides. Synthesis and biological evaluation of a series of L- and D-2′,3′-Dideoxy-3′-[tris(methylthio)methyl]-β- pentofuranosyl nucleosides

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 3, 2003, Pages 357-366

  Mugnaini, Claudia ^a   Botta, Maurizio ^a   Coletta, Massimo ^b   Corelli, Federico ^a   Focher, Federico ^c   Marini, Stefano ^b   Renzulli, Michela Lucia ^a   Verri, Annalisa ^c  

^a UNIVERSITY OF SIENA   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2',3' DIDEOXY 3' C TRIS(METHYLTHIO)METHYL BETA DEXTRO ERYTHRO PENTOFURANOSYL] 5 FLUOROURACIL; 1 [2',3' DIDEOXY 3' C TRIS(METHYLTHIO)METHYL BETA DEXTRO ERYTHRO PENTOFURANOSYL]CYTOSINE; 1 [2',3' DIDEOXY 3' C TRIS(METHYLTHIO)METHYL BETA DEXTRO ERYTHRO PENTOFURANOSYL]THYMINE; 1 [2',3' DIDEOXY 3' C TRIS(METHYLTHIO)METHYL BETA DEXTRO ERYTHRO PENTOFURANOSYL]URACIL; 1 [2',3' DIDEOXY 3' C TRIS(METHYLTHIO)METHYL BETA LEVO ERYTHRO PENTOFURANOSYL] 5 FLUOROURACIL; 1 [2',3' DIDEOXY 3' C TRIS(METHYLTHIO)METHYL BETA LEVO ERYTHRO PENTOFURANOSYL]CYTOSINE; 1 [2',3' DIDEOXY 3' C TRIS(METHYLTHIO)METHYL BETA LEVO ERYTHRO PENTOFURANOSYL]THYMINE; 1 [2',3' DIDEOXY 3' C TRIS(METHYLTHIO)METHYL BETA LEVO ERYTHRO PENTOFURANOSYL]URACIL; METHYL GROUP; NUCLEOSIDE DERIVATIVE; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; ENANTIOMER; IC 50; LIPOPHILICITY; MEDICAL RESEARCH; MOLECULE; MOUSE; NONHUMAN; PHOSPHORYLATION; STEREOCHEMISTRY;

3T3 CELLS; ANIMALS; ANTIVIRAL AGENTS; ENZYME INHIBITORS; FURANS; HERPESVIRUS 1, HUMAN; INHIBITORY CONCENTRATION 50; MICE; NUCLEOSIDES; PHOSPHORYLATION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THYMIDINE KINASE; TUMOR CELLS, CULTURED;

HUMAN HERPESVIRUS 1;

EID: 0037293520     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(02)00460-1     Document Type: Article

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