Downregulation of clusterin expression in testicular germ cell tumours

Pathobiology

Volumn 69, Issue 1, 2001, Pages 19-23

  Behrens, P ^a   Jeske, W ^a   Wernert, N ^a   Wellmann, Axel ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

Carcinogenesis; Clusterin; Germ cell tumours

Indexed keywords

CLUSTERIN;

ARTICLE; CARCINOGENESIS; CELL MATURATION; CELL TRANSFORMATION; CHORIOCARCINOMA; CONTROLLED STUDY; EMBRYONAL CARCINOMA; GERM CELL TUMOR; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LEYDIG CELL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEMINOMA; TERATOMA; TESTIS; YOLK SAC TUMOR;

BIOLOGICAL MARKERS; CLUSTERIN; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GERMINOMA; GLYCOPROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MOLECULAR CHAPERONES; TESTICULAR NEOPLASMS;

EID: 0034779990     PISSN: 10152008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000048753     Document Type: Article

References (33)

1. Apolipoprotein J: Structure and tissue distribution
2. Circulating and luminal testicular factors affect LRP-2 and Apo J expression in the epididymis following efferent duct ligation
3. Functional and structural properties of lipid-associated apolipoprotein (clusterin)
4. Ram rete testis fluid contains a protein (clusterin) which influences cell-cell interactions in vitro
5. Stallion epididymal fluid proteome: Qualitative and quantitative characterization; secretion and dynamic changes of major proteins
6. Human clusterin (CLI) maps to 8p21 in proximity to the lipoprotein lipase (LPL) gene
7. Molecular characterization of human TRPM-2/clusterin, a gene associated with sperm maturation, apoptosis and neurodegeneration
8. Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: Identity to sulfated glycoprotein 2, a constituent of rat testis fluid
9. Expression and regulation of LRP-2/megalin in epithelial cells lining the efferent ducts and epididymis during postnatal development
10. Analysis of differentially expressed genes in retinitis pigmentosa retinas. Altered expression of clusterin mRNA
11. Expression of clusterin in cell differentiation and cell death
12. Glial responses, clusterin, and complement in permanent focal cerebral ischemia in the mouse
13. Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death
14. Expression of clusterin (testosterone-repressed prostate message-2) mRNA during growth and regeneration of rat liver
15. Clusterin protects granulosa cells from apoptotic cell death during follicular atresia
16. Antisense oligonucleotide of clusterin mRNA induces apoptotic cell death and prevents adhesion of rat ASC-17D Sertoli cells
17. Testosterone-repressed prostate message-2 is an antiapoptotic gene involved in progression to androgen independence in prostate cancer
18. Estrogenic regulation of clusterin mRNA in normal and malignant endometrial tissue
19. Localization of sulfated glycoprotein-2 (cluster-in) on spermatozoa and in the reproductive tract of the male rat
20. Tumour progression is accompanied by significant changes in the levels of expression of polyamine metabolism regulatory genes and clusterin (sulfated glycoprotein 2) in human prostate cancer specimens
21. Increased levels of clusterin mRNA in the ventral prostate of the aging rat are associated to increases in cuboidal (atrophic) cell population and not to changes in apoptotic activity
22. Overexpression of clusterin in human breast carcinoma
23. Purification and characterization of a cell-aggregating factor (clusterin), the major glycoprotein in ram rete testis fluid
24. Immunohistological localization of clusterin in the male genital tract in humans and marmosets
25. Developmental expression of sulfated glycoprotein-2 in the epididymis of the rat
26. Clusterin in the male reproductive system: Localization and possible function
27. Activity and form of sulfated glycoprotein 2 (clusterin) from cultured Sertoli cells, testis, and epididymis of the rat
28. Acquisition of chemoresistant phenotype by overexpression of the antiapoptotic gene testosterone-repressed prostate message-2 in prostate cancer xenograft models
29. Detection of differentially expressed genes in lymphomas using cDNA arrays: Identification of clusterin as a new diagnostic marker for anaplastic large-cell lymphomas
30. Apoptosis in human ejaculated sperm cells (notulae seminologicae 9)
31. Measuring apoptosis in human spermatozoa: A biological assay for semen quality?
32. Germ cell suicide: New insights into apoptosis during spermatogenesis
33. Extent of apoptosis in relation to p53 and bcl-2 expression in germ cell tumours