Recombinant human DNA (cytosine-5) methyltransferase. II. Steady-state kinetics reveal allosteric activation by methylated DNA

Journal of Biological Chemistry

Volumn 274, Issue 46, 1999, Pages 33011-33019

  Bacolla, Albino ^a   Pradhan, Sriharsa ^b   Roberts, Richard J ^b   Wells, Robert D ^a  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^b NEW ENGLAND BIOLABS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA METHYLTRANSFERASE; PLASMID DNA; POLYPEPTIDE; RECOMBINANT ENZYME; RIBONUCLEOPROTEIN; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE;

ARTICLE; BINDING SITE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DNA METHYLATION; DNA TEMPLATE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME KINETICS; HUMAN; MATHEMATICAL ANALYSIS; PRIORITY JOURNAL;

ALLOSTERIC REGULATION; BINDING SITES; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA, SUPERHELICAL; DNA-BINDING PROTEINS; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; KINETICS; OLIGODEOXYRIBONUCLEOTIDES; RECOMBINANT PROTEINS; RIBONUCLEOPROTEINS, SMALL NUCLEAR; S-ADENOSYLHOMOCYSTEINE; S-ADENOSYLMETHIONINE; TRINUCLEOTIDE REPEATS;

EID: 0032731355     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.46.33011     Document Type: Article

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