DNA adenine methylase is essential for viability and plays a role in the pathogenesis of Yersinia pseudotuberculosis and Vibrio cholerae

Infection and Immunity

Volumn 69, Issue 12, 2001, Pages 7610-7615

  Julio, S M ^a   Heithoff, D M ^a   Provenzano, D ^a   Klose, K E ^a   Sinsheimer, R L ^a   Low, D A ^a   Mahan, M J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; BACTERIAL VACCINE; DNA METHYLTRANSFERASE;

ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; CHOLERA; ENZYME ACTIVITY; ENZYME SYNTHESIS; GASTROENTERITIS; GENE DISRUPTION; IMMUNE RESPONSE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SURVIVAL; VACCINATION; VIBRIO CHOLERAE; YERSINIA PSEUDOTUBERCULOSIS;

ANIMALS; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL VACCINES; CHOLERA; CHOLERA VACCINES; GENE EXPRESSION REGULATION, BACTERIAL; MICE; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; SITE-SPECIFIC DNA-METHYLTRANSFERASE (ADENINE-SPECIFIC); VIBRIO CHOLERAE; YERSINIA PSEUDOTUBERCULOSIS; YERSINIA PSEUDOTUBERCULOSIS INFECTIONS;

EID: 0035179775     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.12.7610-7615.2001     Document Type: Article

References (44)

1. The DNA adenine methyltransferase encoding gene (dam) of Vibrio cholerae
2. The complete genome sequence of Escherichia coli K-12
3. Methylation patterns in pap regulatory DNA control pyelonephritis-associated pili phase variation in E. coli
4. Methylation-related epigenetic signals in bacterial DNA
5. Differential patterns of acquired virulence genes distinguish Salmonella strains
6. The virulence plasmid of Yersinia, an antihost genome
7. Phosphorylation of the flagellar regulatory protein FlRC is necessary for Vibrio cholerae motility and enhanced colonization
8. Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector
9. Epidemiology, genetics, and ecology of toxigenic Vibrio cholerae
10. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd
11. Molecular cloning and expression of calcium-regulated, plasmid-coded proteins of Y. pseudotuberculosis
12. DNA adenine methylase mutants of Salmonella typhimurium show defects in protein secretion, cell invasion, and M cell cytotoxicity
13. Recognition sequence of the dam methylase of Escherichia coli K12 and mode of cleavage of Dpn I endonuclease
14. Induced mutagenesis in dam mutants of Escherichia coli: A role for 6-methyladenine residues in mutation avoidance
15. Protein tyrosine phosphatase activity of an essential virulence determinant in Yersinia
16. The YopB protein of Yersinia pseudotuberculosis is essential for the translocation of Yop effector proteins across the target cell plasma membrane and displays a contact-dependent membrane disrupting activity
17. Analysis of nonmethylated GATC sites in the Escherichia coli chromosome and identification of sites that are differentially methylated in response to environmental stimuli
18. Bacterial infection as assessed by in vivo gene expression
19. Salmonella DNA adenine methylase mutants confer cross-protective immunity
20. An essential role for DNA adenine methylation in bacterial virulence
21. Mammalian methyltransferases and methylCpG-binding domains: Proteins involved in DNA methylation
22. Directed formation of chromosomal deletions in Salmonella typhimurium: Targeting of specific genes induced during infection
23. The CcrM DNA methyltransferase of Agrobacterium tumefaciens is essential, and its activity is cell cycle regulated
24. Roles of DNA methylation in regulating bacterial gene expression and virulence
25. Assessment of bacterial pathogenesis by analysis of gene expression in the host
26. DNA methylation regulates bacterial gene expression and virulence
27. Selection of bacterial virulence genes that are specifically induced in host tissues
28. Methylation of DNA, edition VIII
29. Correlation of DNA adenine methylase activity with spontaneous mutability in Escherichia coli K-12
30. Yersinia-induced apoptosis in vivo aids in the establishment of a systemic infection of mice
31. YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF-alpha production and downregulation of the MAP kinases p38 and JNK
32. Cell-surface-bound Yersinia translocate the protein tyrosine phosphatase YopH by a polarized mechanism into the target cell
33. Bacterial DNA methylation: A cell cycle regulator?
34. The CtrA response regulator mediates temporal control of gene expression during the Caulobacter cell cycle
35. The Brucella abortus CcrM DNA methyltransferase is essential for viability, and its overexpression attenuates intracellular replication in murine macrophages
36. Inhibition of phagocytosis in Yersinia pseudotuberculosis: A virulence plasmid-encoded ability involving the Yop2b protein
37. The cytotoxic protein YopE of Yersinia obstructs the primary host defence
38. Target cell contact triggers expression and polarized transfer of Yersinia YopE cytotoxin into mammalian cells
39. A cell cycleregulated bacterial DNA methyltransferase is essential for viability
40. Regulation by Ca2+ in the Yersinia low-Ca2+ response
41. Quantitative whole-genome analysis of DNA-protein interactions by in vivo methylase protection in E. coli
42. Epigenetic phase variation of the pap operon in Escherichia coli
43. Construction of versatile low-copy number vectors for cloning, sequencing and gene expression in Escherichia coli
44. The CcrM DNA methyl-transferase is widespread in the alpha subdivision of proteobacteria, and its essential functions are conserved in Rhizobium meliloti and Caulobacter crescentus