Transforming growth factor-β1 is a mediator of androgen-regulated growth arrest in an androgen-responsive prostatic cancer cell line, LNCaP

Endocrinology

Volumn 137, Issue 3, 1996, Pages 991-999

  Kim, Isaac Yi ^a   Kim, Jin Ho ^a   Zelner, David J ^a   Ahn, Han Jong ^a,b   Sensibar, Julia A ^a   Lee, Chung ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b University of Ulsan College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTANOLONE; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; GROWTH INHIBITION; GROWTH REGULATION; HORMONAL REGULATION; HORMONE RESPONSE; HUMAN; HUMAN CELL; IMMUNOMODULATION; PRIORITY JOURNAL; PROSTATE CANCER;

EID: 0029671462     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.3.8603613     Document Type: Article

References (38)

1. Horoszewicz JS, Leong SS, Kawinski E, Karr JP, Rosenthal H, Chu MT, Mirand EA, Murphy GP 1983 LNCaP model of human prostatic carcinoma. Cancer Res 43:1808-1817
2. Wilding G, Chen M, Gelmann E 1989 Aberrant response in vitro of hormone-responsive prostate cancer cells to anti-androgens. Prostate 14:103-115
3. Kokontis J, Kiyoshi I, Hiipakka RA, Liao S 1991 Expression and function of normal and LNCaP androgen receptors in androgen-insensitive human prostatic cancer cells. Altered hormone and antihormone specificity in gene transactivation. Receptor 1:271-270
4. Veldscholte J, Ris-Staplers C, Kuiper GGJM, Jenster G, Berrevoets C, Classen E, van Fooij HCJ, Trapman J, Brinkman AO, Muler E 1990 A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens. Biochem Biophys Res Commun 173:534-540
5. Taplin ME, Bubley GJ, Shuster TD, Frantz ME, Spooner AE, Ogata GK, Keer HN, Balk SP 1995 Mutation of the androgen receptor gene in metastatic androgen-independent prostate cancer. New Engl J Med 332:1393-1398
6. Sonnenschein C, Olea N, Pasanen ME, Soto AM 1989 Negative controls of cell proliferation: human prostate cancer cells and androgens. Cancer Res 49:3474-3481
7. Schuurmans ALG, Bolt J, Mulder E 1988 Androgens stimulate both the growth rate and epidermal growth factor receptor activity of the human prostate tumor cell line LNCaP. Prostate 12:55-64
8. Lee C, Sutkowski DM, Sensibar JA, Zelner D, Kim I, Amsel I, Shaw N, Prins GS, Kozlowski JM 1995 Regulation of proliferation and production of prostate specific antigen in androgen-sensitive prostatic cancer cells, LNCaP, by dihydrotestosterone. Endocrinology 136:796-803
9. Davies P, Eaton CL 1991 Regulation of prostate growth. J Endocrinol 131:5-17
10. Wilding G 1991 Response of prostate cancer cells to peptide growth factors: transforming growth factor-β. Cancer Surv 11:147-163
11. Derynck R, Jarret JA, Chen EY, Eaton DH, Bell JR, Assoian RK, Roberts AB, Sporn MB, Goeddel DV 1985 Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells. Nature 316:701-705
12. Madison L, Webb NR, Rose TM, Marquardt H, Ikeda T, Twardzik D, Seyedin S, Purchio AF 1988 Transforming growth factor-beta 2: cDNA cloning and sequence analysis. DNA 7:1-8
13. Jakowlew SB, Dillard PJ, Kondaiah P, Sporn MB, Roberts AB 1988 Complementary deoxyribonucleic acid cloning of a novel transforming growth factor-beta messenger ribonucleic acid from chick embryo chondrocytes. Mol Endocrinol 2:747-755
14. Jakowlew SB, Dillard PJ, Sporn MB, Roberts AB 1988 Complementary deoxyribonucleic acid cloning of a messenger ribonucleic acid encoding transforming growth factor beta 4 from chicken embryo chondrocytes. Mol Endocrinol 2:1186-1195
15. Kondaiah P, Sands MJ, Smith JM, Fields A, Roberts AB, Sporn MB, Melton DA 1990 Identification of a novel transforming growth factor-beta (TGF-beta 5) mRNA in Xenopus laevis. J Biol Chem 265:1089-1093
16. Knabbe C, Lippman ME, Wakefield DM, Flanders KC, Kasid A, Derynck R, Dickinson RB 1987 Evidence that transforming growth factor beta is a hormonally regulated negative growth factor in human breast cancer cells. Cell 48:417-428
17. Kyprianou N, Isaacs JT 1989 Expression of transforming growth factor beta in the rat ventral prostate during castration induced programmed cell death. Mol Endocrinol 3:1515-1522
