Ex vivo culture of Fancc-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy

Blood

Volumn 105, Issue 9, 2005, Pages 3465-3471

  Li, Xiaxin ^b   Le Beau, Michelle M ^b   Ciccone, Samantha ^b   Yang, Feng Chun ^b   Freie, Brian ^b   Chen, Shi ^b   Yuan, Jin ^b   Hong, Ping ^b   Orazi, Attilio ^b   Haneline, Laura S ^b   Clapp, D Wade ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE MARROW CANCER; BONE MARROW CELL; CANCER RISK; CELL CULTURE; CELL PROLIFERATION; CELL SURVIVAL; CHROMOSOME ABERRATION; CLONE; CONTROLLED STUDY; FANCONI ANEMIA; GENE THERAPY; GENOMIC INSTABILITY; HEMATOLOGIC MALIGNANCY; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; INCIDENCE; MOLONEY LEUKEMIA ONCOVIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS; STEM CELL; TRANSGENE; WILD TYPE;

EID: 20944451595     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-06-2483     Document Type: Article

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