Selective inhibitors of bacterial DNA adenine methyltransferases

Journal of Biomolecular Screening

Volumn 11, Issue 5, 2006, Pages 497-510

  Mashhoon, Neda ^a   Pruss, Cynthia ^a   Carroll, Michael ^a   Johnson, Paul H ^a   Reich, Norbert O ^b  

^a Pacific Technology Center   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Binding assays; Cell cycle regulated methyltransferase; DNA adenine methyltransferase; Inhibitors

Indexed keywords

CYCLOPENTAQUINOLINE CARBOXYLIC ACID; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA ADENINE METHYLTRANSFERASE; DNA METHYLTRANSFERASE 1; DNA TOPOISOMERASE; ENDONUCLEASE; ENZYME INHIBITOR; FURAN DERIVATIVE; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE; QUINOLINE DERIVATIVE; SINEFUNGIN; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL VIRULENCE; CAULOBACTER CRESCENTUS; CELL VIABILITY; DNA METHYLATION; DRUG CYTOTOXICITY; DRUG DNA BINDING; DRUG MECHANISM; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; ENZYME PURIFICATION; ESCHERICHIA COLI; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIGH THROUGHPUT SCREENING; IC 50; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION;

DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA, BACTERIAL; DNA-BINDING PROTEINS; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, BIOLOGICAL; SITE-SPECIFIC DNA-METHYLTRANSFERASE (ADENINE-SPECIFIC); STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 33747098537     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057106287933     Document Type: Article

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