18. Kyprianou N, Isaacs JT 1988 Identification of a cellular receptor for transforming growth factor-β in rat ventral prostate and its negative regulation by androgens. Endocrinology 123:2124-2132
19. Martikainen P, Kyprianou N, Isaacs JT 1990 Effect of transforming growth factor-β1 on proliferation and death of rat prostatic cells. Endocrinology 127:2963-2968
20. Sutkowski DM, Fong CJ, Sansibar JA, Rademaker AW, Sherwood ER, Kozlowski JM, Lee C 1992 Interaction of epidermal growth factor and transforming growth factor beta in human prostatic epithelial cells in culture. Prostate 21:133-143
21. Wilding G, Zugmeier G, Knabbe C, Flanders K, Gelmann E 1989 Differential effects of transforming growth factor β on human prostate cancer cells in vitro. Mol Cell Endocrinol 62:79-87
22. Franzen P, Ichijo H, Miyazono K 1993 Different signals mediate transforming growth factor-β1-induced growth inhibition and extracellular matrix production in prostatic carcinoma cells. Exp Cell Res 207:1-7
23. Carruba G, Leake RE, Rinaldi F, Chalmers D, Comito L, Sorci C, Pavon-Macaluso M, Castagnetta LAM 1994 Steroid-growth factor interaction in human prostate cancer. 1. Short-term effects of transforming growth factors on growth of human prostate cancer cell. Steroids 59:412-420
24. Schuurmans ALG, Bolt J, Veldscholte J, Mulder E 1991 Regulation of growth of LNCaP human prostate tumor cells by growth factors and steroid hormones. J Steroid Biochem Mol Biol 40:193-197
25. Siebert PD, Larrick JW 1992 Competitive PCR. Nature 359:557-558
26. Forster E 1994 Rapid generation of internal standards for competitive PCR by low-stringency primer annealing. Biotechniques 16: 1006-1008
27. Fort P, Marty L, Piechaczyk M, el Sabrouty S, Dani C, Jeanteur P, Blanchard JM 1985 Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate dehydrogenase multigenic family. Nucleic Acids Res 13:1431-1442
28. Steele RED, Torrie JH 1960 Principles, procedures of statistics. McGraw-Hill Book Company, Inc., New York, pp 99-131
29. Miyazono K, Olofsson A, Colosetti P, Heldin C-H 1991 A role of the latent TGF-β1-binding protein in the assembly and secretion of TGF-β1. EMBO J 10:1091-1101
30. Lawrence DA, Pircher R, Jullien P 1985 Conversion of a high molecular weight latent beta-TGF from chicken embryo fibroblasts into a low molecular weight active beta-TGF under acidic conditions. Biochem Biophys Res Commun 133:1026-1034
31. Lyons RM, Keski-Oja J, Moses HL 1988 Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium. J Cell Biol 106:1659-1665
32. Wakefield LM, Smith DM, Masui T, Harris CC, Sporn MB 1987 Distribution and modulation of the cellular receptors for transform-ing growth factor-beta. J Cell Biol 105:965-975
33. Massague J, Cheifetz S, Laiho M, Ralph DA, Weis FMB, Zentella A 1992 Transforming growth factor-β. Cancer Surv 12:81-103
34. Dennis PA, Rifkin DB 1991 Cellular activation of latent transforming growth factor β requires binding to the cation-independent mannose-6-phosphate/insulin-like growth factor type II receptor. Proc Natl Acad Sci USA 88:580-584
35. Schuurmans ALG, Bolt J, Voorhorst MM, Blankenstein RA, Mulder E 1988 Regulation of growth and epidermal growth factor receptor levels of LNCaP prostate tumor cells by different steroids. Int J Cancer 42:917-922
36. Kassen A, Kozlowski JM, Lee C, Role of basic fibroblast growth factor in autocrine regulation of LNCaP proliferation induced by dihydrotestosterone. Program of the 77th Annual Meeting of The Endocrine Society, Washington DC, 1995, p 272 (Abstract 1-639)
37. Gospodarowicz D, Ferrara N, Schweigerer L, Neufeld G 1987 Structural characterization and biological functions of basic fibroblast growth factor. Endocr Rev 8:95-114
38. Pepper MS, Delin D, Montesano R, Orci L, Vassalli JD 1990 Transforming growth factor beta 1 modulates basic fibroblast growth factor-induced proteolytic and angiogenic properties of endothelial cells in vitro. J Cell Biol 111:743-755