Total synthesis and structural confirmation of chlorodysinosin A

Journal of the American Chemical Society

Volumn 128, Issue 32, 2006, Pages 10491-10495

  Hanessian, Stephen ^a   Del Valle, Juan R ^a   Xue, Yafeng ^b   Blomberg, Niklas ^b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLOMERATION; CRYSTAL ATOMIC STRUCTURE; ENZYME INHIBITION; METABOLITES; SYNTHESIS (CHEMICAL); X RAY ANALYSIS;

CHLORODYSINOSIN A; STEREOCONTROLLED SYNTHESIS;

STEREOCHEMISTRY;

BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 7A; CHLORODYSINOSIN A; DYSINOSIN A; LEUCINE; SERINE PROTEINASE INHIBITOR; THROMBIN; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CRYSTAL STRUCTURE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEREOCHEMISTRY; STRUCTURE ANALYSIS; THROMBOCYTE AGGREGATION; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; INDOLES; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PYRROLES; SERINE ENDOPEPTIDASES; STEREOISOMERISM; THROMBIN;

EID: 33747596469     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0625834     Document Type: Article

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