The relationship between conservation, thermodynamic stability, and function in the SH3 domain hydrophobic core

Journal of Molecular Biology

Volumn 333, Issue 3, 2003, Pages 641-655

  Di Nardo, Ariel A ^a,c   Larson, Stefan M ^a,b   Davidson, Alan R ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b STANFORD UNIVERSITY   (United States)

^c ECOLE NORMALE SUPÉRIEURE   (France)

Author keywords

Conservation; Hydrophobic core; Protein stability; Sequence alignment; SH3 domain

Indexed keywords

MUTANT PROTEIN; PEPTIDE; PROTEIN TYROSINE KINASE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CHEMICAL REACTION KINETICS; CORRELATION ANALYSIS; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STABILITY; THERMODYNAMICS;

EID: 0141750578     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2003.08.035     Document Type: Article

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